Patents by Inventor John E Hodgson

John E Hodgson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Patent number: 7422749
    Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: September 9, 2008
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Michael T. Black, Martin K. Burnham, Jason C. Fedon, John E. Hodgson, David J. Knowles, Michael A. Lonetto, Richard O. Nicholas, Leslie M. Palmer, Julie M. Pratt, Raymond W. Reichard, Martin Rosenberg, Christopher M. Traini, Judith Ward, Richard L. Warren
  • pth
    Publication number: 20020106776
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: June 8, 2001
    Publication date: August 8, 2002
    Inventors: Sanjoy Biswas, Martin K. Burnham, Andrew P. Fosberry, John E. Hodgson, Elizabeth J. Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • defl
    Publication number: 20020058796
    Abstract: The invention provides def1 polypeptides and polynucleotides encoding def1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def1 polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 21, 2001
    Publication date: May 16, 2002
    Inventors: Michael A. Lonetto, David J. Holmes, Deborah D. Jaworski, Richard O. Nicholas, Min Wang, Robert K. Stodola, Anna L. Kosmatka, Richard L. Warren, David J.C. Knowles, Christopher M. Traini, John E. Hodgson
  • ama
    Publication number: 20020052472
    Abstract: The invention provides ama polypeptides and polynucleotides encoding ama polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ama polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: January 12, 2001
    Publication date: May 2, 2002
    Inventors: David T. Beattie, Robert L. Deresiewicz, Adrian M. Lowe, Michael A. Lonetto, John E. Hodgson, Richard O. Nicholas, Leslie Marie Palmer, Julie M. Pratt
  • pth
    Patent number: 6274361
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: August 14, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Sanjoy Biswas, Martin K. R. Burnham, Andrew P. Fosberry, John E Hodgson, Elizabeth J Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • Ribosome recycling factor (FRR) of Staphylococcus aureus
    Patent number: 6238887
    Abstract: This invention provides frr polypeptides and polynucleotides encoding frr polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing frr polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: May 29, 2001
    Assignees: Brigham & Women's Hospital, Virus Research Institute, SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: David T Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson, Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt
  • UDP-N-acetylmuramoyl-l-alanine:D-glutamate ligase (MURD) of staphylococcus aureus
    Patent number: 6211161
    Abstract: The invention provides murD polypeptides and polynucleotides encoding murD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murD polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: April 3, 2001
    Assignees: Brigham & Women's Hospital, Virus Research Institute, SmithKline Beecham Corporation, SmithKline Beecham plc,
    Inventors: David T Beattie, Robert L Deresiewicz, Adrian M Lowe, Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt, Michael A Lonetto, John E Hodgson
  • Ama
    Patent number: 6197549
    Abstract: This invention provides ama polypeptides and polynucleotides encoding ama polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ama polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: March 6, 2001
    Assignees: Brigham & Women's Hospital, Virus Research Institute, SmithKline Beecham Corporation, SmithKline Beecham, plc
    Inventors: Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt, David T. Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson
  • Staphylococcus aureus 3-hydroxyacyl-CoA dehydrogenase
    Patent number: 6146863
    Abstract: The invention provides hcd polypeptides and polynucleotides encoding Staphylococcus aureus 3-hydroxyacyl-CoA dehydrogenase (hcd) polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hod polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: November 14, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Leslie Marie Palmer, Michael A Lonetto, Richard O Nicholas, Robert L Deresiewicz, Julie M Pratt, John E Hodgson, David T Beattie, Adrian M Lowe
  • ClpL
    Patent number: 6126937
    Abstract: The invention provides clpL polypeptides, polynucleotides encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: October 3, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc, Virus Research Institute, Brigham & Women's Hospital
    Inventors: David T Beattie, Robert L Deresiewicz, Adrian M Lowe, Michael A Lonetto, John E Hodgson, Richard O Nicholas, Leslie Marie Palmer, Julie M Pratt
  • DNA molecules and vectors encoding clavulanic acid biosynthesis enzymes
    Patent number: 6037156
    Abstract: DNA sequences obtained from S. clavuligerus, recombinant vectors incorporating such sequences and hosts transformed with such vectors are disclosed. The DNA comprises one or more genes encoding one or more enzymes involved in the biosynthesis of clavulanic acid and may be used to improve the yield of clavulanic acid produced by clavulanic acid-producing organisms such as S. clavuligerus ATCC 27064.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: March 14, 2000
    Assignee: Beecham Group p.l.c.
    Inventors: Ian D. Normansell, John E. Hodgson, Alison J. Earl