Patents by Inventor John E. Frye

John E. Frye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pulmonary dosing system and method
    Patent number: 6805118
    Abstract: A pulmonary dosing system and method for supplying to a patient a predetermined amount of respirable therapeutically active material. The system comprises a patient interface to introduce the material into the patient's lungs. The patient interface is connected to a flexible inhalation tube and a flexible exhalation tube. The exhalation tube is connected to a filter having an outlet connected to atmosphere. The inhalation tube is connected to an apparatus for providing pulsed amounts of the material entrained in filtered atmospheric air. A control unit operates the pulmonary dosing system in accordance with operator inputs regarding the number of patent exhales between pulses, and pulse length. The exhaust filter and the apparatus for providing pulsed amounts of the therapeutically active material may be enclosed in a containment case and the patient's interface may comprise a mouth tube-mask combination when the therapeutically active material comprises at least one toxic drug.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: October 19, 2004
    Assignee: Zivena, Inc.
    Inventors: Michael J. Brooker, John E. Frye, Paul T. Kotnik, Michael B. Mosholder, Michael E. Placke, William C. Zimlich, Jr.
  • Formulation and method for treating neoplasms by inhalation
    Publication number: 20020155066
    Abstract: A formulation, method, and apparatus for treating neoplasms such as cancer by administering a pharmaceutically effective amount of highly toxic composition by inhalation, wherein the composition is a non-encapsulated antineoplastic drug.
    Type: Application
    Filed: February 4, 2002
    Publication date: October 24, 2002
    Inventors: Michael E. Placke, Anthony R. Imondi, Michael J. Brooker, John E. Frye, Praful K. Shah, Douglas R. Flanagan, Maureen D. Donovan
  • Pulmonary dosing system and method
    Publication number: 20020026940
    Abstract: A pulmonary dosing system and method for supplying to a patient a predetermined amount of respirable therapeutically active material. The system comprises a patient interface to introduce the material into the patient's lungs. The patient interface is connected to a flexible inhalation tube and a flexible exhalation tube. The exhalation tube is connected to a filter having an outlet connected to atmosphere. The inhalation tube is connected to an apparatus for providing pulsed amounts of the material entrained in filtered atmospheric air. A control unit operates the pulmonary dosing system in accordance with operator inputs regarding the number of patent exhales between pulses, and pulse length. The exhaust filter and the apparatus for providing pulsed amounts of the therapeutically active material may be enclosed in a containment case and the patient's interface may comprise a mouth tube-mask combination when the therapeutically active material comprises at least one toxic drug.
    Type: Application
    Filed: August 2, 2001
    Publication date: March 7, 2002
    Applicant: Battelle Memorial Institute, Inc.
    Inventors: Michael J. Brooker, John E. Frye, Paul T. Kotnik, Michael B. Mosholder, Michael E. Placke, William C. Zimlich
  • Formulation and method for treating neoplasms by inhalation
    Patent number: 6348209
    Abstract: A formulation, method, and apparatus for treating neoplasms such as cancer by administering a pharmaceutically effective amount of highly toxic composition by inhalation, wherein the composition is a non-encapsulated antineoplastic drug.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: February 19, 2002
    Assignee: Battelle Pulmonary Therapeutics, Inc.
    Inventors: Michael E. Placke, Anthony R. Imondi, Michael J. Brooker, John E. Frye, Praful K. Shah, Douglas R. Flanagan, Jr., Maureen D. Donovan
  • Formulation and method for treating neoplasms by inhalation
    Publication number: 20010038827
    Abstract: A formulation, method, and apparatus for treating neoplasms such as cancer by administering a pharmaceutically effective amount of highly toxic composition by inhalation, wherein the composition is a non-encapsulated antineoplastic drug.
    Type: Application
    Filed: June 6, 2001
    Publication date: November 8, 2001
    Inventors: Michael E. Placke, Anthony R. Imondi, Michael J. Brooker, John E. Frye, Praful K. Shah, Douglas R. Flanagan, Maureen D. Donovan
  • Formulation and method for treating neoplasms by inhalation
    Publication number: 20010038826
    Abstract: A formulation, method, and apparatus for treating neoplasms such as cancer by administering a pharmaceutically effective amount of highly toxic composition by inhalation, wherein the composition is a non-encapsulated antineoplastic drug.
    Type: Application
    Filed: June 6, 2001
    Publication date: November 8, 2001
    Inventors: Michael E. Placke, Anthony R. Imondi, Michael J. Brooker, John E. Frye, Praful K. Shah, Douglas R. Flanagan, Maureen D. Donovan
  • Formulation and method for treating neoplasms by inhalation
    Publication number: 20010036444
    Abstract: A formulation, method, and apparatus for treating neoplasms such as cancer by administering a pharmaceutically effective amount of highly toxic composition by inhalation, wherein the composition is a non-encapsulated antineoplastic drug.
    Type: Application
    Filed: June 6, 2001
    Publication date: November 1, 2001
    Inventors: Michael E. Placke, Anthony R. Imondi, Michael J. Brooker, John E. Frye, Praful K. Shah, Douglas R. Flanagan, Maureen D. Donovan
  • Pulmonary dosing system and method
    Patent number: 6269810
    Abstract: A pulmonary dosing system and method for supplying to a patient a predetermined amount of respirable therapeutically active material. The system comprises a patient interface to introduce the material into the patient's lungs. The patient interface is connected to a flexible inhalation tube and a flexible exhalation tube. The exhalation tube is connected to a filter having an outlet connected to atmosphere. The inhalation tube is connected to an apparatus for providing pulsed amounts of the material entrained in filtered atmospheric air. A control unit operates the pulmonary dosing system in accordance with operator inputs regarding the number of patent exhales between pulses, and pulse length. The exhaust filter and the apparatus for providing pulsed amounts of the therapeutically active material may be enclosed in a containment case and the patient's interface may comprise a mouth tube-mask combination when the therapeutically active material comprises at least one toxic drug.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: August 7, 2001
    Assignee: Battelle Memorial Institute
    Inventors: Michael J. Brooker, John E. Frye, Paul T. Kotnik, Michael B. Mosholder, Michael E. Placke, William C. Zimlich, Jr.