Abstract: The invention provided Mucorales CotH antibodies, polypeptides, encoding nucleic acid molecules, and uses thereof. The Mucorales CotH antibodies, polypeptides and encoding nucleic acids disclosed herein can be advantageously used to diagnose, treat or prevent fungal conditions, in particular mucormycosis.

Abstract: A downhole tool is conveyed within a borehole extending into a subterranean formation. A void is created in a sidewall of the borehole by extending a rotating member from the downhole tool into the sidewall. A portion of the sidewall surrounding the void is mechanically compressed, and the viscosity of hydrocarbons in the subterranean formation proximate the void is reduced by injecting a fluid from the downhole tool into the formation via the void. Fluid comprising the reduced viscosity hydrocarbons and the injected fluid may then be drawn from the subterranean formation into the downhole tool.

Abstract: The invention provided Mucorales CotH antibodies, polypeptides, encoding nucleic acid molecules, and uses thereof. The Mucorales CotH antibodies, polypeptides and encoding nucleic acids disclosed herein can be advantageously used to diagnose, treat or prevent fungal conditions, in particular mucormycosis.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include antibody, antibody fragments, siRNA and vaccine compositions having or directed against a GRP78 polypeptide or an antigenic fragment of the polypeptide.

Abstract: The invention provided Mucorales CotH polypeptides and encoding nucleic acid molecules. The Mucorales CotH polypeptides and encoding nucleic acids can be advantageously used to diagnose, treat or prevent fungal conditions, in particular mucormycosis.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include antibody, antibody fragment, siRNA and vaccine compositions having or directed against a GRP78 polypeptide or an antigenic fragment of the polypeptide.

Abstract: A downhole tool is conveyed within a borehole extending into a subterranean formation. A void is created in a sidewall of the borehole by extending a rotating member from the downhole tool into the sidewall. A portion of the sidewall surrounding the void is mechanically compressed, and the viscosity of hydrocarbons in the subterranean formation proximate the void is reduced by injecting a fluid from the downhole tool into the formation via the void. Fluid comprising the reduced viscosity hydrocarbons and the injected fluid may then be drawn from the subterranean formation into the downhole tool.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include antibody, antibody fragment, siRNA and vaccine compositions having or directed against a GRP78 polypeptide or an antigenic fragment of the polypeptide.

Abstract: The invention is a sealing system, such as a packer, that is used in a wellbore to seal against an exterior surface, such as a casing or open wellbore. The sealing system includes a swellable material that swells from an unexpanded state to an expanded state thereby creating a seal when the swellable material comes into contact with a triggering fluid.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include vaccine compositions having an FTR polypeptide or an antigenic fragment of the polypeptide; a vector including a nucleotide sequence that is substantially complimentary to at least 18 contiguous nucleotides of FTR sequence; an antisense; a small interfering RNA or an antibody inhibitor of FTR. The vaccine compositions of the invention can further include an adjuvant.

Abstract: The invention provided Mucorales CotH polypeptides and encoding nucleic acid molecules. The Mucorales CotH polypeptides and encoding nucleic acids can be advantageously used to diagnose, treat or prevent fungal conditions, in particular mucormycosis.

Abstract: There is provided a method of testing a subterranean formation for fracture condition, including the steps of creating a side bore into the wall of a well traversing the formation, sealing the wall around the side bore to provide a pressure seal between the side bore and the well, pressurizing the side bore beyond a pressure inducing formation fracture while maintaining the seal and monitoring the pressure to identify the fracture condition.

Abstract: There is provided a method of sampling a subterranean formation. The method includes the steps of creating a side bore into the wall of a well traversing the formation, sealing the wall around the side bore to provide a pressure seal between the side bore and the well, pressurizing the side bore beyond a pressure inducing formation fracture while maintaining the seal, pumping a fracturing fluid adapted to prevent a complete closure of the fracture through the side bore into the fracture, and reversing the pumping to sample formation fluid through the fracture and the side bore.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include vaccine compositions having an FTR polypeptide or an antigenic fragment of the polypeptide; a vector including a nucleotide sequence that is substantially complimentary to at least 18 contiguous nucleotides of FTR sequence; an antisense; a small interfering RNA or an antibody inhibitor of FTR. The vaccine compositions of the invention can further include an adjuvant.

Abstract: There is provided a method of testing a subterranean formation for fracture condition, including the steps of creating a side bore into the wall of a well traversing the formation, sealing the wall around the side bore to provide a pressure seal between the side bore and the well, pressurizing the side bore beyond a pressure inducing formation fracture while maintaining the seal and monitoring the pressure to identify the fracture condition.

Abstract: There is provided a method of sampling a subterranean formation, including the steps of creating a side bore into the wall of a well traversing the formation, sealing the wall around the side bore to provide a pressure seal between the side bore and the well, pressurizing the side bore beyond a pressure inducing formation fracture while maintaining the seal, pumping a fracturing fluid adapted to prevent a complete closure of the fracture through the side bore into the fracture, and reversing the pumping to sample formation fluid through the fracture and the side bore.

Abstract: An apparatus includes a base pipe and a fluid control material. The base pipe includes openings, and the fluid control material is mounted to the pipe to control fluid communication through the openings of the pipe. The fluid control material has a permeability that may be changed to selectively control the communication of well fluid through the openings.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include antibody, antibody fragment, siRNA and vaccine compositions having or directed against a GRP78 polypeptide or an antigenic fragment of the polypeptide.

Abstract: The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include vaccine compositions having an FTR polypeptide or an antigenic fragment of the polypeptide; a vector including a nucleotide sequence that is substantially complimentary to at least 18 contiguous nucleotides of FTR sequence; an antisense; a small interfering RNA or an antibody inhibitor of FTR. The vaccine compositions of the invention can further include an adjuvant.

Abstract: The invention is a sealing system, such as a packer, that is used in a wellbore to seal against an exterior surface, such as a casing or open wellbore. The sealing system includes a swellable material that swells from an unexpanded state to an expanded state thereby creating a seal when the swellable material comes into contact with a triggering fluid.