Abstract: Methods and related systems are described for making measurements at multiple locations in an annular region of a cased sequestration well. A first tool module is positionable within the well and adapted to directly or indirectly measure changing pressure at a first location in the annular region of the well. A pressure change is induced at the first location in the annular region. A second tool module is positionable within the well and adapted to directly or indirectly measure changing pressure at a second location in the annular region. The measured pressure changes at the second location are in response to the induced pressure change at the first location.

Abstract: Methods and related systems are described for making measurements at multiple locations in an annular region of a cased sequestration well. A first tool module is positionable within the well and adapted to directly or indirectly measure changing pressure at a first location in the annular region of the well. A pressure change is induced at the first location in the annular region. A second tool module is positionable within the well and adapted to directly or indirectly measure changing pressure at a second location in the annular region. The measured pressure changes at the second location are in response to the induced pressure change at the first location.

Abstract: Disclosed are methods and compositions for identifying, monitoring and treating premalignant and malignant conditions in a human subject. The present invention further discloses methods and compositions for determining cells undergoing apoptosis, and for increasing the efficacy of a cancer therapy. The methods involve the use of apurinic/apyrimidinic endonuclease (APE), independently, as a marker for (pre)malignant conditions and for apoptosis. Also described are polyclonal antibody preparations for use in methods for detecting APE and methods for modulating expression susceptibility of cells to apoptosis.