Patents by Inventor John D. Fikes

John D. Fikes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression vectors for stimulating an immune response and methods of using the same
    Publication number: 20030216342
    Abstract: The present invention relates to nucleic acid vaccines encoding multiple CTL and HTL epitopes and MHC targeting sequences.
    Type: Application
    Filed: February 21, 2003
    Publication date: November 20, 2003
    Inventors: John D. Fikes, Gary G. Hermanson, Alessandro Sette
  • Expression vectors for stimulating an immune response and methods of using the same
    Publication number: 20030203869
    Abstract: The present invention relates to nucleic acid vaccines encoding multiple CTL and HTL epitopes and MHC targeting sequences.
    Type: Application
    Filed: February 21, 2003
    Publication date: October 30, 2003
    Inventors: John D. Fikes, Gary G. Hermanson, Alessandro Sette
  • HLA class I A2 tumor associated antigen peptides and vaccine compositions
    Patent number: 6602510
    Abstract: A composition or vaccine composition comprising eight isolated epitopes consisting of YLSGANLNV (SEQ. ID. NO: 1), IMIGVLVGV (SEQ. ID. NO: 2), KLBPVQLWV (SEQ. ID. NO: 3), SMPPPGTRV (SEQ. ID. NO: 4), KVAELVHFL (SEQ. ID. NO: 5), YLQLVFGIEV (SEQ. ID. NO: 6), RLLQETELV (SEQ. ID. NO: 7), and, VVLGVVFGI (SEQ. ID. NO: 8).
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: August 5, 2003
    Assignee: Epimmune Inc.
    Inventors: John D. Fikes, Alessandro Sette, John Sidney, Scott Southwood, Esteban Celis, Elissa A. Keogh, Robert Chesnut
  • Heteroclitic analogs and related methods
    Publication number: 20030143672
    Abstract: Heteroclitic analogs of Class I epitopes are prepared by providing conservative or semi-conservative amino acid substitutions at positions 3 and/or 5 and/or 7 of these epitopes. The analogs are useful in eliciting immune responses with respect to the corresponding wildtype epitopes.
    Type: Application
    Filed: April 5, 2002
    Publication date: July 31, 2003
    Applicant: Epimmune, Inc.
    Inventors: Shabnam Tangri, Alessandro Sette, Glenn Ishioka, John D. Fikes
  • Expression vectors for stimulating an immune response and methods of using the same
    Patent number: 6534482
    Abstract: The present invention relates to nucleic acid vaccines encoding multiple CTL and HTL epitopes and MHC targeting sequences.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: March 18, 2003
    Assignee: Epimmune, Inc.
    Inventors: John D. Fikes, Gary G. Hermanson, Alessandro Sette, Glenn Y. Ishioka, Brian Livingston, Robert W. Chesnut
  • MAGE-1 c-terminal immunogenic peptides
    Patent number: 6464980
    Abstract: The complete nucleotide and amino acid sequences of the human MAGE-1 antigen are provided. Peptides from residues of the C-terminal are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against MAGE-1 antigens. The peptides are particularly useful in methods for stimulating the immune response of individuals against MAGE-1 antigens associated with melanomas.
    Type: Grant
    Filed: April 2, 1996
    Date of Patent: October 15, 2002
    Assignee: Epimmune Inc.
    Inventors: John D. Fikes, Brian D. Livingston, Alessandro D. Sette, John C. Sidney
  • DNA encoding MAGE-1 C-terminal cytotoxic t lymphocyte immunogenic peptides
    Patent number: 5750395
    Abstract: The complete nucleotide and amino acid sequences of the human MAGE-1 antigen are provided. Peptides from residues of the C-terminal are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against MAGE-1 antigens. The peptides are particularly useful in methods for stimulating the immune response of individuals against MAGE-1 antigens associated with melanomas.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 12, 1998
    Assignee: Cytel Corporation
    Inventors: John D. Fikes, Brian D. Livingston, Alessandro D. Sette, John C. Sidney