Abstract: (R)-5-Methyl-4,5-dihydro-pyrazole-1,5-dicarboxylic acid 1-[(4-chloro-phenyl)-amide] 5-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} pharmaceutical compositions, methods and methods of using the compound or pharmaceutical compositions thereof to treat diseases characterized by abnormal thrombosis in mammals.

Abstract: Provided are a computer program, method and system providing simplified administration of groups of computer programs. Command target qualifiers are defined which enable a command to be targeted at either an individual computer program or all members of a group of computer programs. Additionally, scope parameters are defined which enable a command to be targeted at specific computer system resources managed by the computer programs within the group. The computer system resources which are to be accessible to all members of a group have an associated scope parameter defining shared or group access and are held in shared storage, whereas computer system resources to be accessed by only one computer program in the group have a corresponding scope parameter and are held in the local storage of the individual computer program.

Abstract: A one component adhesive composition is provided, which can be formulated from substantially or totally bio-based, renewable raw materials. Such adhesives can be formulated to have high strength and/or low or substantially no VOC emissions. This can be achieved by utilizing polymers that are derived or extracted from renewable plant materials such as soybeans, corn, sunflowers, wheat, etc. Adhesive compositions in accordance with the invention can include oils. The composition preferably contains bio-based oils only, but need not be completely free of fossil fuel or synthetic based oils. It should also include drying oils and/or similarly acting polymers, co-polymers, and fatty acids. Plasticizers, such as hydrogen oxide, derived from renewable sources are utilized to impart performance properties to the formulated adhesive. Metal napthanates can be used to catalyze the drying and/or curing speed when the adhesive composition is applied to a substrate.

Abstract: An adaptation to a vehicle antilock braking system modulator to increase the initial displacement of the master cylinder, provide quicker system response and improved pedal feel. A solenoid assembly is added to the non fluid side of each of the low pressure accumulators in the ABS modulator. Upon the operator initiation of a brake apply, the solenoids are energized to immediately push upon the sump pistons and inject fluid from the low pressure accumulators into the brake system. This extra “shot” of fluid decreases the amount of fluid that the master cylinder delivers to the brake system. This improves pedal feel as it reduces the required initial pedal travel for a given brake system displacement. The low pressure accumulator pistons are spring balanced to ensure retention of fluid between brake applies and to allow normal ABS operation. During ABS operation, the low pressure accumulator displacer solenoids are de-energized to allow effective operation.

Abstract: A composition and method which exhibits enhanced moisture sealing properties, suitable for use with flooring materials, such as concrete, and flooring installations, such as carpeting, wood, tiles, etc. are provided. The composition is preferably non-water-based and can form a non-aqueous barrier coating on the flooring substrate, and most preferably provides a desirable pH and blocks migration of alkaline salts through the substrate.

Abstract: A lever for moving first and second brake shoes into engagement with a drum to effect a brake application. The lever has a first end connected to the brake shoes and a second end with a tine fixed thereto to which a cable is connected to apply an input force to effect a brake application. A predetermined force is applied to the tine to deflect the tine and a tab engages the lever to hold the tine in the deflected position. The tine and second end of the lever move in unison in response to an input force until the input force exceeds the predetermined force such that while the tine and cable continue to move in unison the deflection of the tine proportionally reduces the movement of the first end of the lever and as a result an actuation force applied to effect a brake application is correspondingly reduced.

Abstract: A drum brake has cylinders symmetrically fixed to a stationary member. Each cylinder has an axial bore therein with a groove for retention of a seal. A piston engages each seal to define chambers that receive pressurized fluid. Webs for friction members have a first end pined to an opposite cylinder and a second end connected to an opposite piston and to each other by a strut. Pressurized fluid acts on the pistons to move the second ends with respect to the first ends and simultaneously bring the friction members into engagement with a drum to effect a brake application. The seals acts on and return the pistons to a rest position in an absence of pressurized fluid. A pawl on a lever is moved into engagement with the strut to bring the first and second friction members into engagement with the drum to manually effect a brake application.

Abstract: A disc brake has a support with a first end separated from a second end by first and second side walls that retain actuation members to move the first and second friction members into engagement with a rotor and effect a brake application. First and second perpendicular projections that extend from the support are aligned with the first wall and third and fourth perpendicular projections that extend from the support and are aligned with the second wall. The first and second friction members have first and second radial projections located between a first end and a second end. Beams connect the radial projections with the perpendicular projections to align the first and second friction members with the rotor and pivot on the perpendicular projections to carry reaction forces created during a brake application into the first end of the support.

Abstract: An ink or paint formulation, but in particular an ink formulation, which comprises a hyperbranched polyesteramide is described and claimed. In particular, the formulation will comprise (i) a colorant, (ii) a hyperbranched polyesteramide and (iii) a solvent. The hyperbranched polyesteramide used is suitably chemically “matched” to a coating in the substrate to which the formulation is to be applied, so that they bond together strongly, and combinations of formulations and substrates are also claimed.

Abstract: The present invention provides compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thrombotic disorders. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula I, processes for preparing compounds of Formula I, and intermediates useful for preparing compounds of Formula I.

Abstract: The present invention comprises an oil system for supplying and controlling oil flow in an internal combustion engine having a variable camshaft timing (VCT) device, comprising a pressurized oil supply providing lubricating oil to the engine and the variable cam timing device and an oil circuit connecting the oil pump with the VCT and a main oil gallery of the engine via a valve apparatus. The valve apparatus responds to oil pressure near the outlet of the oil pump so that oil flows to the main oil gallery when oil pressure is above a predetermined pressure. When the VCT requests oil flow, oil pressure in the system drops. If the pressure drops below the predetermined pressure, the valve apparatus causes a reduction in flow to the main gallery.

Abstract: A disc brake has an anchor that is fixed to a housing to align first and second rails and friction pads for each of first and second friction members with radial surfaces on a rotor. The friction pads are moved into engagement with radial surfaces by an actuation force to develop a brake force and reaction forces that are carried into the anchor to oppose the rotation of the rotor during a brake application. The anchor has projections on the first rail located in planes that are offset from radial engagement surfaces on the rotor. The friction members each have a carrier with an outwardly projecting lip on a first end through which the brake forces are transmitted into the projections. Since the projections are offset a moment is created by the reactions forces and an axial component derived thereof added to the actuation force during a brake application.

Abstract: A control valve for a brake booster having a first member with a first bore, a second member located in the first bore and having a second bore, a plunger located in the second bore and connected to an input member. A gear fixed to the second member with teeth that engage a first rack retained in the first body and a stationary rack within the brake booster. A force applied to the input member controls the development of a pressure differential that moves a wall during a brake application. Movement of the wall causes a rotative torque to be transmitted from the first rack into teeth such that the gear moves with respect to the second rack and the second body to separates from the first body and as a result the travel of input member is less than the travel of the wall during a brake application.

Abstract: A master cylinder wherein an input force applied to a bearing assembly pushes and rotates an input piston into a bore of a housing through the engagement between a helical groove on its outer surface and a pin on the housing to act on a primary piston in the bore that supplies pressurized fluid to wheel brakes. A threaded connection that connects the input piston to a primary master cylinder piston has an opposite direction thread from that of the helical groove in the input piston and as a result the input piston moves at a different rate of travel within the bore than the primary piston such that initial movement of the input piston is accentuated in the movement of primary piston and after a predetermined travel of the input piston into the bore, the input piston and primary piston travel in unison to effect a brake application.

Abstract: A support for a disc brake has first and second bores in a first projection and third and fourth bores in a second projection located in a same horizontal plane and the first and third bores aligned in a first vertical plane and the second and fourth bores aligned in a second vertical plane. A first pin retained in the first and third bores extend through a first lever to position a first friction member adjacent a rotor while a second pin extends through the second and fourth bores to position a second friction member adjacent the rotor. Pressurized fluid is supplied to act on a piston retained in the first lever such that the first lever pivots on the first pin and the second lever pivots on the second pin to thereafter move the first and second friction members into engagement with the rotor and effect a brake application.

Abstract: A brake actuating assembly includes a cam member that has first and second cam surfaces. A first piston in a first hydraulic circuit is selectively enabled to axially translate the cam member from a released position to an actuation position while an actuation piston moves friction surfaces into engagement with a rotor to effect a brake application. During a brake application, pressurized fluid is diverted away from a second piston in a second hydraulic circuit that is later enabled to return the cam member to the released position. A resilient assembly selectively engages the second cam surface to obliquely move the cam member toward the actuation piston during a brake application. An electrically actuable valve supplies pressure fluid that acts on and moves the resilient assembly away from the second cam surface and thereafter allow a second hydraulic piston to return cam member to the released position.

Abstract: This invention discloses quinoxalinones which display inhibitory effects on serine proteases such as factor Xa, thrombin, and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable compositions comprising the compounds, their salts or prodrugs, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.

Abstract: An adhesive composition which can be formulated to have low or substantially no VOC emissions is provided. Adhesives in accordance with the invention can be formulated as high solids, one-part, reactive, cross-linked adhesives. This can be achieved by utilizing amide-ester-acrylate reactions or reactions with any other carboxylated polymers. Adhesive compositions in accordance with the invention can include oils, such as various drying oils and similarly acting polymers, co-polymers, and fatty acids. Adhesives in accordance with the invention can also include various hydrocarbon resins, particularly crosslinkable hydrocarbons having a melting point in the range 70° C. to 140° C. Cross-linking agents, such as materials with pendant oxazoline groups are also advantageously included. Various other mixing, flow and other handling ingredients can also be included.

Abstract: The invention discloses quinolinones which display inhibitory effects on serine proteases such as factor Xa, thrombin and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable compositions comprising the compounds, their salts or prodrugs, and methods of using them a therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.