Abstract: The present invention relates to the field of medical treatment of diseases and disorders, as well as the field of biomedical engineering. Embodiments of the invention relate to the delivery of Irreversible Electroporation (IRE) through the vasculature of organs to treat tumors embedded deep within the tissue or organ, or to decellularize organs to produce a scaffold from existing animal tissue with the existing vasculature intact. In particular, methods of administering non-thermal irreversible electroporation (IRE) in vivo are provided for the treatment of tumors located in vascularized tissues and organs. Embodiments of the invention further provide scaffolds and tissues from natural sources created using IRE ex vivo to remove cellular debris, maximize recellularization potential, and minimize foreign body immune response. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation.

Abstract: The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.

Abstract: A workpiece presenter for fixturing a workpiece of a vehicle assembly is provided, including a platform 50, and a tooling plate 7 removably connected to the platform, the tooling plate including a planar body 10 for supporting fixture tools 32, 34 holding the workpiece and including a connector mechanism to allow the planar body 10 to be removably connected with the platform 50 and the tooling plate having a locater mechanism 70, 72, 74 to locate the planar body 10 with respect to the platform 50 in a repeatable manner.

Abstract: A tooling plate to fixture a workpiece for a vehicle subassembly is provided, including a planar body 10 for supporting fixture tools 32, 34 for holding a workpiece, a connector mechanism to allow the planar body 10 to be removably connected with a workpiece presenter 50, and a locater mechanism 70, 72, 74 to locate the planar body 10 with respect to the workpiece presenter 50 in a repeatable manner.

Abstract: An automotive vehicle is provided having a body being assembled by a joining process line from a plurality of workpieces joined into a plurality of subassemblies according to the steps of providing templates arranged in a predetermined alignment to form a process line, with each template being generated from a defined set of standardized task stations which are operative to perform a joining process on a workpiece of the subassemblies, fixturing workpieces in a workpiece presenter provided in the task stations, at least one workpiece presenter including a tooling plate removably connected and precision located on a platform of a workpiece presenter, and sequentially joining the workpieces together to form the body.

Abstract: A workpiece presenter for fixturing a workpiece of a vehicle assembly is provided, including a platform 50, and a tooling plate 7 removably connected to the platform, the tooling plate including a planar body 10 for supporting fixture tools 32, 34 holding the workpiece and including a connector mechanism to allow the planar body 10 to be removably connected with the platform 50 and the tooling plate having a locater mechanism 70, 72, 74 to locate the planar body 10 with respect to the platform 50 in a repeatable manner.

Abstract: A tooling plate to fixture a workpiece for a vehicle subassembly is provided, including a planar body 10 for supporting fixture tools 32, 34 for holding a workpiece, a connector mechanism to allow the planar body 10 to be removably connected with a workpiece presenter 50, and a locater mechanism 70, 72, 74 to locate the planar body 10 with respect to the workpiece presenter 50 in a repeatable manner.

Abstract: An automotive vehicle is provided having a body being assembled by a joining process line from a plurality of workpieces joined into a plurality of subassemblies according to the steps of providing templates arranged in a predetermined alignment to form a process line, with each template being generated from a defined set of standardized task stations which are operative to perform a joining process on a workpiece of the subassemblies, fixturing workpieces in a workpiece presenter provided in the task stations, at least one workpiece presenter including a tooling plate removably connected and precision located on a platform of a workpiece presenter, and sequentially joining the workpieces together to form the body.

Abstract: A framing system having upright stands on opposite sides of a vehicle body support. Welding fixtures are mounted on the stands having welding tools for performing welding operations on a vehicle body. The stands are supported for linear movement toward and away from an operative position adjacent the vehicle body support. Loaders are provided for transferring fixtures to and from the stands.

Abstract: An incinerator is provided having an extended length of tubing, preferably coiled, and immersed within a bath of molten salt. Means are provided for introducing sludge at a controlled rate along with hot air under pressure for carrying the sludge through the immersed length of tubing, the air and the heat supplied from the molten salt bath causing concurrent drying and burning of the sludge. The exhausted gases are further oxidized by passing them through a portion of the molten salt bath, while solids are separated out and removed.