Patents by Inventor John D. GINN

John D. GINN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS
    Publication number: 20240043470
    Abstract: The compounds of the present invention are represented by the following compounds having Formula I and Formula (I?): where the substituents R1, R2, R2?, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein and where the substituents R1, R2, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
    Type: Application
    Filed: September 25, 2023
    Publication date: February 8, 2024
    Inventors: Gang LIN, Carl NATHAN, Laura KIRKMAN, Wenhu ZHAN, Trevor MORGAN, Kenjiro SATO, Ryoma HARA, Masanori KAWASAKI, Toshihiro IMAEDA, Akinori TOITA, Rei OKAMOTO, Takafumi YUKAWA, Kazuyoshi ASO, Tzu-Tshin WONG, John D. GINN, Michael A. FOLEY
  • Macrocyclic compounds as proteasome inhibitors
    Patent number: 11834515
    Abstract: The compounds of the present invention are represented by the following compounds having Formula I and Formula (I?): where the substituents R1, R2, R2?, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein and where the substituents R1, R2, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: December 5, 2023
    Assignees: CORNELL UNIVERSITY, TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE
    Inventors: Gang Lin, Carl Nathan, Laura Kirkman, Wenhu Zhan, Trevor Morgan, Kenjiro Sato, Ryoma Hara, Masanori Kawasaki, Toshihiro Imaeda, Akinori Toita, Rei Okamoto, Takafumi Yukawa, Kazuyoshi Aso, Tzu-Tshin Wong, John D. Ginn, Michael A. Foley
  • MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS
    Publication number: 20220324907
    Abstract: The compounds of the present invention are represented by the following compounds having Formula I and Formula (I?): where the substituents R1, R2, R2?, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein and where the substituents R1, R2, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
    Type: Application
    Filed: October 11, 2018
    Publication date: October 13, 2022
    Inventors: Gang LIN, Carl NATHAN, Laura KIRKMAN, Wenhu ZHAN, Trevor MORGAN, Kenjiro SATO, Ryoma HARA, Masanori KAWASAKI, Toshihiro IMAEDA, Akinori TOITA, Rei OKAMOTO, Takafumi YUKAWA, Kazuyoshi ASO, Tzu-Tshin WONG, John D. GINN, Michael A. FOLEY