Patents by Inventor John D. DiMarco

John D. DiMarco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphs of an epothilone analog
    Patent number: 7153879
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: December 26, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Polymorphs of an epothilone analog
    Patent number: 6982276
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: January 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Paclitaxel solvates
    Patent number: 6858644
    Abstract: Biologically active crystalline solvates of paclitaxel are precipitated using polar, aprotic, organic solvents. A pharmaceutical composition is also disclosed, as well as the preparation of the novel solvates and their uses as anti-tumor agents.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: February 22, 2005
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Daniel A. Benigni, Jack Z. Gougoutas, John D. DiMarco
  • Polymorphs of an epothilone analog
    Publication number: 20040157897
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula 1
    Type: Application
    Filed: February 6, 2004
    Publication date: August 12, 2004
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Polymorphs of an epothilone analog
    Patent number: 6689802
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: February 10, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Paclitaxel solvates
    Publication number: 20030144344
    Abstract: Biologically active crystalline solvates of paclitaxel are precipitated using polar, aprotic, organic solvents. A pharmaceutical composition is also disclosed, as well as the preparation of the novel solvates and their uses as anti-tumor agents.
    Type: Application
    Filed: November 26, 2002
    Publication date: July 31, 2003
    Inventors: Daniel A. Benigni, Jack Z. Gougoutas, John D. DiMarco
  • Polymorphs of an epothilone analog
    Publication number: 20020188014
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula 1
    Type: Application
    Filed: August 9, 2001
    Publication date: December 12, 2002
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Gatifloxacin pentahydrate
    Patent number: 6413969
    Abstract: There are provided in accordance with the present invention crystalline gatifloxacin pentahydrate represented by the formula in a highly homogeneous form with respect to other crystalline forms thereof.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 2, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Krishnaswamy S. Raghavan, Sunanda A. Ranadive, Jack Z. Gougoutas, John D. DiMarco, William L. Parker, Martha Davidovich, Ann Newman
  • Gatifloxacin pentahydrate
    Publication number: 20020052379
    Abstract: There are provided in accordance with the present invention crystalline gatifloxacin pentahydrate represented by the formula 1
    Type: Application
    Filed: August 17, 2001
    Publication date: May 2, 2002
    Inventors: Krishnaswamy S. Raghavan, Sunanda A. Ranadive, Jack Z. Gougoutas, John D. DiMarco, William L. Parker, Martha Davidovich, Ann Newman