Patents by Inventor John D. Dye

John D. Dye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190292165
    Abstract: The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of filovirus infection in humans and other mammals. A new class of small molecules is disclosed that inhibits the interaction of naturally processed (i.e., proteolytically cleaved) filovirus glycoprotein (GPCL) with its host receptor Niemann-Pick C1 (NPC1) protein and thus block infection of host cells by filoviruses. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of filovirus infection.
    Type: Application
    Filed: December 5, 2017
    Publication date: September 26, 2019
    Applicants: Microbiotix, Inc., Albert Einstein College Of Medicine, Inc., The Govermnment Of The United States As Represented By The Secretary Of The Army
    Inventors: Terry L. Bowlin, Donald T. Moir, Kartik Chandran, John M. Dye, John D. Williams, Zachary D. Aron, Jay P. Barbor, Kelly N. Lively, Peter J. Nash, Debra M. Mills, Arnab Basu
  • Patent number: 5383894
    Abstract: A compression device for applying compressive pressures against a patient's limb through means of a flexible, pressurizable sleeve which encloses a limb. The compression device has a pressure control apparatus which includes a microprocessor, a driver circuit and a flow control valve having a stepper motor attached thereto. The microprocessor is programmed to control pressure to the sleeve in conjunction with the driver circuit and the flow control valve by actuating the stepper motor. The microprocessor compares a signal generated by a pressure transducer to a preselected pressure value, it then generates an electrical signal to a driver circuit which in turn sends pulses to the stepper motor to automatically adjust the flow control valve, thus, controlling the flow of fluid therethrough so as to maintain a preselected pressure applied to the limb by the pressure chamber of the sleeve.
    Type: Grant
    Filed: July 30, 1993
    Date of Patent: January 24, 1995
    Assignee: The Kendall Co.
    Inventor: John D. Dye