Patents by Inventor John E. Cyr

John E. Cyr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chelators for radioactively labeled conjugates comprising a stabilizing sidechain
    Patent number: 7481993
    Abstract: The invention relates to a conjugate PT comprising (a) a peptide P and (b) a targeting moiety T; wherein the peptide P contains from 4 to 20 amino acid residues with optionally a single thiol moiety at the C- or N-terminus replacing one of these amino acid residues, and including a complexing amino acid sequence comprising (iv) a tridentate or tetradentate planar chelator containing a ligand backbone defined by a perimeter containing a single sulfur donor atom, two or three non-sulfur donor atoms, and intervening atoms between the donor atoms; and (v) a stabilizing sidechain comprising a further donor atom, the further donor atom being covalently linked to the ligand backbone of the planar chelator through two or three intervening atoms, provided that said further donor atom is neither the nitrogen nor the oxgen atom of a peptide bond and if said further donor atom is part of a heterocyclic ring, no more than one of the intervening atoms can be part of that ring; and a radioactive metal complexed to t
    Type: Grant
    Filed: March 9, 2006
    Date of Patent: January 27, 2009
    Assignee: Schering AG
    Inventor: John E. Cyr
  • Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
    Patent number: 7351398
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic thioether.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: April 1, 2008
    Assignee: CIS bio international
    Inventors: John E. Cyr, Daniel A. Pearson
  • Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy chromans
    Patent number: 7351397
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic 6-hydroxy-chroman derivative.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: April 1, 2008
    Assignee: CIS bio international
    Inventor: John E. Cyr
  • Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans
    Patent number: 6989138
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a mixture of a hydrophilic thioether and a hydrophilic 6-hydroxy-chroman derivative.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: January 24, 2006
    Assignee: Diatide, Inc.
    Inventors: John E. Cyr, Daniel A. Pearson
  • Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
    Patent number: 6902718
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic thioether.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: June 7, 2005
    Assignee: Diatide, Inc.
    Inventors: John E. Cyr, Daniel A. Pearson
  • Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy-chromans
    Patent number: 6881396
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic 6-hydroxy-chroman derivative.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 19, 2005
    Assignee: Diatide, Inc.
    Inventor: John E. Cyr
  • Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans
    Publication number: 20040058984
    Abstract: Radiopharmaceutical compositions are stabilized by addition of a hydrophilic thioether, a hydrophilic 6-hydroxy-chroman derivative or a mixture of a hydrophilic thioether and a hydrophilic 6-hydroxy-chroman derivative. The preferred thioether is L-methionine. The preferred 6-hydroxy-chroman derivative is 6-hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid.
    Type: Application
    Filed: August 8, 2003
    Publication date: March 25, 2004
    Inventors: John E. Cyr, Daniel A. Pearson
  • Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy-chromans
    Publication number: 20030103899
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic 6-hydroxy-chroman derivative.
    Type: Application
    Filed: April 24, 2002
    Publication date: June 5, 2003
    Inventor: John E. Cyr
  • Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans
    Publication number: 20030103895
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a mixture of a hydrophilic thioether and a hydrophilic 6-hydroxy-chroman derivative.
    Type: Application
    Filed: April 24, 2002
    Publication date: June 5, 2003
    Inventors: John E. Cyr, Daniel A. Pearson
  • Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
    Publication number: 20030072709
    Abstract: Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic thioether.
    Type: Application
    Filed: April 24, 2002
    Publication date: April 17, 2003
    Inventors: John E. Cyr, Daniel A. Pearson