Patents by Inventor John D. Burr
John D. Burr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190060588Abstract: An aerosolization apparatus comprises a body having an inlet, an endpiece having an outlet, the endpiece being connectable to the body to define a chamber, wherein the chamber is sized to receive a capsule containing a pharmaceutical formulation in a manner which allows the capsule to move within the chamber. The apparatus further includes a connection mechanism to provide selective connection of the endpiece to the body, wherein a rotational force between the endpiece and the body is needed to connect or disconnect the endpiece from the body, the rotational force being applied about an axis passing through the chamber. When a user inhales, air enters into the chamber through the inlet so that the pharmaceutical formulation is aerosolized within the chamber and the aerosolized pharmaceutical formulation is delivered to the user through the outlet. The connection mechanism prevents inadvertent disconnection of the endpiece from the body.Type: ApplicationFiled: October 25, 2018Publication date: February 28, 2019Applicant: BGP PRODUCTS OPERATIONS GmbHInventors: John D. Burr, Jeff R. Wood, Adrian E. Smith, John A. Howard, Niccolai Fabrizio
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Patent number: 10124128Abstract: An aerosolization apparatus comprises a body having an inlet, an endpiece having an outlet, the endpiece being connectable to the body to define a chamber, wherein the chamber is sized to receive a capsule containing a pharmaceutical formulation in a manner which allows the capsule to move within the chamber. The apparatus further includes a connection mechanism to provide selective connection of the endpiece to the body, wherein a rotational force between the endpiece and the body is needed to connect or disconnect the endpiece from the body, the rotational force being applied about an axis passing through the chamber. When a user inhales, air enters into the chamber through the inlet so that the pharmaceutical formulation is aerosolized within the chamber and the aerosolized pharmaceutical formulation is delivered to the user through the outlet. The connection mechanism prevents inadvertent disconnection of the endpiece from the body.Type: GrantFiled: November 14, 2002Date of Patent: November 13, 2018Assignee: BGP Products Operations GmbHInventors: John D. Burr, Jeff R. Wood, Adrian E. Smith, John A. Howard, Fabrizio Niccolai
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Patent number: 8161969Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: GrantFiled: March 21, 2008Date of Patent: April 24, 2012Assignee: Novartis AGInventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herm Snyder, Carlos A. Schuler, George S. Axford, Charles Ray
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Patent number: 7516741Abstract: An aerosolization apparatus comprises a housing defining a chamber having an air inlet and an air outlet, wherein the chamber is sized to receive a capsule containing a pharmaceutical formulation. A puncturing member is moveable within the chamber to contact the capsule and to provide an opening in the capsule, and a feedback mechanism provides an indication, such as a tactile indication, to a user when the puncturing member has been moved to a position where it provides the opening into the capsule. When air flows through the inlet, the pharmaceutical formulation is aerosolized and the aerosolized pharmaceutical formulation is delivered through the outlet.Type: GrantFiled: November 7, 2003Date of Patent: April 14, 2009Inventors: Mark J. Glusker, Jeff R. Wood, John D. Burr
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Publication number: 20080230058Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: ApplicationFiled: March 21, 2008Publication date: September 25, 2008Applicant: Nektar TherapeuticsInventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herm Snyder, Carlos A. Schuler, George S. Axford, Charles Ray
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Patent number: 7422013Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: GrantFiled: March 9, 2005Date of Patent: September 9, 2008Assignee: Nektar TherapeuticsInventors: John D. Burr, Adrian E. Smith, George S. Axford
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Patent number: 6901929Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: GrantFiled: December 19, 2002Date of Patent: June 7, 2005Assignee: Nektar TherapeuticsInventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herman Snyder, Carlos Schuler, George S. Axford, Charles Ray
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Publication number: 20040206350Abstract: An aerosolization apparatus comprises a body defining a chamber having an air inlet and an air outlet. The chamber is sized to receive a receptacle containing a pharmaceutical formulation in a manner which allows the receptacle to move within the chamber. The chamber comprises a longitudinal axis, and the chamber has a cross-section orthogonal to its longitudinal axis that is non-circular. When a user inhales, air enters into the chamber through the inlet to cause the receptacle to move within the chamber so that the pharmaceutical formulation exits through an opening in the receptacle and is aerosolized for delivery to the user through the outlet.Type: ApplicationFiled: November 14, 2003Publication date: October 21, 2004Applicant: Nektar TherapeuticsInventors: William W. Alston, Jeff Wood, John D. Burr, Mark Glusker
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Publication number: 20030209243Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: ApplicationFiled: December 19, 2002Publication date: November 13, 2003Applicant: Inhale Therapeutic SystemsInventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herman Snyder, Carlos Schuler, George S. Axford, Charles Ray
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Publication number: 20030183229Abstract: A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.Type: ApplicationFiled: February 6, 2003Publication date: October 2, 2003Applicant: INHALE THERAPEUTIC SYSTEMS, a corporation of the State of CaliforniaInventors: Adrian E. Smith, John D. Burr, Jeffrey W. Etter, George S. Axford, Jack M. Anthony
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Publication number: 20030150454Abstract: An aerosolization apparatus comprises a body having an inlet, an endpiece having an outlet, the endpiece being connectable to the body to define a chamber, wherein the chamber is sized to receive a capsule containing a pharmaceutical formulation in a manner which allows the capsule to move within the chamber. The apparatus further includes a connection mechanism to provide selective connection of the endpiece to the body, wherein a rotational force between the endpiece and the body is needed to connect or disconnect the endpiece from the body, the rotational force being applied about an axis passing through the chamber. When a user inhales, air enters into the chamber through the inlet so that the pharmaceutical formulation is aerosolized within the chamber and the aerosolized pharmaceutical formulation is delivered to the user through the outlet. The connection mechanism prevents inadvertent disconnection of the endpiece from the body.Type: ApplicationFiled: November 14, 2002Publication date: August 14, 2003Applicant: Inhale Therapeutic Systems, Inc.Inventors: John D. Burr, Jeff R. Wood, Adrian E. Smith, John A. Howard, Fabrizio Niccolai
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Publication number: 20030094173Abstract: An aerosolization apparatus comprises a body having an inlet, an endpiece having an outlet, the endpiece being connectable to the body to define a chamber, wherein the chamber is sized to receive a capsule containing a pharmaceutical formulation in a manner which allows the capsule to move within the chamber. A connection mechanism is provided to provide selective connection of the endpiece to the body, and a locking member prevents undesired disconnection of the endpiece from the body. When a user inhales, air enters into the chamber through the inlet so that the pharmaceutical formulation is aerosolized within the chamber and the aerosolized pharmaceutical formulation is delivered to the user through the outlet. In another version, the endpiece and the body are hinged together.Type: ApplicationFiled: November 14, 2002Publication date: May 22, 2003Applicant: Inhale Therapeutic Systems, Inc.Inventors: John D. Burr, Jeff R. Wood, Adrian E. Smith, John A. Howard
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Patent number: 6546929Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: GrantFiled: June 4, 2001Date of Patent: April 15, 2003Assignee: Inhale Therapeutic Systems, Inc.Inventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herman Snyder, Carlos Schuler, George S. Axford, Charles Ray
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Patent number: 6543448Abstract: A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.Type: GrantFiled: May 30, 2000Date of Patent: April 8, 2003Assignee: Inhale Therapeutic Systems, Inc.Inventors: Adrian E. Smith, John D. Burr, Jeffrey W. Etter, George S. Axford, Jack M. Anthony
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Publication number: 20020017297Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: ApplicationFiled: June 4, 2001Publication date: February 14, 2002Inventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herman Snyder, Carlos Schuler, George S. Axford, Charles Ray
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Patent number: 6257233Abstract: The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position.Type: GrantFiled: May 14, 1999Date of Patent: July 10, 2001Assignee: Inhale Therapeutic SystemsInventors: John D. Burr, Adrian E. Smith, Randy K. Hall, Herman Snyder, Carlos Schuler, George S. Axford, Charles Ray
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Patent number: 6089228Abstract: A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.Type: GrantFiled: January 8, 1998Date of Patent: July 18, 2000Assignee: Inhale Therapeutic SystemsInventors: Adrian E. Smith, John D. Burr, Jeffrey W. Etter, George S. Axford, Jack M. Anthony
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Patent number: 5785049Abstract: A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.Type: GrantFiled: September 21, 1994Date of Patent: July 28, 1998Assignee: Inhale Therapeutic SystemsInventors: Adrian E. Smith, John D. Burr, Jeffery W. Etter, George S. Axford, Shirley W. Lyons, Robert M. Platz
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Patent number: 5740794Abstract: A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.Type: GrantFiled: June 7, 1995Date of Patent: April 21, 1998Assignee: Inhale Therapeutic SystemsInventors: Adrian E. Smith, John D. Burr, Jeffrey W. Etter, George S. Axford, Jack M. Anthony
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Patent number: D390651Type: GrantFiled: December 12, 1996Date of Patent: February 10, 1998Assignee: Inhale Therapeutics SystemsInventors: Adrian E. Smith, John D. Burr, Jeffrey W. Etter, George S. Axford