Patents by Inventor John E. HUNG

John E. HUNG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbial production of cannabinoids
    Patent number: 12522849
    Abstract: The compositions and methods of the disclosure can be used to produce a cannabinoid in a host cell, such as a yeast cell. For example, the disclosure features host cells (e.g., yeast cells) modified to express one or more enzymes of a cannabinoid biosynthetic pathway, such as an acyl activating enzyme (AAE), a tetraketide synthase (TKS), a cannabigerolic acid synthase (CBGaS), and/or an olivetolic acid cyclase (OAC).
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: January 13, 2026
    Assignee: Amyris, Inc.
    Inventors: Victor F. Holmes, John E. Hung, Irina A. Koryakina, Andrew P. Klein, Yi Xiong, William E. Draper, Hailley S. Warbington
  • HIGH EFFICIENCY PRODUCTION OF CANNABIGEROLIC ACID AND CANNABIDIOLIC ACID
    Publication number: 20250002953
    Abstract: The present disclosure features compositions and methods for producing one or more cannabinoids, such as cannabidiolic acid (CBDa) or cannabidiol (CBD), in a host cell, such as a yeast cell, that is genetically modified to express the enzymes of a cannabinoid biosynthetic pathway. Using the compositions and methods of the present invention, the host cell may be genetically modified to express one or more enzymes of a cannabinoid biosynthetic pathway, such as CBDaS. The host cell may be cultured in the medium in the presence of a first cannabinoid, for example CBGa, and incubated for a time sufficient to allow for bioconversion of the first cannabinoid to a second cannabinoid, for example CBDa, by the host cell.
    Type: Application
    Filed: July 11, 2022
    Publication date: January 2, 2025
    Inventors: William E. Draper, John E. Hung, Alex McGill, Victor Holmes
  • HIGH EFFICIENCY PRODUCTION OF CANNABIDIOLIC ACID
    Publication number: 20240344093
    Abstract: The present disclosure features compositions and methods for producing one or more cannabinoids, such as cannabidiolic acid (CBDa), in a host cell, such as a yeast cell, that is genetically modified to express the enzymes of a cannabinoid biosynthetic pathway. Using the compositions and methods of the present invention, the host cell may be genetically modified to express one or more enzymes of a cannabinoid biosynthetic pathway, such as an enzyme having CBDa synthase (CBDaS) activity.
    Type: Application
    Filed: July 11, 2022
    Publication date: October 17, 2024
    Inventors: John E. Hung, William E. Draper, Victor Holmes
  • MICROBIAL PRODUCTION OF CANNABINOIDS
    Publication number: 20230304049
    Abstract: The compositions and methods of the disclosure can be used to produce a cannabinoid in a host cell, such as a yeast cell. For example, the disclosure features host cells (e.g., yeast cells) modified to express one or more enzymes of a cannabinoid biosynthetic pathway, such as an acyl activating enzyme (AAE), a tetraketide synthase (TKS), a cannabigerolic acid synthase (CBGaS), and/or an olivetolic acid cyclase (OAC).
    Type: Application
    Filed: August 19, 2021
    Publication date: September 28, 2023
    Inventors: Victor F. HOLMES, John E. HUNG, Irina A. KORYAKINA, Andrew P. KLEIN, Yi XIONG, William E. DRAPER, Hailley S. WARBINGTON