Abstract: Provided is a disclosure for a cutting device configured to control a linear speed of a cutting wheel as the cutting wheel gets smaller with use. In one example, the cutting device includes a cutting wheel; an actuator to rotate the cutting wheel; a power source configured to provide power to the actuator for rotating the cutting wheel at an adjustable rotational velocity; and control circuitry configured to adjust the rotational velocity of the cutting wheel to maintain a substantially constant surface speed.

Abstract: Semi-automated or automated manufacturing of micro- or nanostructured identification features on objects and compositions, and especially pharmaceutical compositions. In particular, a motorized stamping apparatus capable of precise hot embossing with or without closed-loop control of the loading; a modular stamp head for a high-throughput parallel stamping apparatus that comprise an array of compact, error-tolerant, individually temperature-controllable stamping elements; inexpensive stamp holders for said elements, as well as associated methods. The inventive features do not reside in the method of making the stamps.

Abstract: An assay device and method of use thereof includes a sample tray comprising a plurality of sample wells having a first volume, and a slide tray comprising a slide, and a liquid dispenser. The slide comprises a plurality of reaction sites on a bottom surface of the slide. The liquid dispenser is configured to dispense a plurality of liquid samples into the sample wells. The sample wells are configured to hold the liquid samples. Each of the liquid samples has a second volume such that the second volume exceeds the first volume and each of the liquid sample sits within and above one of the sample wells. The slide tray and the sample tray are configured such that the slide tray can be placed onto the sample tray, at least one of the reaction sites can be positioned directly above at least one of the sample wells containing a liquid sample, and the liquid sample can be drawn onto the reaction site upon the liquid sample contacting the bottom surface of the slide.

Abstract: To improve anticounterfeiting protection, a method for imprinting pharmaceutical unit compositions comprising: providing a pharmaceutical unit composition, partially coating the exterior of the composition with a coating, stamping the coating with a stamp comprising a plurality of identification features, wherein identification features from the stamp are at least partially transposed in the coating and form a barcode, wherein the plurality of identification features comprise at least one lateral dimension of about 1,000 nm or less. Other objects can be coated and stamped including currency and luxury goods.

Abstract: Semi-automated or automated manufacturing of micro- or nanostructured identification features on objects and compositions, and especially pharmaceutical compositions. In particular, a motorized stamping apparatus capable of precise hot embossing with or without closed-loop control of the loading; a modular stamp head for a high-throughput parallel stamping apparatus that comprise an array of compact, error-tolerant, individually temperature-controllable stamping elements; inexpensive stamp holders for said elements, as well as associated methods. The inventive features do not reside in the method of making the stamps.

Abstract: Improved environmental control system for improved nanolithography, imaging, detecting, and fabricating. An article comprising: at least one environmental chamber; at least one conditioning chamber adapted to be in gaseous communication with the environmental chamber, wherein the conditioning chamber comprises at least one gas transport device such as a fan, optionally at least one temperature probe, and at least one heating-cooling device such as a thermoelectric device which in operation provides a cold side and a hot side, at least one water vapor source, and at least one temperature sensor, at least one humidity sensor, wherein the fan, the thermoelectric device, the water vapor source, the temperature sensor, and the humidity sensor are adapted for a temperature controlled and humidity controlled gaseous flow. Two fans can be used, wherein the fans can transport air in the same direction or in opposite directions.

Abstract: A system for positioning equipment quickly and accurately over a plurality of desired positions by employing a "long move" mode of operation and a "short move" mode of operation to adapt the operation of the positioning system to variable and changing conditions. The system generally includes a microprocessor as the controlling means, a controlled valving means, a pressure source coupled to the valving means, an encoder sensing means and a positioning means defined by a pneumatic cylinder.