Abstract: A system and method for providing chronic obstructive pulmonary disease (COPD) exacerbation risk notifications in real time or near-real time is described. Rescue and controller medication events are detected by sensors associated with the patient's medicament device/s, and provide a basis to determine to rescue and controller medication use trends for the patient. This data is analyzed to determine the patient's risk for COPD exacerbation after each event, and is used to send notifications to one or both of the patient and their health care provider.

Abstract: Methods and systems for delivering well stimulation materials to a wellbore using a high-pressure delivery manifold are provided. In some embodiments, the methods of the present disclosure include: providing a pressurizable delivery manifold at a well site, wherein the pressurizable delivery manifold is continuously equalized with a piping system; providing a pressurized treatment fluid to the pressurizable delivery manifold; releasing one or more well stimulation materials into the pressurized treatment fluid to create a payload delivery treatment fluid; and injecting the payload delivery treatment fluid into at least a portion of a subterranean formation.

Abstract: This invention relates to multi-purpose probe-based apparatus, and to methods for providing images of surface topography, and detection and quantitative mapping of local mechanical and electromagnetic properties in non-resonant oscillatory mode. These methods may include filtering of incoming probe signals. These incoming probe signals provide time deflection curves, parts of which are used for the control of scanning and collection of data that reflects sample adhesion, stiffness, elastic modulus and viscoelastic response, electric and magnetic interactions. These methods permit adaptive choice of an AFM's deflection set-point, which allows imaging at the contact repulsive force for precise surface profilometry, as non-resonant oscillation brings tip and sample into intermittent contact. These methods permit choosing a desired deformation model that allows an extraction of quantitative mechanical properties including viscoelastic response from deflection curves.