Patents by Inventor John David GRAEF

John David GRAEF has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11827695
    Abstract: Disclosed herein are anti-?-synuclein antibodies which preferentially bind to oligomeric ?-synuclein over monomeric ?-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: November 28, 2023
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael K. Ahlijanian, Jere Ernest Meredith, Jr., Nino Devidze, John David Graef, Edward L. Halk
  • Patent number: 11142570
    Abstract: Disclosed herein are anti-?-synuclein antibodies which preferentially bind to oligomeric ?-synuclein over monomeric ?-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: October 12, 2021
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Michael K. Ahlijanian, Jere Ernest Meredith, Jr., Nino Devidze, John David Graef, Edward L. Halk
  • Publication number: 20210221878
    Abstract: Disclosed herein are anti-?-synuclein antibodies which preferentially bind to oligomeric ?-synuclein over monomeric ?-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.
    Type: Application
    Filed: January 19, 2021
    Publication date: July 22, 2021
    Inventors: Michael K. AHLIJANIAN, Jere Ernest MEREDITH, Jr., Nino DEVIDZE, John David GRAEF, Edward L. HALK
  • Publication number: 20200231661
    Abstract: Disclosed herein are anti-?-synuclein antibodies which preferentially bind to oligomeric ?-synuclein over monomeric ?-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.
    Type: Application
    Filed: February 16, 2018
    Publication date: July 23, 2020
    Inventors: Michael K. AHLIJANIAN, Jere Ernest MEREDITH, Jr., Nino DEVIDZE, John David GRAEF, Edward L. HALK