Abstract: Systems and methods are provided for improving the flight safety of fixed- and rotary-wing unmanned aerial systems (UAS) operating in complex dynamic environments, including urban cityscapes. Sensors and computations are integrated to predict local winds and promote safe operations in dynamic urban regions where GNSS and other network communications may be unavailable. The system can be implemented onboard a UAS and does not require in-flight communication with external networks. Predictions of local winds (speed and direction) are created using inputs from sensors that scan the local environment. These predictions are then used by the UAS guidance, navigation, and control (GNC) system to determine safe trajectories for operations in urban environments.