Patents by Inventor John Dowd
John Dowd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11945837Abstract: Methods of enhancing efficiency of downstream chromatography steps for purification of proteins comprising: (a) passing a composition comprising a polypeptide of interest and various contaminants through an ion exchange membrane, wherein the polypeptide and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH sufficiently distinct from the pi of the polypeptide to enhance the charge of the polypeptide and a low ionic strength effective to prevent the shielding of charges by buffer ions, which cause the membrane to bind the polypeptide and at least one contaminant, (b) overloading the ion exchange membrane such that at least one contaminant remains bound to the membrane while the polypeptide of interest is primarily in the effluent; (c) collecting the effluent from the ion exchange membrane comprising the polypeptide of interest; (d) subjecting the membrane effluent comprising the polypeptide of interest to a purification step of similar charge as the previous membrane,Type: GrantFiled: June 6, 2019Date of Patent: April 2, 2024Assignee: Genentech, Inc.Inventors: Jerome Joseph Bill, Jr., Arick Michael Brown, Christopher John Dowd, Brooke Ellen Thayer
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Patent number: 11210933Abstract: An apparatus comprising an irrigation sprinkler body cover with an integrated battery-powered decoder is disclosed. A method of retrofitting existing irrigation systems to wirelessly communicate with one or more of the present apparatus is also disclosed. Concerning the present method, an irrigation controller provides message data to a gateway regarding the control of irrigation valves. The gateway contains configurable encoder software that encodes and then wirelessly transmits the message data, for example via long-range radio hardware at 902-928 MHz frequency. The encoded data is received by a present apparatus to which the message is addressed. The apparatus decodes the message data and subsequently provides a power signal via wire to one or more proximally-located DC latching solenoid valves to control the irrigation valves according to the user input.Type: GrantFiled: June 22, 2020Date of Patent: December 28, 2021Inventors: Jesse Lafian, John Dowd, Ray McLin
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Publication number: 20200320860Abstract: An apparatus comprising an irrigation sprinkler body cover with an integrated battery-powered decoder is disclosed. A method of retrofitting existing irrigation systems to wirelessly communicate with one or more of the present apparatus is also disclosed. Concerning the present method, an irrigation controller provides message data to a gateway regarding the control of irrigation valves. The gateway contains configurable encoder software that encodes and then wirelessly transmits the message data, for example via long-range radio hardware at 902-928 MHz frequency. The encoded data is received by a present apparatus to which the message is addressed. The apparatus decodes the message data and subsequently provides a power signal via wire to one or more proximally-located DC latching solenoid valves to control the irrigation valves according to the user input.Type: ApplicationFiled: June 22, 2020Publication date: October 8, 2020Inventors: Jesse Lafian, John Dowd, Ray McLin
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Publication number: 20200102346Abstract: Methods of enhancing efficiency of downstream chromatography steps for purification of proteins comprising: (a) passing a composition comprising a polypeptide of interest and various contaminants through an ion exchange membrane, wherein the polypeptide and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH sufficiently distinct from the pi of the polypeptide to enhance the charge of the polypeptide and a low ionic strength effective to prevent the shielding of charges by buffer ions, which cause the membrane to bind the polypeptide and at least one contaminant, (b) overloading the ion exchange membrane such that at least one contaminant remains bound to the membrane while the polypeptide of interest is primarily in the effluent; (c) collecting the effluent from the ion exchange membrane comprising the polypeptide of interest; (d) subjecting the membrane effluent comprising the polypeptide of interest to a purification step of similar charge as the previous membrane,Type: ApplicationFiled: June 6, 2019Publication date: April 2, 2020Applicant: Genentech, Inc.Inventors: Jerome Joseph Bill, JR., Arick Michael Brown, Christopher John Dowd, Brooke Ellen Thayer
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Patent number: 10364268Abstract: Methods of enhancing efficiency of downstream chromatography steps for purification of proteins comprising: (a) passing a composition comprising a polypeptide of interest and various contaminants through an ion exchange membrane, wherein the polypeptide and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH sufficiently distinct from the pi of the polypeptide to enhance the charge of the polypeptide and a low ionic strength effective to prevent the shielding of charges by buffer ions, which cause the membrane to bind the polypeptide and at least one contaminant, (b) overloading the ion exchange membrane such that at least one contaminant remains bound to the membrane while the polypeptide of interest is primarily in the effluent; (c) collecting the effluent from the ion exchange membrane comprising the polypeptide of interest; (d) subjecting the membrane effluent comprising the polypeptide of interest to a purification step of similar charge as the previous membrane,Type: GrantFiled: December 18, 2012Date of Patent: July 30, 2019Assignee: Genentech, Inc.Inventors: Jerome Joseph Bill, Jr., Arick Michael Brown, Christopher John Dowd, Brooke Ellen Thayer
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Publication number: 20140348845Abstract: Methods of enhancing efficiency of downstream chromatography steps for purification of proteins comprising: (a) passing a composition comprising a polypeptide of interest and various contaminants through an ion exchange membrane, wherein the polypeptide and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH sufficiently distinct from the pi of the polypeptide to enhance the charge of the polypeptide and a low ionic strength effective to prevent the shielding of charges by buffer ions, which cause the membrane to bind the polypeptide and at least one contaminant, (b) overloading the ion exchange membrane such that at least one contaminant remains bound to the membrane while the polypeptide of interest is primarily in the effluent; (c) collecting the effluent from the ion exchange membrane comprising the polypeptide of interest; (d) subjecting the membrane effluent comprising the polypeptide of interest to a purification step of similar charge as the previous membrane,Type: ApplicationFiled: December 18, 2012Publication date: November 27, 2014Inventors: Jerome Joseph Bill, Jr., Arick Michael Brown, Christopher John Dowd, Brooke Ellen Thayer
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Patent number: 7937263Abstract: The present invention pertains to a system and method for the tokenization of text. The featurizer may be configured to receive input text and convert the input text into tokens. According to one aspect of the invention, the tokens may include only one type of character, the characters selected from the group consisting of letters, numbers, and punctuation. The tokenizer may also include a classifier. The classifier may be configured to receive the tokens from the featurizer. Furthermore, the classifier may be configured to analyze the tokens received from the featurizer to determine if the tokens may be input into a predetermined classification model using a preclassifier. If one of the tokens passes the preclassifier, then the token is classified using the predetermined classification model. Additionally, according to a first aspect of the invention, the tokenizer may also include a finalizer. The finalizer may be configured to receive the tokens and may be configured to produce a final output.Type: GrantFiled: December 1, 2004Date of Patent: May 3, 2011Assignee: Dictaphone CorporationInventors: Jill Carrier, Alwin B. Carus, William F. Cote, John Dowd, Kathryn Del La Femina, Alan Frankel, Wensheng(Vincent) Han, Larissa Lapshina, Bernardo Rechea, Ana Santisteban, Amy J. Uhrbach
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Publication number: 20090193227Abstract: An interface to on-chip memory is described, which provides for using on-chip memory by a RISC superscalar processor, enhanced with methods which execute vector operations by treating the vectors as “streams”, which are fed through one or two function units in a pipelined manner. The interface provides concurrent multiple streams, while at the same time serving “conventional” requests from the host RISC superscalar processor.Type: ApplicationFiled: January 25, 2008Publication date: July 30, 2009Inventor: Martin John Dowd
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Publication number: 20080294552Abstract: A centralized marketplace for efficient and streamlined third party listings, including advertisements, to be placed within networks of marketplaces. An automated backend coordinates the submission of listing transactions, including the collection of fees, timings of display of listings, etc., as well as providing a platform to organize networks. Network organization may occur with user intervention or automatically by the automated backend by specifying a predetermined set of criteria. Each marketplace or marketplace network may facilitate the placement of listings in affiliated marketplaces and similarly receive listings from affiliates for a fee or free.Type: ApplicationFiled: April 30, 2008Publication date: November 27, 2008Applicant: LOOKSMART, LTD.Inventors: Matthew Kaufman, John Dowd, Keith W. Teare
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Publication number: 20080275782Abstract: A centralized marketplace for efficient and streamlined third party listings, including advertisements, to be placed with individuals. Individuals may set terms and fee schedules for accepting listings from advertisers. An automated backend coordinates the listing transactions, including the collection of fees, timings of display of listings, targeting of individuals with desired demographic data, etc., as well as providing a platform to organize networks of individuals. Each individual may facilitate and receive listings from affiliates for a fee or free on devices capable of receiving listings, such as cell phones, personal computers and digital assistants, etc.Type: ApplicationFiled: April 30, 2008Publication date: November 6, 2008Applicant: LOOKSMART, LTD.Inventors: Matthew KAUFMAN, John DOWD, Keith W. TEARE
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Publication number: 20080270909Abstract: Systems and methods to provide premium content over Internet with in place preview. In one embodiment, a method includes: providing a representation of content to a first user, the representation of the content embeddable by the first user into a web page; receiving a request from a browser after the web page having the representation of the content is rendered in the browser; responsive to the request, presenting a user interface to process a payment to access the content without the browser leaving the web page; and upon completion of the payment, presenting the content in the browser.Type: ApplicationFiled: April 23, 2008Publication date: October 30, 2008Applicant: LOOKSMART, LTD.Inventors: Matthew KAUFMAN, John DOWD, Vidar HOKSTAD
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Publication number: 20080172329Abstract: A centralized marketplace for efficient and streamlined third party listings, including advertisements, to be placed within marketplaces. An automated backend coordinates the listing transactions, including the collection of fees, timings of display of listings, etc. Additionally, each marketplace may facilitate the placement of listings in affiliated marketplaces and similarly receive listings from affiliates for a fee or free.Type: ApplicationFiled: January 12, 2007Publication date: July 17, 2008Inventors: Matthew Kaufman, John Dowd, Keith W. Teare
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Publication number: 20060116862Abstract: The present invention pertains to a system and method for the tokenization of text. The featurizer may be configured to receive input text and convert the input text into tokens. According to one aspect of the invention, the tokens may include only one type of character, the characters selected from the group consisting of letters, numbers, and punctuation. The tokenizer may also include a classifier. The classifier may be configured to receive the tokens from the featurizer. Furthermore, the classifier may be configured to analyze the tokens received from the featurizer to determine if the tokens may be input into a predetermined classification model using a preclassifier. If one of the tokens passes the preclassifier, then the token is classified using the predetermined classification model. Additionally, according to a first aspect of the invention, the tokenizer may also include a finalizer. The finalizer may be configured to receive the tokens and may be configured to produce a final output.Type: ApplicationFiled: December 1, 2004Publication date: June 1, 2006Applicant: Dictaphone CorporationInventors: Jill Carrier, Alwin Carus, William Cote, John Dowd, Kathryn Femina, Alan Frankel, Wensheng Han, Larissa Lapshina, Bernardo Rechea, Ana Santisteban, Amy Uhrbach