Patents by Inventor John E. Humphrey

John E. Humphrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF USING A TGF-beta KNOCKOUT CELL LINE AND COMPOSITIONS RESULTING THEREFROM
    Publication number: 20230143582
    Abstract: This disclosure describes protein compositions including minimal TGF?1 contamination, methods for making those protein compositions, and methods for using those protein compositions. In one aspect, this disclosure describes protein compositions produced by a TGF?1 knockout cell line and methods for using those compositions including, for example, in research or as a therapeutic or prophylactic. In another aspect, this disclosure describes a TGF?1 knockout cell line and methods of making that cell line.
    Type: Application
    Filed: March 23, 2021
    Publication date: May 11, 2023
    Inventors: Anthony D. Person, John E. Humphrey
  • Mammalian expression vectors
    Patent number: 5627033
    Abstract: A vector system that allows the rapid and effective screening of recombinant constructs. The vector system includes a marker protein useful for identifying transfected cell lines, wherein the promoter used to express the marker protein has be substantially weakened in comparison to its corresponding wild type form.
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: May 6, 1997
    Assignee: Research & Diagnostics Systems, Inc.
    Inventors: John M. Smith, John E. Humphrey, Monica L. Tsang, James A. Weatherbee