Abstract: There is disclosed a compound Formula I In Formula I: Z is CR4R5, C?CR4R5, SiR4R5, GeR4R5, NR4a, PR4a, P(O)R4a, O, S, SO, SO2, Se; SeO, SeO2, Te, TeO, or TeO2; R1 - R3 are the same or different at each occurrence and are D, aryl, heteroaryl, alkyl, amino, silyl, germyl, deuterated aryl, deuterated heteroaryl, deuterated alkyl, deuterated amino, deuterated silyl, or deuterated germyl, where two groups selected from R1, R2, and R3 can be joined together to form a fused ring; R4 - R5 are the same or different at each occurrence and are H, D, aryl, heteroaryl, alkyl, amino, silyl, germyl, deuterated aryl, deuterated heteroaryl, deuterated alkyl, deuterated amino, deuterated silyl, or deuterated germyl; R4a is alkyl, silyl, germyl, aryl, or a deuterated analog thereof; a is an integer from 0-4; b and c are the same or different and are an integer from 0-3.

Abstract: There is disclosed a compound Formula I In Formula I: Z is CR4R5, C?CR4R5, SiR4R5, GeR4R5, NR4a, PR4a, P(O)R4a, O, S, SO, SO2, Se; SeO, SeO2, Te, TeO, or TeO2; R1-R3 are the same or different at each occurrence and are D, aryl, heteroaryl, alkyl, amino, silyl, germyl, deuterated aryl, deuterated heteroaryl, deuterated alkyl, deuterated amino, deuterated silyl, or deuterated germyl, where two groups selected from R1, R2, and R3 can be joined together to form a fused ring; R4-R5 are the same or different at each occurrence and are H, D, aryl, heteroaryl, alkyl, amino, silyl, germyl, deuterated aryl, deuterated heteroaryl, deuterated alkyl, deuterated amino, deuterated silyl, or deuterated germyl; R4ais alkyl, silyl, germyl, aryl, or a deuterated analog thereof; a is an integer from 0-4; b and c are the same or different and are an integer from 0-3.

Abstract: There is provided a compound having Formula I In Formula I: Ar1 and Ar2 are the same or different and are aryl, heteroaryl, or deuterated analogs thereof; L1 and L2 are the same or different and are H, D, halogen, aryl, arylamino, crosslinkable groups, deuterated aryl, deuterated arylamino, or deuterated crosslinkable groups; R1-R4 are the same or different at each occurrence and are D, F, CN, hydrocarbon aryl, heteroaryl, aryloxy, fluoroaryl, alkyl, fluoroalkyl, alkoxy, fluoroalkoxy, amino, silyl, siloxane, siloxy, germyl, deuterated hydrocarbon aryl, deuterated heteroaryl, deuterated aryloxy, deuterated fluoroaryl, deuterated alkyl, deuterated fluoroalkyl, deuterated alkoxy, deuterated fluoroalkoxy, deuterated amino, deuterated silyl, deuterated siloxane, deuterated siloxy, or deuterated germyl, wherein adjacent groups selected from R1-R4 can be joined together to form a fused ring; a is 0 or 1; b is 0 or 1; x and x1 are the same or different and are an integer from 0-5; y and y1 are the same or differe

Abstract: There is provided a compound having Formula I In Formula I: Ar1 and Ar2 are the same or different and are aryl, heteroaryl, or deuterated analogs thereof; L1 and L2 are the same or different and are H, D, halogen, aryl, arylamino, crosslinkable groups, deuterated aryl, deuterated arylamino, or deuterated crosslinkable groups; R1-R4 are the same or different at each occurrence and are D, F, CN, hydrocarbon aryl, heteroaryl, aryloxy, fluoroaryl, alkyl, fluoroalkyl, alkoxy, fluoroalkoxy, amino, silyl, siloxane, siloxy, germyl, deuterated hydrocarbon aryl, deuterated heteroaryl, deuterated aryloxy, deuterated fluoroaryl, deuterated alkyl, deuterated fluoroalkyl, deuterated alkoxy, deuterated fluoroalkoxy, deuterated amino, deuterated silyl, deuterated siloxane, deuterated siloxy, or deuterated germyl, wherein adjacent groups selected from R1-R4 can be joined together to form a fused ring; a is 0 or 1; b is 0 or 1; x and x1 are the same or different and are an integer from 0-5; y and y1 are the same or differe

Abstract: There is disclosed a compound Formula I In Formula I: Z is CR4R5, C?CR4R5, SiR4R5, GeR4R5, NR4a, PR4a, P(O)R4a, O, S, SO, SO2, Se; SeO, SeO2, Te, TeO, or TeO2; R1-R3 are the same or different at each occurrence and are D, aryl, heteroaryl, alkyl, amino, silyl, germyl, deuterated aryl, deuterated heteroaryl, deuterated alkyl, deuterated amino, deuterated silyl, or deuterated germyl, where two groups selected from R1, R2, and R3 can be joined together to form a fused ring; R4-R5 are the same or different at each occurrence and are H, D, aryl, heteroaryl, alkyl, amino, silyl, germyl, deuterated aryl, deuterated heteroaryl, deuterated alkyl, deuterated amino, deuterated silyl, or deuterated germyl; R4a is alkyl, silyl, germyl, aryl, or a deuterated analog thereof; a is an integer from 0-4; b and c are the same or different and are an integer from 0-3.

Abstract: An approach is provided for scheduling work order tasks based on an optimization of available resources and an assessment of cost penalty functions for missing work order deadlines, including determining an estimated work order completion time for processing a plurality of tasks associated with a work order on one or more resources, scheduling the plurality of tasks in a processing queue based on the estimated work order completion time, and determining a value of a penalty function for violating a work order deadline.

Abstract: An approach is provided for scheduling work order tasks based on an optimization of available resources and an assessment of cost penalty functions for missing work order deadlines, including determining an estimated work order completion time for processing a plurality of tasks associated with a work order on one or more resources, scheduling the plurality of tasks in a processing queue based on the estimated work order completion time, and determining a value of a penalty function for violating a work order deadline.

Abstract: Systems and methods for core network topology router placement planning are provided. The systems and methods may use existing network data to create a data set and use the data set to optimize a network for the placement of routers.

Abstract: A microscope, endoscope or optical coherence tomograph, comprising a light source, a flexible light transmitter (18) for receiving and transmitting light from the light source, an optical element (20) with a forward end (30) for receiving the light from the light transmitter (18) and a rear wall (26) having an internal surface for reflecting the light laterally, and an external sleeve (14) enclosing the optical element (20) and transparent to the light in at least a region of the sleeve where the light is directed by the internal surface (26). The internal surface (26) has an optical figure suitable for focussing the light to an observational field (28) external to the sleeve (14). A confocal configuration may be used.

Abstract: The invention relates to a method for predicting a response to a proteasome inhibitor in the prophylaxis or treatment of a cancer in an individual. The method comprises providing a sample of cancer cells of the cancer from the individual, and evaluating the level of at least one molecule in the cancer cells associated with the unfolded protein response of the cancer cells, to provide test data indicative of the level of activity of the unfolded protein response. The test data is used to predict the response of the cancer cells to the proteasome inhibitor. The evaluation of the level of the molecule can be utilized for determination of treatment for the cancer.

Abstract: Systems and methods for core network topology router placement planning are provided. The systems and methods may use existing network data to create a data set and use the data set to optimize a network for the placement of routers.

Abstract: In a telecommunications network provisioned with a distributed restoration scheme, to determine the reactions and responses of the network while the network is “live” or operational, an exercise information message is provided to the network for presenting a simulated failure or failures thereto. This exercise information message is broadcast to all of the nodes of the network so that every node is aware of the simulated failure scenario. Modified DRA messages that indicate that they are exercise only messages are used by the nodes for executing the exercise restoration process. Such exercise restoration process will proceed as if an actual failure has occurred with the notable exception that no actual cross-connections will be made. Certain functionalities are provisioned to the nodes to allow the exercise restoration process to be aborted if a real failure is detected or upon the expiration of a timer.

Abstract: To ensure that the distributed restoration process of a DRA provisioned network proceeds only in response to true failures, the present invention DRA network provisions to each of the ports of the nodes a timer mechanism for ascertaining whether an alarm is a genuine alarm. This is done by presetting the timer with an expiration period so that an alarm is validated as a failure only upon the expiration of the timer. When validated, the value of a counter is incremented. The value of the counter is reflective of the sum of validated alarms, and is compared against a preset threshold value. And it is only when the value of the summed validated alarms exceeds the preset threshold value would the DRA process be initiated. When a validated alarm ceases, the reverse process takes place. That is, the ending of the alarm has to be validated by another timer, which could be the same timer as used for validating an alarm.

Abstract: A system and method for restoring communications in a network having multiple span failures. After a failure is detected, a sender node in each of the plurality of sender-chooser pairs sends a failed status message to the other nodes in the network. The failed status message identifies a restoration priority of the particular sender-chooser pair. Upon receipt, other nodes in the network suspend processing of lower priority restoration efforts and queue lower priority messages if they are preempted by higher priority messages. Lower priority restoration efforts resume upon receipt of a finished status message from the sender node of the higher priority sender-chooser pair.

Abstract: To restore partial outages within a communication network having numerous switching nodes and links interconnecting the nodes, a three-stage distributed restoration protocol is activated to use spare links to bypass failed links and restore normal network connectivity. The three-stage protocol detects and resolves contention for spare resources among separate restoration processes and is therefore particularly advantageous in the event of multiple simultaneous network failures. A conservative flooding approach is used during the first forward signalling stage. Data elements added to the forward signals convey the likelihood that the path will be needed for restoration. The second reverse signalling stage uses reverse signals with attached contention data to detect contention among separate processes for spare resources and to alert the respective processes.

Abstract: A system and method for restoring communications between a pair of nodes, between which communications have been broken, in a network.

Abstract: A system and method for restoration of a disrupted telecommunications path between a source node and a destination node via at least one tandem node. The operation of the present invention proceeds in five phases: notification, broadcast, path trace-out, confirmation and cleanup. In the notification phase, the path's source and destination nodes are notified of the disruption. In the broadcast phase, the network is flooded with PACK messages to locate restoration paths; selective rebroadcasting of the PACK messages limits the volume of restoration message traffic. In the path trace-out phase, bandwidth is conservatively reserved along the restoration paths indicated by the PACK messages. In the confirmation phase, restoration paths are built up step-wise along the traced-out paths, thereby restoring the disrupted path between the source and destination nodes.