Abstract: Antisense nucleic acids, compositions and methods are provided for modulating the expression of an amyloid beta protein (A?P) portion of the amyloid precursor protein (APP) coding sequence. The compositions comprise antisense nucleic acids targeted to nucleic acids encoding amyloid precursor protein. Methods of using these nucleic acids for modulation of amyloid precursor protein expression and for treatment of diseases and conditions associated with expression of the amyloid beta protein portion of the amyloid precursor protein are provided.

Abstract: The present application provides methods and compositions for improving cognitive function and enhancing mental performance in subjects, including those suffering from memory deficiencies, by regulating the activity of beta amyloid (A?) in the brain of such subjects.

Abstract: A transfer switch that includes output contacts, primary input contacts, secondary input contacts and a toggle mechanism. The toggle mechanism includes moving contacts that alternately connect the output contacts with the primary and secondary input contacts. The transfer switch includes an actuator that rotates the first crossbar to alternately engage a first set of moving contacts with the output contacts and the primary input contacts, and rotates the second crossbar to alternately engage a second set of moving contacts with the output contacts and the secondary input contacts. A method of actuating a transfer switch to alternate the supply of power to an electric load. The method includes rotating a first crossbar within the transfer switch to engage a first set of switching contacts with a primary power source and rotating a second crossbar within the transfer switch to engage a second set of switching contacts with a secondary power source.

Abstract: An arc chute including a first side wall having a plurality of holes, a second side wall having a plurality of holes and spaced apart from the first side wall, and a plurality of arc chute plates mounted between the first and second side walls. Each of the plurality of arc chute plates include a laterally extending tab on two sides of the arc chute plate, each of the laterally extending tabs being shaped to be interference fitted within one of the plurality of holes. The laterally extending tabs are dimensioned to not substantially extend beyond an outer surface of each of the side walls.

Abstract: A transfer switch that includes output contacts, primary input contacts, secondary input contacts and a toggle mechanism. The toggle mechanism includes moving contacts that alternately connect the output contacts with the primary and secondary input contacts. The transfer switch includes an actuator that rotates the first crossbar to alternately engage a first set of moving contacts with the output contacts and the primary input contacts, and rotates the second crossbar to alternately engage a second set of moving contacts with the output contacts and the secondary input contacts. A method of actuating a transfer switch to alternate the supply of power to an electric load. The method includes rotating a first crossbar within the transfer switch to engage a first set of switching contacts with a primary power source and rotating a second crossbar within the transfer switch to engage a second set of switching contacts with a secondary power source.

Abstract: An arc chute including a first side wall having a plurality of holes, a second side wall having a plurality of holes and spaced apart from the first side wall, and a plurality of arc chute plates mounted between the first and second side walls. Each of the plurality of arc chute plates include a laterally extending tab on two sides of the arc chute plate, each of the laterally extending tabs being shaped to be interference fitted within one of the plurality of holes. The laterally extending tabs are dimensioned to not substantially extend beyond an outer surface of each of the side walls.

Abstract: A transfer switch that absorbs the kinetic energy of a toggle mechanism within the transfer switch just before moving contacts on the toggle mechanism engage a set of stationary contacts. The transfer switch includes output contacts, primary input contacts, secondary input contacts and a toggle mechanism. The toggle mechanism includes moving contacts that alternately connect the output contacts with the primary and secondary input contacts. The transfer switch further includes a dampener that reduces the kinetic energy of the moving contacts before the moving contacts engage the input contacts.

Abstract: An emulation system contains reorganized instruction code sequences for a computer, so that the native code which is used to emulate instructions that occur most frequently in a typical environment are grouped together, to thereby minimize instruction cache conflicts. A representative set of programs which operate with the emulated code are run, and statistics are recorded to determine the most frequently occurring emulated instructions. The native code which emulates these most frequently occurring instructions is then arranged so that the portions of the code are statically stored in main memory at consecutive memory locations. As a result, when the native code for a frequently occurring emulated instruction is loaded from the memory into the cache, the likelihood that the cache will contain the native code for subsequent emulated instructions is maximized, and the likelihood of cache conflicts is minimized.

Abstract: Memory requirements for an emulation system are reduced by generating semantic routines on demand during emulation, rather than statically storing all routines in the body of a software emulation system. The static portion of the emulator code that is loaded into the memory of the computer comprises only one copy of each different type of semantic routine. For the emulated instruction that corresponds to the one routine stored in the emulator code, a dispatch table entry comprises a pointer to the stored semantic routine. The dispatch table entries for the other emulated instructions of the same type comprise pointers to a semantic routine generator for instructions that have the same number of operands. This semantic routine generator locates the statically stored semantic routine and makes a copy of it, substituting the appropriate operands for the desired instruction in place of those in the statically stored routine.

Abstract: The execution time overhead of software emulation is reduced by selecting frequently emulated instruction sequences in the software being emulated, and translating those instruction sequences into the instruction set of the emulating processor. In a first phase, frequently repeated sequences of emulated computer code are identified and selected for translation. In a second phase, the selected sequences from the instruction set of the emulated processor are translated into equivalent sequences for the instruction set of the emulating processor. In a third phase, the instruction sequence of the emulating processor is executed in lieu of emulating the original instructions from the emulated software.