Patents by Inventor John D. Crispino

John D. Crispino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimethyl fasudil for inducing polyploidization of megakaryocytes and for treating blood and bone marrow diseases and disorders
    Patent number: 8933071
    Abstract: Disclosed are methods for inducing polyploidization of megakaryocyte cells and for promoting differentiation of megakaryocyte cells into platelet-producing cells. The methods may be utilized for treating blood and bone marrow diseases and disorders in a subject in need thereof and for identifying agents for treating blood and bone marrow diseases and disorders.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: January 13, 2015
    Assignees: Northwestern University, Massachusetts Institute of Technology
    Inventors: John D. Crispino, Qiang Wen, Zan Huang, Andrew M. Stern, Robert J. Gould
  • METHODS FOR INDUCING POLYPLOIDIZATION OF MEGAKARYOCYTES AND FOR TREATING BLOOD AND BONE MARROW DISEASES AND DISORDERS
    Publication number: 20100120750
    Abstract: Disclosed are methods for inducing polyploidization of megakaryocyte cells and for promoting differentiation of megakaryocyte cells into platelet-producing cells. The methods may be utilized for treating blood and bone marrow diseases and disorders in a subject in need thereof and for identifying agents for treating blood and bone marrow diseases and disorders.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 13, 2010
    Applicant: Northwestern University
    Inventors: John D. Crispino, Qiang Wen, Zan Huang, Andrew M. Stern, Robert J. Gould