Patents by Inventor John E. Fisher

John E. Fisher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES SPECIFIC FOR DKK-1
    Publication number: 20120201835
    Abstract: Antibodies specific for Dkk-1, an inhibitor of the osteoanabolic Wnt/LRP5 signaling pathway, are described. The antibodies, which inhibit binding of Dkk-1 to LRP5, are useful in compositions for stimulating bone growth, in particular, compositions for treating bone disorders which result in a loss in bone, for example, osteoporosis.
    Type: Application
    Filed: June 27, 2011
    Publication date: August 9, 2012
    Applicant: MERCK
    Inventors: Zhiqiang An, Fang Chen, John E. Fisher, Helmut Glantschnig, Donald B. Kimmel, Alfred A. Reszka, Fubao Wang
  • Antibodies specific for Dkk-1
    Patent number: 7994293
    Abstract: Antibodies specific for Dkk-1, an inhibitor of the osteoanabolic Wnt/LRP5 signaling pathway, are described. The antibodies, which inhibit binding of Dkk-1 to LRP5, are useful in compositions for stimulating bone growth, in particular, compositions for treating bone disorders which result in a loss in bone, for example, osteoporosis.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: August 9, 2011
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Zhiqiang An, Fang Chen, John E. Fisher, Helmut Glantschnig, Donald B. Kimmel, Alfred A. Reszka, Fubao Wang
  • PROCESS FOR PRODUCING NANOPOROUS CARBIDE-DERIVED CARBON WITH INCREASED GAS STORAGE CAPABILITY
    Publication number: 20090301902
    Abstract: Methods for producing and using nanoporous carbide-derived carbon in applications involving gas storage are provided.
    Type: Application
    Filed: June 1, 2006
    Publication date: December 10, 2009
    Inventors: Yury Gogotsi, Gleb Yushin, Ranjan Kumar Dash, John E. Fisher
  • Antibodies specific for DKK-1
    Publication number: 20080193449
    Abstract: Antibodies specific for Dkk-1, an inhibitor of the osteoanabolic Wnt/LRP5 signaling pathway, are described. The antibodies, which inhibit binding of Dkk-1 to LRP5, are useful in compositions for stimulating bone growth, in particular, compositions for treating bone disorders which result in a loss in bone, for example, osteoporosis.
    Type: Application
    Filed: February 6, 2008
    Publication date: August 14, 2008
    Inventors: Zhiqiang An, Fang Chen, John E. Fisher, Helmut Glantschnig, Donald B. Kimmel, Alfred A. Reszka, Fubao Wang
  • Compositions and methods for inhibiting bone resorption
    Publication number: 20040180862
    Abstract: The present invention relates to parenteral compositions and methods for inhibiting bone resorption in a mammal while counteracting potential local irritation at injection sites. The compositions useful herein comprise the combination of a pharmaceutically effective amount of a farnesyl diphosphate synthase inhibiting bisphosphonate or a pharmaceutically-acceptable salt thereof and a pharmaceutically effective amount of a squalene synthase inhibitor.
    Type: Application
    Filed: December 5, 2003
    Publication date: September 16, 2004
    Inventors: Alfred A. Reszka, John E. Fisher
  • Methods of inhibiting bone resorption
    Publication number: 20010025028
    Abstract: The present invention relates to methods of inhibiting bone resorption comprising administering a therapeutically effective amount of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Type: Application
    Filed: April 11, 2001
    Publication date: September 27, 2001
    Applicant: Merck & Co., Inc.
    Inventors: John E. Fisher, Gideon A. Rodan