Patents by Inventor John D. Gilbert

John D. Gilbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxidization metabolites of 5-.alpha.-23-methyl-4-aza-21-nor-chol-1-ene-3, 20-dione
    Patent number: 5324734
    Abstract: The compounds of formula (I) ##STR1## wherein R is selected from the group hydroxymethyl and carboxy, have been identified as metabolites of 5.alpha.-23-methyl-4-aza-21-nor-chol-1-ene-3,20-dione and are believed to be active as testosterone 5.alpha.-reductase inhibitors and would thus be useful for treatment of acne, seborrhea, female hirsutism or benign prostatic hypertrophy.
    Type: Grant
    Filed: September 15, 1992
    Date of Patent: June 28, 1994
    Assignee: Merck & Co., Inc.
    Inventors: John D. Gilbert, Timothy V. Olah