Patents by Inventor John Darbyshire

John Darbyshire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8263146
    Abstract: The present invention relates to any kinds of consumable products enriched with probiotics and a method for obtaining them. After production of probiotic biomass, the probiotics are applied to the product. Also metabolites obtained from a fermentation product may be directly applied to a consumable product.
    Type: Grant
    Filed: February 12, 2002
    Date of Patent: September 11, 2012
    Assignee: Nestec S.A.
    Inventors: Annmarie Bengtsson-Riveros, Johannes De Reu, Robert Dustan Wood, John Darbyshire, Hermann Knauf, Christoph Cavadini
  • Publication number: 20120095015
    Abstract: The invention relates to compounds of formula (I), wherein n is 1 or 2, Ar is a C-bound 1,2,4-triazol radical which carries a radical R1 on the remaining carbon atom and a radical R1a on one of the nitrogen atoms; R1 is hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl, C1-C4 alkoxymethyl, fluorinated C1-C6 alkyl, fluorinated C3-C6 cycloalkyl, fluorinated C1-C4 alkoxymethyl, or optionally substituted phenyl or 5- or 6-membered heteroaryl; R1a is hydrogen or C1-C4 alkyl; and R2 is C1-C6 alkyl, C3-C6 cycloalkyl, fluorinated C1-C6 alkyl or fluorinated C3-C6 cycloalkyl; and to the physiologically tolerated acid addition salts of there compounds.
    Type: Application
    Filed: December 21, 2011
    Publication date: April 19, 2012
    Inventors: Liliane Unger, Andreas Haupt, Armin Beyerbach, Karla Drescher, Wilfried Braje, John Darbyshire, Sean C. Turner, Gisela Backfisch
  • Patent number: 8101754
    Abstract: The invention relates to compounds of the formula I: wherein n is 1 or 2, Ar is a C-bound 1,2,4-triazol radical which carries a radical R1 on the remaining carbon atom and a radical R1a on one of the nitrogen atoms; R1 is hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl, C1-C4 alkoxymethyl, fluorinated C1-C6 alkyl, fluorinated C3-C6 cycloalkyl, fluorinated C1-C4 alkoxymethyl, or optionially substituted phenyl or 5- or 6-membered heteroaryl; R1a is hydrogen or C1-C4 alkyl; and R2 is C1-C6 alkyl, C3-C6 cycloalkyl, fluorinated C1-C6 alkyl or fluorinated C3-C6 cycloalkyl; and to the physiologically tolerated acid addition salts of these compounds.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: January 24, 2012
    Assignee: Abbott GmbH & Co. KG
    Inventors: Liliane Unger, Andreas Haupt, Armin Beyerbach, Karla Drescher, Wilfried Braje, John Darbyshire, Sean C. Turner, Gisela Backfisch
  • Publication number: 20100249203
    Abstract: Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: June 14, 2010
    Publication date: September 30, 2010
    Applicant: Abbott Laboratories
    Inventors: Chih-hung Lee, Richard J. Perner, Brian S. Brown, John Darbyshire
  • Patent number: 7767705
    Abstract: Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: August 3, 2010
    Assignee: Abbott Laboratories
    Inventors: Chih-hung Lee, Richard J Perner, Brian S. Brown, John Darbyshire
  • Publication number: 20080171751
    Abstract: The invention relates to compounds of the formula I: wherein n is 1 or 2, Ar is a C-bound 1,2,4-triazol radical which carries a radical R1 on the remaining carbon atom and a radical R1a on one of the nitrogen atoms; R1 is hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl, C1-C4 alkoxymethyl, fluorinated C1-C6 alkyl, fluorinated C3-C6 cycloalkyl, fluorinated C1-C4 alkoxymethyl, or optionally substituted phenyl or 5- or 6-membered heteroaryl; R1a is hydrogen or C1-C4 alkyl; and R2 is C1-C6 alkyl, C3-C6 cycloalkyl, fluorinated C1-C6 alkyl or fluorinated C3-C6 cycloalkyl; and to the physiologically tolerated acid addition salts of these compounds.
    Type: Application
    Filed: December 1, 2005
    Publication date: July 17, 2008
    Inventors: Liliane Unger, Andreas Haupt, Armin Beyerbach, Karla Drescher, Wilfried Braje, John Darbyshire, Sean C. Turner, Gisela Backfisch
  • Publication number: 20080058401
    Abstract: Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: August 24, 2007
    Publication date: March 6, 2008
    Applicant: Abbott Laboratories
    Inventors: Chih-hung Lee, Richard Perner, Brian Brown, John Darbyshire
  • Patent number: 6953592
    Abstract: The invention relates to water soluble or water dispersible powders, tablets, or precursors therefor based on a carbohydrate matrix with improved dissolution properties in water. These components are subjected to treatment with a gas so that gas is entrapped therein, and sufficient closed porosity is provided so that gas entrapped therein promotes dissolution or dispersion upon contact with water. The powders or tablets may be pharmaceuticals or foods that optionally contain an active ingredient therein.
    Type: Grant
    Filed: September 4, 2002
    Date of Patent: October 11, 2005
    Assignee: Nestec S.A.
    Inventors: John Darbyshire, Oliver Chmiel, Johan Bernard Ubbink, Annemarie Schoonman
  • Publication number: 20040115308
    Abstract: The present invention relates to any kinds of consumable products enriched with probiotics and a method for obtaining them. After production of probiotic biomass, the probiotics are applied to the product. Also metabolites obtained from a fermentation product may be directly applied to a consumable product.
    Type: Application
    Filed: February 2, 2004
    Publication date: June 17, 2004
    Inventors: Annmarie Bengtsson-Riveros, Johannes De Reu, Robert Dustan Wood, John Darbyshire, Hermann Knauf, Christoph Cavadini
  • Publication number: 20030026836
    Abstract: The invention relates to water soluble or water dispersible powders, tablets, or precursors therefor based on a carbohydrate matrix with improved dissolution properties in water. These components are subjected to treatment with a gas so that gas is entrapped therein, and sufficient closed porosity is provided so that gas entrapped therein promotes dissolution or dispersion upon contact with water. The powders or tablets may be pharmaceuticals or foods that optionally contain an active ingredient therein.
    Type: Application
    Filed: September 4, 2002
    Publication date: February 6, 2003
    Inventors: John Darbyshire, Oliver Chmiel, Johan Bernard Ubbink, Annemarie Schoonman
  • Patent number: 4815958
    Abstract: Apparatus particularly for agglomerating particles of different products. A rotatable drum, which has a wall which defines a cylinder and a cylinder void, is mounted on a frame in a horizontal or inclined position. The apparatus includes provision for rotating the cylinder in one direction thereby defining ascending and descending halves of the cylinder. A first part of the cylinder receives particles of a product and has means, such as projecting elements, to rotate the particles for forming a vortex of particles about an axis within the ascending half of the cylinder void such that the axis of the vortex is displaced from and substantially parallel to a central longitudinal axis of the cylinder.
    Type: Grant
    Filed: July 27, 1988
    Date of Patent: March 28, 1989
    Assignee: Nestec S.A.
    Inventors: Marcel Buhler, John Darbyshire, Michel Jaccard
  • Patent number: 4777056
    Abstract: In an inclined rotary drum, a vortex of a particulate main product is formed about an inclined axis, an agglomerating agent is sprayed onto the vortex from outside and a particulate secondary product is distributed in the vortex from inside.
    Type: Grant
    Filed: September 29, 1986
    Date of Patent: October 11, 1988
    Assignee: Nestec S.A.
    Inventors: Marcel Buhler, John Darbyshire, Michel Jaccard
  • Patent number: 4579739
    Abstract: A must is fermented with a combination of at least one yeast and at least one lactobacillus, the former being selected from the group of Saccharomyces cerevisiae and Kluyveromyces lactis and the latter being selected from the group of Lactobacillus casei and Lactobacillus hilgardii for their symbiotic ability and capability to produce a synergistic organoleptic effect which eliminates all after-taste of yeast. The must is inoculated such that the respective numbers of yeast germs and lactobacilli germs per ml have a ratio of from 1:10 to 1:500.
    Type: Grant
    Filed: December 13, 1983
    Date of Patent: April 1, 1986
    Assignee: Nestec S. A.
    Inventors: John Darbyshire, Jaroslav Dasek, Hugh Hose