Patents by Inventor John D. Young
John D. Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190183960Abstract: The present invention provides a method to treat asthma and airway allergy by administering the dipeptide cyclo tyrosine-valine or a related cyclodipeptide compound to a subject in need thereof. Cyclo tyrosine-valine or the related cyclodipeptide compound reduces Th2 cell activation, airway hyperresponsiveness, accumulation of immune cells in bronchoalveolar fluid, and allergen-specific antibody production in an animal or human subject. The compound can therefore be used to treat asthma and airway allergy.Type: ApplicationFiled: February 27, 2018Publication date: June 20, 2019Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, Chen-Yaw Chiu, Chuan-Sheng Lin, Luis Dominick B. Antig, Pei-Wen Hsieh, Yu-Li Chen, Chih-Jung Chang, Tsung-Ru Wu, David Marcelo Ojcius, Chia-Chen Lu, Hsin-Chih Lai, John D. Young
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Patent number: 10111915Abstract: The present invention describes a method to reduce blood aspartate transaminase level, liver weight, hepatic lipid accumulation and hepatocyte hypertrophy by administering the probiotic bacterium Parabacteroides goldsteinii to a subject showing signs of fatty liver disease. This probiotic bacterium can therefore be used to treat fatty liver disease.Type: GrantFiled: November 16, 2017Date of Patent: October 30, 2018Assignee: CHANG GUNG BIOTECHNOLOGY CORP.Inventors: Yun-Fei Ko, Jan Martel, Tsung-Ru Wu, Chih-Jung Chang, Chuan-Sheng Lin, Jian-Ching Liau, Wei-Chang Wang, Chen-Yaw Chiu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
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Patent number: 10086019Abstract: The present invention provides a method to reduce insulin resistance and improve glucose tolerance by administering the probiotic bacterium Parabacteroides goldsteinii. This probiotic bacterium can therefore be used to treat insulin resistance, metabolic syndrome, and type 2 diabetes.Type: GrantFiled: October 23, 2017Date of Patent: October 2, 2018Assignee: CHANG GUNG BIOTECHNOLOGY CORP.Inventors: Yun-Fei Ko, Jan Martel, Tsung-Ru Wu, Chih-Jung Chang, Chuan-Sheng Lin, Jian-Ching Liau, Wei-Chang Wang, Chen-Yaw Chiu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
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Patent number: 9956255Abstract: The present invention describes a method to reduce body weight, fat accumulation and adipocyte size by administering the probiotic bacterium Parabacteroides goldsteinii. This probiotic bacterium can therefore be used to treat obesity in animals and humans.Type: GrantFiled: October 9, 2017Date of Patent: May 1, 2018Assignee: CHANG GUNG BIOTECHNOLOGY CORP.Inventors: Yun-Fei Ko, Jan Martel, Tsung-Ru Wu, Chih-Jung Chang, Chuan-Sheng Lin, Jian-Ching Liau, Wei-Chang Wang, Chen-Yaw Chiu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
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Patent number: 9763990Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce liver weight and liver lipid content in humans and animals. The prepared polysaccharides can therefore be used to prevent and treat fatty liver disease.Type: GrantFiled: September 23, 2015Date of Patent: September 19, 2017Assignee: Chang Gung Biotechnology Corp.Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
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Patent number: 9758595Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides reduce body weight and fat accumulation in laboratory animals, and can therefore be used to prevent and treat obesity.Type: GrantFiled: September 15, 2015Date of Patent: September 12, 2017Assignee: Chang Gung Biotechnology Corp.Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
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Patent number: 9757409Abstract: The present invention provides a method to prepare polysaccharides from Ganoderma lucidum. The prepared polysaccharides can reduce hyperglycemia and improve insulin sensitivity in humans and animals, and can therefore be used to prevent and treat type 2 diabetes.Type: GrantFiled: September 15, 2015Date of Patent: September 12, 2017Assignee: Chang Gung Biotechnology Corp.Inventors: Yun-Fei Ko, Jan Martel, Jian-Ching Liau, I-Te Chang, Wei-Ting Jian, Mei-Feng Lin, Chia-Jen Yang, Chen-Yaw Chiu, Chih-Jung Chang, Chuan-Sheng Lin, Tsung-Ru Wu, Chia-Chen Lu, David Marcelo Ojcius, Hsin-Chih Lai, John D. Young
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Publication number: 20160130123Abstract: A preferred embodiment of the invention is directed to a jack apparatus that is electrically operated with a rechargeable battery. The jack apparatus has a base section and a telescopic jack and wrench. The wrench is most preferably a power lug wrench for removing the lug nuts from an automobile, but any socket, bit, or connection available for power drills is compatible. One embodiment comprises the apparatus having a 12 v outlet cord in addition to the battery. A preferred embodiment comprises the jack apparatus having a power inverter housed therein.Type: ApplicationFiled: November 7, 2014Publication date: May 12, 2016Inventor: John D. Young
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Publication number: 20150209470Abstract: An oxygenated oil ointment is made, for example, by stirring or agitating plant-based oil while injecting a gas into the plant-based oil, resulting in a coagulated ointment that is beneficial for topical application. In one example, the plant-based oil is olive oil and the gas includes ozone, which is known to kill pathogens. For some plant-based oils, the ozone increases amounts of peroxide in the plant-based oils. Once the olive oil coagulates with the ozone, the resulting ointment retains some of the ozone gas until the ointment is applied on the skin for treatment of, for example, cuts and sores. In some ointments, the pH of the plant-based oil is increased by adding one or more alkaline materials to the plant-based oil before coagulation occurs. This increase in alkalinity improves the ointment's ability to give off ozone and oxygen.Type: ApplicationFiled: January 28, 2015Publication date: July 30, 2015Inventor: John D. Young
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Patent number: 8365331Abstract: The auto powered jack apparatus provides for selective telescopic extension of the jack shaft. The telescopic jack is especially useful for lifting an auto. The jack is in removable communication with either the air compressor or the electrical inverter, both powered by a cigar lighter plug removably fitted into a cigar lighter. The apparatus also provides for wrenching any given object with the powered handgun shaped wrench. The jack is omni directionally operated so that objects may be separated as chosen and other functions performed with the jack. The inverter converts 12 volt auto power to 120 volt electrical power so that the wrench and jack are able to operate with sufficient power to lift a car and to remove and replace highly torqued auto items such as wheel lug nuts, as compared to 12 volt wrench and jack operations that are typically woefully inadequate when faced with laborious tasks.Type: GrantFiled: November 5, 2010Date of Patent: February 5, 2013Inventor: John D. Young
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Patent number: 7108848Abstract: A gel formulation is combined with a fungicidal concentrate which is a liquid mixture of about 1.2 to 16 ml parts by volume of ultra pure water having an electrical resistance of 16–26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 mho with about 1.2 to 16 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943, together with one liter of a gel formulation ingredient containing 10% by weight urea, based on the weight of the gel formulation. The fungicidal liquid concentrate is applied directly to a fungal nail to soften the fungal nail and control the growth of fungi.Type: GrantFiled: July 20, 2004Date of Patent: September 19, 2006Assignee: Aqua Med, Inc.Inventors: John D. Young, Alberto Hoyo
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Patent number: 6692775Abstract: A gel formulation is combined with a bactericidal concentrate which is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 mho with about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The bactericidal liquid concentrate in the amount of 3.5 to 12 ml in one liter of gel formulation is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.Type: GrantFiled: June 24, 2002Date of Patent: February 17, 2004Assignee: Aqua Med, Inc.Inventor: John D. Young
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Publication number: 20020168387Abstract: A gel formulation is combined with a bactericidal concentrate which is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 mho with about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The bactericidal liquid concentrate in the amount of 3.5 to 12 ml in one liter of gel formulation is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.Type: ApplicationFiled: June 24, 2002Publication date: November 14, 2002Applicant: AQUA MED, INC.Inventor: John D. Young
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Patent number: 6416790Abstract: The concentrate is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 microhmo to about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The liquid concentrate is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.Type: GrantFiled: March 13, 2000Date of Patent: July 9, 2002Assignee: Aqua Med, Inc.Inventor: John D. Young
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Patent number: 6391267Abstract: A method and system for reducing pollutant concentration within an internal combustion engine exhaust stream is disclosed. Soot and products of incomplete combustion in the engine exhaust stream are destroyed by oxidizing them in a flameless thermal oxidizer that contains a matrix of heat-resistant media. Methods and systems for increasing particle residence time within the thermal oxidizer are also disclosed. These techniques include employing electrostatic precipitation, centrifugal force, and particle impaction sections. A method and system for reducing oxides of nitrogen (NOx) emissions is also disclosed. Low NOx concentration may be obtained by adding a SCR system after a thermal oxidizer, by tuning the engine to produce low NOx/high soot and destroying the soot in a thermal oxidizer, and by injecting a reductant into the thermal oxidizer. The flameless thermal oxidizer may be located between the engine and a turbo-charger to enhance thermal efficiency and to reduce turbo-charger wear.Type: GrantFiled: September 17, 1999Date of Patent: May 21, 2002Assignee: Thermatrix, Inc.Inventors: Richard J. Martin, John D. Stilger, Mark R. Holst, John D. Young, Michael P. Barkdoll, Bradley L. Edgar
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Patent number: 6257869Abstract: A matrix bed is disclosed in which a non-planar reaction wave front is formed during operation. This is accomplished by heating the matrix bed, containing heat-resistant material, until at least a reaction portion of the matrix bed is above the temperature required for a plurality of reactant gas streams to react. Next, the reactant gas streams are directed through the matrix bed in a manner so as to form at least a Bunsen, Burke-Schumann, inverted-V, or some other type of non-planar reaction wave front at the portion of the matrix bed that is heated above the reactant gas streams reaction temperature. At the non-planar reaction wave front, the reactant gas streams react to produce a reaction product gas stream that is then exhausted from the matrix bed.Type: GrantFiled: October 13, 1999Date of Patent: July 10, 2001Assignee: Thermatrix, Inc.Inventors: Richard J. Martin, John D. Stilger, Mark R. Holst, John D. Young, Bradley L. Edgar
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Patent number: 6003305Abstract: A process is provided for preparing oxymorphone from morphine by:(1) reacting morphine with (1a) an acyl halide or anhydride to form 3-acylmorphine, or (1b) reacting morphine with benzyl-halide to form 3-benzylmorphine;(2) Oxidizing the 6-hydroxy group of the 3-acyl or 3-benzylmorphine so as to form the corresponding 3-acyl or 3-benzylmorphinone; and thereafter either by (3a) or (3b):(3a) introducing a .beta.-oriented hydroxy group at the 14-position of the 3-acyl- or 3-benzyl-morphinone with aqueous hydrogen peroxide and an acid at a temperature of about 15.degree. to about 70.degree. C.Type: GrantFiled: September 2, 1997Date of Patent: December 21, 1999Assignee: Thermatrix, Inc.Inventors: Richard J. Martin, John D. Stilger, Mark R. Holst, John D. Young, Michael P. Barkdoll, Bradley L. Edgar
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Patent number: 5989010Abstract: A matrix bed is disclosed in which a non-planar reaction wave front is formed during operation. This is accomplished by heating the matrix bed, containing heat-resistant material, until at least a reaction portion of the matrix bed is above the temperature required for a plurality of reactant gas streams to react. Next, the reactant gas streams are directed through the matrix bed in a manner so as to form at least a Bunsen, Burke-Schumann, inverted-V, or some other type of non-planar reaction wave front at the portion of the matrix bed that is heated above the reactant gas streams reaction temperature. At the non-planar reaction wave front, the reactant gas streams react to produce a reaction product gas stream that is then exhausted from the matrix bed.Type: GrantFiled: September 2, 1997Date of Patent: November 23, 1999Assignee: Thermatrix, Inc.Inventors: Richard J. Martin, John D. Stilger, Mark R. Holst, John D. Young, Bradley L. Edgar
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Patent number: 5830452Abstract: The present application relates to a method for enhancing the therapeutic index of a compound that is useful to treat tumors. More specifically, the present invention relates to a method for administering IL-2 to a tumor patient to maximize the therapeutic efficacy and minimize the toxicity.Type: GrantFiled: July 11, 1994Date of Patent: November 3, 1998Assignee: Chiron CorporationInventors: Robert J. Bauer, Jeffrey L. Winkelhake, John D. Young, Robert Zimmerman
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Patent number: 5817286Abstract: Processes for the production of hydrogen cyanide from the reaction of methane with ammonia at temperatures above about 800.degree. C. where the reactor contains a matrix bed of heat resistant materials. The product stream produced within the reactor is preferably routed in a countercurrent fashion to the feed stream entering the reactor to preheat the feed stream and to lower the exit temperature of the product stream. Reactors capable of being used to practice such processes are also provided by the invention.Type: GrantFiled: July 25, 1997Date of Patent: October 6, 1998Assignee: Thermatrix Inc.Inventors: Richard J. Martin, John D. Stilger, John D. Young