Patents by Inventor John E. Cronan, Jr.

John E. Cronan, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autoinducer synthase modulating compounds and uses thereof
    Patent number: 6723321
    Abstract: Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifing modulators of the autoinducer synthesis reaction is also provided. Such modulators are useful for controlling bacterial growth and can be used for therapeutic treatment of bacterial infections particularly in immunocompromised subjects. They are also useful in treating disease states associated with autoinducer synthesis and biofilm development.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: April 20, 2004
    Assignees: The Board of Trustees of the University of Illinois, The University of Iowa Research Foundation
    Inventors: E. Peter Greenberg, John E. Cronan, Jr., Bryce V. Plapp, Matthew R. Parsek
  • Fusion proteins having a site for in vivo post-translation modification and methods of making and purifying them
    Patent number: 5252466
    Abstract: A hybrid DNA sequence encoding a fusion protein comprising: a first DNA sequence which encodes an amino acid sequence that allows for post-translation modification of the fusion protein; and a second DNA sequence joined end to end with the first DNA sequence and in the same reading frame, the second DNA sequence encoding a selected pThe invention described herein was made in the course of work partially funded by Grant No. 2 RO1 AI15650 from the National Institutes of Health, U.S. Department of Health and Human Services. The U.S. government may have rights in this invention.
    Type: Grant
    Filed: May 18, 1990
    Date of Patent: October 12, 1993
    Assignees: Biotechnology Research and Development Corporation, Board of Trustees of the University of Illinois
    Inventor: John E. Cronan, Jr.