Abstract: An injection system includes an injection system body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the injection system body, forming a proximal drug and a distal drug chamber. The system further includes a plunger member configured to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a valve forming an openable barrier between the distal needle interface and the distal drug chamber. The valve includes an outer member including a distal diaphragm, and an inner member. The distal diaphragm is configured to elastically deform distally away from the inner member with increased pressure in the distal drug chamber to allow flow from the distal drug chamber to the distal needle interface.

Abstract: A rheology system includes a rheometer including a lower plate and an upper plate, a manipulator including an arm, a loading end effector, a cleaning end effector, and a controller communicatively coupled to the rheometer and the manipulator, the controller including a processor and a computer readable and executable instruction set, which when executed, causes the processor to direct the manipulator to couple the loading end effector to the arm, direct the manipulator engage a specimen with the loading end effector, direct the manipulator to position the specimen on the lower plate of the rheometer, direct the upper plate to engage the specimen between the upper plate and the lower plate, direct the manipulator to couple the cleaning end effector to the arm, and direct the manipulator to engage the lower plate with the cleaning end effector.

Abstract: The present invention provides a novel method for treating osteoporoses, joint and dental diseases and increasing the rate of bone healing by orally administering certain prostaglandins. Further provided are novel compositions employing these prostaglandins.