Patents by Inventor John E. Nash

John E. Nash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11707619
    Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: July 25, 2023
    Assignee: Lungpacer Medical Inc.
    Inventors: Viral S. Thakkar, Joaquin Andres Hoffer, Bao Dung Tran, Douglas G. Evans, John E. Nash
  • Publication number: 20230159881
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Application
    Filed: January 9, 2023
    Publication date: May 25, 2023
    Inventors: John E. NASH, William T. FISHER, Gino BRADICA
  • Patent number: 11549094
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: January 10, 2023
    Assignee: DSM IP ASSETS B.V.
    Inventors: John E. Nash, William T. Fisher, Gino Bradica
  • Publication number: 20220031925
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Application
    Filed: October 14, 2021
    Publication date: February 3, 2022
    Inventors: John E. NASH, William T. FISHER, Douglas G. EVANS
  • Patent number: 11167292
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: November 9, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: John E. Nash, William T. Fisher, Douglas G. Evans
  • Publication number: 20210093858
    Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.
    Type: Application
    Filed: October 14, 2020
    Publication date: April 1, 2021
    Applicant: Lungpacer Medical Inc.
    Inventors: Viral S. THAKKAR, Joaquin Andres HOFFER, Bao Dung TRAN, Douglas G. EVANS, John E. NASH
  • Publication number: 20200299632
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Application
    Filed: June 5, 2020
    Publication date: September 24, 2020
    Inventors: John E. NASH, William T. FISHER, Gino BRADICA
  • Publication number: 20200222915
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Application
    Filed: March 30, 2020
    Publication date: July 16, 2020
    Inventors: John E. NASH, William T. FISHER, Douglas G. EVANS
  • Patent number: 10711239
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: July 14, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: John E. Nash, William T. Fisher, Gino Bradica
  • Patent number: 10646884
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: May 12, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: John E. Nash, William T. Fisher, Douglas G. Evans
  • Patent number: 10517633
    Abstract: A device suitable for removing material from a living being is provided, featuring at least an aspiration pump, powered by a motor. The aspiration pump and any optional infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. The helical pumping mechanism may be a helical coiled wire about a central core tube. The helical coil wire, whether together with, or independent of, the core tube, may be rotated to cause a pumping action. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal.
    Type: Grant
    Filed: September 16, 2017
    Date of Patent: December 31, 2019
    Assignee: THE SPECTRANETICS CORPORATION
    Inventors: John E. Nash, Greg Walters, Dennis M. Sauro, Mark Eberhardt, William T. Fisher, Douglas G. Evans
  • Publication number: 20190232056
    Abstract: This disclosure describes, among other embodiments, a catheter. The catheter may include an outer layer defining a plurality of apertures therethrough, and a body defining at least one longitudinal lumen therein. The body may be within the outer layer, and the apertures may be radially outward of the lumen. The catheter may also include a plurality of electrodes positioned in or on the catheter, with each electrode being electrically exposed through an aperture of the plurality of apertures. A ribbon cable may extend through the lumen and include a plurality of leads, with the plurality of leads being electrically connected to the plurality of electrodes. The plurality of leads and electrodes may be formed by the deposition of conductive inks or paints, or by the electrodeposition of copper or other conductive metals or materials.
    Type: Application
    Filed: April 9, 2019
    Publication date: August 1, 2019
    Applicant: Lungpacer Medical Inc.
    Inventors: John E. NASH, Douglas G. EVANS, Viral S. THAKKAR
  • Patent number: 10293164
    Abstract: A catheter may include an outer layer defining a plurality of apertures therethrough, and a body defining at least one longitudinal lumen therein. The body may be within the outer layer, and the apertures may be radially outward of the lumen. The catheter may also include a plurality of electrodes positioned in or on the catheter, with each electrode being electrically exposed through an aperture of the plurality of apertures. A ribbon cable may extend through the lumen and include a plurality of leads, with the plurality of leads being electrically connected to the plurality of electrodes. The plurality of leads and electrodes may be formed by the deposition of conductive inks or paints, or by the electrodeposition of copper or other conductive metals or materials.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: May 21, 2019
    Assignee: Lungpacer Medical Inc.
    Inventors: John E. Nash, Douglas G. Evans, Viral Thakkar
  • Publication number: 20180369581
    Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.
    Type: Application
    Filed: June 29, 2018
    Publication date: December 27, 2018
    Applicant: Lungpacer Medical Inc.
    Inventors: Viral S. THAKKAR, Joaquin Andres HOFFER, Bao Dung TRAN, Douglas G. EVANS, John E. NASH
  • Publication number: 20180339156
    Abstract: A catheter may include an outer layer defining a plurality of apertures therethrough, and a body defining at least one longitudinal lumen therein. The body may be within the outer layer, and the apertures may be radially outward of the lumen. The catheter may also include a plurality of electrodes positioned in or on the catheter, with each electrode being electrically exposed through an aperture of the plurality of apertures. A ribbon cable may extend through the lumen and include a plurality of leads, with the plurality of leads being electrically connected to the plurality of electrodes. The plurality of leads and electrodes may be formed by the deposition of conductive inks or paints, or by the electrodeposition of copper or other conductive metals or materials.
    Type: Application
    Filed: May 26, 2017
    Publication date: November 29, 2018
    Applicant: Lungpacer Medical Inc.
    Inventors: John E. NASH, Douglas G. EVANS, Viral THAKKAR
  • Patent number: 10125345
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: November 13, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: John E. Nash, William T. Fisher, Gino Bradica
  • Publication number: 20180230418
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Application
    Filed: April 10, 2018
    Publication date: August 16, 2018
    Inventors: John E. Nash, William T. Fisher, Gino Bradica
  • Patent number: 9987638
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: June 5, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: John E. Nash, William T. Fisher, Douglas G. Evans
  • Publication number: 20180104703
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Application
    Filed: December 14, 2017
    Publication date: April 19, 2018
    Inventors: John E. Nash, William T. Fisher, Douglas G. Evans
  • Publication number: 20180000510
    Abstract: A device suitable for removing material from a living being is provided, featuring at least an aspiration pump, powered by a motor. The aspiration pump and any optional infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. The helical pumping mechanism may be a helical coiled wire about a central core tube. The helical coil wire, whether together with, or independent of, the core tube, may be rotated to cause a pumping action. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal.
    Type: Application
    Filed: September 16, 2017
    Publication date: January 4, 2018
    Inventors: John E. NASH, Greg WALTERS, Dennis M. SAURO, Mark EBERHARDT, William T. FISHER, Douglas G. EVANS