Patents by Inventor John EARNEY
John EARNEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240118203Abstract: The motion of a mechanical stage may be directed in x-, y-, and/or z-dimensions such that excitation of a resonant frequency f is reduced. In particular, once a resonant frequency f is identified, the acceleration of the stage in the x-, y-, and/or z-dimensions may divided into an even number of acceleration segments or intervals, with the second of each pair of acceleration segments starting 1/(2f) seconds after the start of the initial acceleration segment. The acceleration intervals may be defined by a start time, an amplitude profile, and/or a time duration. In some implementations, the amplitude and time duration of each acceleration pulse may be different. The amplitude and time duration of acceleration steps may be determined and adjusted to compensate for the particular resonance frequency of an individual system, and programmed into a controller for the stage using motor programming controls.Type: ApplicationFiled: September 27, 2023Publication date: April 11, 2024Applicant: Illumina, Inc.Inventors: Shavinesh Sukesh, Chia-Hsi Liu, Gregory Holst, Ahmed Okasha, Kurt Danielson, John Earney
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Publication number: 20240109063Abstract: An apparatus includes a flow cell, an imaging assembly, and a processor. The flow cell includes a channel and a plurality of reaction sites. The imaging assembly is operable to receive light emitted from the reaction sites in response to an excitation light. The processor is configured to drive relative movement between at least a portion of the imaging assembly and the flow cell along a continuous range of motion to thereby enable the imaging assembly to capture images along the length of the channel. The processor is also configured to activate the imaging assembly to capture one or more calibration images of one or more calibration regions of the channel, during a first portion of the continuous range of motion. The processor is also configured to activate the imaging assembly to capture images of the reaction sites during a second portion of the continuous range of motion.Type: ApplicationFiled: September 28, 2023Publication date: April 4, 2024Inventors: Dustin BLAIR, Patrick WEN, John EARNEY, Anmiv PRABHU, Rachel ABASKHARON, Gregory HOLST, Chia-Hsi LIU, Ravi THAKUR, Dakota WATSON, Kevin BARTIG, Daeyong SIM
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Publication number: 20240114243Abstract: Some implementations of the disclosure relate to an imaging system including one or more image sensors and a Z-stage. The imaging system is configured to perform operations including: capturing, using the one or more image sensors, a first image of a first pair of spots projected at a first sample location of a sample; determining whether or not the first image of the first pair of spots is valid; and when the first image is determined to be valid: obtaining, based on the first image, a current separation distance measurement of the first pair of spots; and controlling, based at least on the current separation distance measurement, the Z-stage to focus the imaging system at the first sample location.Type: ApplicationFiled: September 25, 2023Publication date: April 4, 2024Inventors: Yu Chen, Gregory Holst, John Earney, Patrick Wen, Chia-Hsi Liu, Daeyong Sim
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Publication number: 20240100518Abstract: The presently described techniques relate generally to providing motion feedback (e.g., motion system calibration and/or sample alignment) in the context of an imaging system (such as a time delay and integration (TDI) based imaging system). The architecture and techniques discussed may achieve nanoscale control and calibration of a movement feedback system without a high-resolution encoder subsystem or, in the alternative embodiments, with a lower resolution (and correspondingly less expensive) encoder subsystem than might otherwise be employed. By way of example, certain embodiments described herein relate to ascertaining or calibrating linear motion of a sample holder surface using nanoscale features (e.g., sample sites or nanowells or lithographically patterned features) provided on a surface of the sample holder.Type: ApplicationFiled: September 26, 2023Publication date: March 28, 2024Inventors: Matthew Hage, John Earney, Gregory Holst, Mark Majette
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Publication number: 20230272837Abstract: An apparatus includes a chassis, a frame, a sample support member, an imaging assembly, an actuation assembly, and a vibration capture assembly. The frame is coupled with the chassis. The sample support member is supported by the frame. The actuation assembly is supported by the frame and is operable to drive movement of the imaging assembly relative to the sample support member. The vibration capture assembly is operable to selectively transition between a plurality of modes, including a damping mode and an isolation mode. In the damping mode, the vibration capture assembly is configured to resist movement of the frame relative to the chassis in response to operation of the actuation assembly. In the isolation mode, the vibration capture assembly is configured to prevent transmission of vibrational movement in the chassis to the frame.Type: ApplicationFiled: February 24, 2023Publication date: August 31, 2023Inventors: Gregory Holst, Dustin Blair, John Earney, Geraint Evans, Matthew Hage
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Publication number: 20230228984Abstract: Some implementations of the disclosure relate to an imaging system, including: a sample holder to support a sample container having multiple sample locations; an optical stage having; an assembly comprising one or more actuators physically coupled to the sample holder to tilt the sample holder relative to the optical stage during imaging of the multiple sample locations to focus the optical stage onto a current sample location; a first light source to project a first pair of spots on the sample container; and a controller to control, based on a sample tilt determined from a first separation measurement of the first pair of spots from one or more images taken by an image sensor at one or more of the sample locations, the one or more actuators to tilt the sample holder along a first direction of the imaging or a second direction substantially perpendicular to the first direction.Type: ApplicationFiled: January 17, 2023Publication date: July 20, 2023Inventors: Dakota Watson, Merek Siu, Dustin Blair, Danilo Condello, John Earney, Paul Sangiorgio
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Publication number: 20230201825Abstract: Systems and related temperature calibration methods. In accordance with a first implementation, an apparatus includes a flow cell interface, a temperature control device, an infrared sensor, and a controller. The flow cell interface includes a flow cell support and the temperature control device is for the flow cell support. The controller is to command the temperature control device to cause the flow cell support to achieve a temperature value, cause the infrared sensor to measure an actual temperature value of the flow cell support, and calibrate the temperature control device based on a difference between the commanded temperature value and the actual temperature value.Type: ApplicationFiled: December 21, 2022Publication date: June 29, 2023Inventors: Dustin Blair, Xiangxiong Chen, Gabriel Chan, Bindya Rani Dhanekula, John Earney, Damian Kelley
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Patent number: 10005083Abstract: Provided is an inspection apparatus including: (a) a translucent or transparent plate having a bottom surface, at least a portion of the bottom surface having an opaque material printed thereon in a pattern having at least one transparent or translucent portion; and (b) a chamber disposed below the bottom surface, whereby light emitted from the chamber or through the chamber can pass through the at least one transparent or translucent portion.Type: GrantFiled: December 18, 2016Date of Patent: June 26, 2018Assignee: ILLUMINA, INC.Inventors: John Earney, Dakota Watson, Joseph Pinto
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Publication number: 20170151565Abstract: Provided is an inspection apparatus including: (a) a translucent or transparent plate having a bottom surface, at least a portion of the bottom surface having an opaque material printed thereon in a pattern having at least one transparent or translucent portion; and (h) a chamber disposed below the bottom surface, whereby light emitted from the chamber or through the chamber can pass through the at least one transparent or translucent portion.Type: ApplicationFiled: December 18, 2016Publication date: June 1, 2017Applicant: Illumina, Inc.Inventors: John Earney, Dakota Watson, Joseph Pinto
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Patent number: 9540690Abstract: Provided is an inspection apparatus including: (a) a translucent or transparent plate having a bottom surface, at least a portion of the bottom surface having an opaque material printed thereon in a pattern having at least one transparent or translucent portion; and (b) a chamber disposed below the bottom surface, whereby light emitted from the chamber or through the chamber can pass through the at least one transparent or translucent portion.Type: GrantFiled: August 28, 2014Date of Patent: January 10, 2017Assignee: Illumina, Inc.Inventors: John Earney, Dakota Watson, Joseph Pinto
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Publication number: 20160160276Abstract: Provided is an inspection apparatus including: (a) a translucent or transparent plate having a bottom surface, at least a portion of the bottom surface having an opaque material printed thereon in a pattern having at least one transparent or translucent portion; and (b) a chamber disposed below the bottom surface, whereby light emitted from the chamber or through the chamber can pass through the at least one transparent or translucent portion.Type: ApplicationFiled: August 28, 2014Publication date: June 9, 2016Inventors: John EARNEY, Dakota WATSON, Joseph PINTO