Abstract: Methods, systems, and devices for adjusting a refresh rate during a self-refresh state are described. A memory system may enter a self-refresh state and execute a first set of refresh operations on a set of rows of memory cells at the memory system according to a first rate. The memory system may determine, based on executing the first set of refresh operations, that a counter associated with the set of refresh operations satisfies a threshold for a second time while the memory system is in the self-refresh state. In response to the counter satisfying the threshold for the second time, a flip-flop circuit at the memory system may modify an output of the flip-flop circuit and the memory system may decrease the rate for executing the refresh operations to a second rate based on the modified output of the flip-flop circuit.

Abstract: An ultrasonic instrument includes a body, an actuation assembly, a shaft assembly, and an end effector. The actuation assembly includes an activation member that is operable to move in a first direction to select a mode of operation. The shaft assembly extends distally from the body and includes an acoustic waveguide. The end effector includes an ultrasonic blade that is in acoustic communication with the acoustic waveguide. The activation member is operable to move in a second direction to activate the end effector in a mode of operation selected by movement of the activation member in the first direction.

Abstract: The disclosed methods, systems, and kits provide the ability to deliver entire clean sheet designs from concept to first hot fire in under six weeks with instant specific impulses above 330 seconds in some of our engines. In examples, thrusters can be delivered that are at less than half of the mass budget allowable for them and they can be delivered in weeks.

Abstract: Systems, methods and devices are provided for facilitating undisturbed performance during service handover thresholds. Methods include monitoring performance parameters over time for multiple types of wireless devices experiencing a handover triggering event and storing the performance parameters for the multiple types of wireless devices. The methods further include analyzing the stored performance parameters for the multiple types of wireless devices to formulate a handover plan for the multiple types of wireless devices. The method further includes generating the handover plan for the multiple types of wireless devices and utilizing the handover plan to determine whether handover default settings should be utilized or overridden.

Abstract: A surgical instrument, has an end effector that includes an ultrasonic blade, and a clamp arm that moves relative to the ultrasonic blade from an opened position toward an intermediate position and a closed position. The clamp arm is offset from the ultrasonic blade to define a predetermined gap in the intermediate position between the opened position and the closed position. A clamp arm actuator connects to the clamp arm and moves from an opened configuration to a closed configuration to direct the clamp arm from the opened position toward the intermediate position and the closed position. A spacer connects with the clamp arm to inhibit movement of the clamp arm from the intermediate position toward the closed position for maintaining the predetermined gap between the clamp arm and the ultrasonic blade.

Abstract: An apparatus includes a body, a shaft, a stapling head assembly, and an anvil. The body includes a motor, a first user input feature, and a second user input feature. The first user input feature is operable to activate the motor. The shaft extends distally from the body. The stapling head assembly is positioned at a distal end of the shaft. The stapling head assembly includes an anvil coupling feature, at least one annular array of staples, and a staple driver. The second user input feature is operable to drive the anvil coupling feature longitudinally. The staple driver is operable to drive the at least one annular array of staples. The motor is operable to drive the staple driver. The anvil is configured to couple with the anvil coupling feature. The anvil is further configured to deform the staples driven by the staple driver.

Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A shingle comprises an overlay, an underlay, and a height increasing material disposed between the overlay and the underlay. The height increasing material includes a first adhesive adhered to the overlay, height increasing granules adhered to the first adhesive, and a second adhesive adhered to the height increasing granules and the underlay. The height increasing material can extend along front ends of tab portions of the overlay, along front cutout edges that extend between tab portions of the overlay, or both.

Abstract: A reactor furnace for coating fiber tow includes an elongate reactor having a fiber tow inlet and a fiber tow outlet; a thermo-chemical reactor section positioned along the elongate reactor; a first microwave source for directing microwave energy along the reactor from a first end of the reactor toward a second end of the reactor; a second microwave source for directing microwave energy along the reactor from the second end of the reactor toward the first end of the reactor; a gas inlet upstream of the thermo-chemical reactor; and a gas outlet downstream of the thermo-chemical reactor.

Abstract: A conducted electrical weapon (“CEW”) comprises one or more mechanisms for receiving, aligning, and maintaining a position of a magazine within a bay of the CEW. Bias spring and datums may be used to align the magazine to be coupled to the CEW, wherein bias springs are configured to apply pressure to push the magazine to interact with datums to align the magazine. A spring and ramp mechanism may be used to maintain a position of the magazine coupled to the bay of the CEW. Respective grades of a locking ramp and a release ramp are used to lock a spring in place when a magazine is coupled to the bay of the CEW.

Abstract: A compound having the following structure of Formula (I): or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R5, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.

Abstract: A grinding head unit mountable in a planetary disk of a surface grinding machine generally including a housing mountable on the planetary disk, a holder supported on the housing and a surface grinding member detachably connectable to the holder wherein the holder is provided with a recess and the holder is provided with a portion receivable within such recess.

Abstract: A surface grinding machine generally consisting of a drive means provided with an output shaft; a planetary disk mounted on the shaft; and at least two grinding head units mounted on the planetary disk, each including a housing mounted on the planetary disk, a shaft having a flange portion, journaled in the unit housing, resilient means interposed between the housing and the flange portion of the unit shaft and a disk provided with a grit surface disposed on an outer side of the flange portion of the unit shaft.

Abstract: A grinding head unit mountable in a planetary disk of a surface grinding machine generally including a housing mountable on the planetary disk, a holder supported on the housing and a surface grinding member detachably connectable to the holder wherein the holder is provided with a recess and the holder is provided with a portion receivable within such recess.

Abstract: A surface grinding machine generally consisting of a drive means provided with an output shaft; a planetary disk mounted on the shaft; and at least two grinding head units mounted on the planetary disk, each including a housing mounted on the planetary disk, a shaft having a flange portion, journaled in the unit housing, resilient means interposed between the housing and the flange portion of the unit shaft and a disk provided with a grit surface disposed on an outer side of the flange, portion of the unit shaft.

Abstract: A power-efficient, distributed reconfigurable computing system and method are provided. A reconfigurable computing system may include an embedded controller for performing real-time control and initialization and circuitry that supports data-flow driven execution of processing phases. The circuitry may include processing elements such as RAM-based field programmable gate array devices and direct memory access engines. The processing elements can be configured for one or more functions or operations of a program and then reconfigured for other functions or operations of the program. The processing elements can be configured or reconfigured to construct a desired sequence of operations in real-time. A processing element may be divided into slots, each of which includes a substantially similar amount of resources. A processing element includes one or more wrappers, and a wrapper may occupy a slot or a group of slots. Layered software architecture separates control software from implementation software.

Abstract: A sighting device may be used to identify and/or locate remote celestial and/or terrestrial objects. The device may include one or more gravity sensors and one or more magnetic sensors that are used to determine the direction in which the device is aimed. Once the aiming direction is determined, a device control system may be used to access an object database and determine a likely candidate object on or near the aiming direction. The device may include capability to output audiovisual information related to the object. The device may be configured to provide audiovisual commands that direct the user to point the device toward a desired or target location, thereby allowing the user to locate objects with unknown positions. The device may be used as a control system for telescopes and other optical devices.

Abstract: A fully automated telescope system is able to be fully operable in both Alt-Az and polar configurations. In either configuration, the telescope aligns itself to the celestial coordinate system following a simplified initialization procedure during which the telescope tube is first pointed north and then pointed towards a user's horizon. A command processor, under application software program control orients the telescope system with respect to the celestial coordinate system given the initial directional inputs. The initial telescope orientation may be further refined by initially inputting a geographical location indicia, or by shooting one or two additional celestial objects. Once the telescope's orientation with respect to the celestial coordinate system is established, the telescope system will automatically move to and track any desired celestial object without further alignment invention by a user.

Abstract: A fully automated telescope system is able to be fully operable in both Alt-Az and polar configurations. In either configuration, the telescope aligns itself to the celestial coordinate system following a simplified initialization procedure during which the telescope tube is first pointed north and then pointed towards a user's horizon. A command processor, under application software program control orients the telescope system with respect to the celestial coordinate system given the initial directional inputs. The initial telescope orientation may be further refined by initially inputting a geographical location indicia, or by shooting one or two additional celestial objects. Once the telescope's orientation with respect to the celestial coordinate system is established, the telescope system will automatically move to and track any desired celestial object without further alignment invention by a user.

Abstract: A telescope system facilitates easy upgrading from friction lock mounting to manual worm drive, and from manual worm drive to motor drive. Vibration isolation provides a steady field of view for enhanced observation and photography. A telescope mount facilitates enhanced below the horizon and zenith viewing. A tripod has detents which hold the legs thereof in a deployed position during handling of the tripod. A cam lock reliably maintains a desired length of telescoping tripod legs.