Patents by Inventor John David Hayler

John David Hayler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing 2-(6-(1H-indol-4-yl)-1H-indazol-4-yl)-5-((4-isopropylpiperazin-1-yl)methyl)oxazole
    Patent number: 10266525
    Abstract: The present invention provides novel processes for preparing compounds of formula (IV) and salts thereof novel intermediates, and a novel salt and polymorph thereof.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: April 23, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Robert Nicholas Bream, John David Hayler, Alan Geoffrey Ironmonger, Peter Szeto, Michael Robert Webb, Katherine Marie Penelope Wheelhouse, Robert David Willacy
  • NOVEL PROCESSES
    Publication number: 20180155334
    Abstract: The present invention provides novel processes for preparing compounds of formula (IV) and salts thereof novel intermediates, and a novel salt and polymorph thereof.
    Type: Application
    Filed: May 31, 2016
    Publication date: June 7, 2018
    Inventors: Robert Nicholas BREAM, John David HAYLER, Alan Geoffrey IRONMONGER, Peter SZETO, Michael Robert WEBB, Katherine Marie Penelope WHEELHOUSE, Robert David WILLACY
  • Process for production of naphthyridine-3-carboxylic acid derivatives
    Patent number: 7232907
    Abstract: A process for the production of naphthyridine-3-carboxylic acid derivatives of formula (I) having antibacterial activity.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: June 19, 2007
    Assignee: LG Life Sciences Limited
    Inventors: John David Hayler, Hoon Choi, Sungwook Cho
  • Process for the preparation of diphosphonate derivatives
    Patent number: 6048995
    Abstract: A process for the preparation of a compound of formula I, ##STR1## wherein R.sup.1 and R.sup.2 are independently C.sub.1-6 alkyl, R.sup.3 is hydroxy and R.sup.4 and R.sup.5 are independently C.sub.1-6 alkyl is disclosed. The process comprises reacting a compound of formula II, ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are defined as in formula I and X is a leaving group, with a compound of formula III, ##STR3## wherein R.sup.4 and R.sup.5 are independently C.sub.1-6 alkyl, in the presence of a base.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: April 11, 2000
    Inventors: Trevor John Grinter, John David Hayler, Alan Negus, Michael Anthony Harris
  • Process for preparing benzopyran compounds
    Patent number: 5777128
    Abstract: The present invention relates to a process for preparing compounds of structure (I), and the intermediate compound of formula (II).
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: July 7, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John David Hayler, Trevor John Grinter, Vance Novak, Norman John Lewis