Patents by Inventor John Edward Hodgson

John Edward Hodgson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel tRNA Synthetase
    Publication number: 20080124313
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Application
    Filed: December 10, 2007
    Publication date: May 29, 2008
    Applicant: REPLIDYNE, INC.
    Inventors: JOHN EDWARD HODGSON, ELIZABETH JANE LAWLOR
  • tRNA synthetase
    Patent number: 7335499
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: February 26, 2008
    Assignee: Replidyne, Inc.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Purified polypeptides from
    Patent number: 7250285
    Abstract: The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: July 31, 2007
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Robert King Stodola, Martin Karl Russel Burnham
  • Compounds
    Patent number: 7176299
    Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: February 13, 2007
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M. Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M. Ward, Richard Lloyd Warren
  • Methionyl tRNA synthetase polypeptides from Staphylococcus aureus
    Patent number: 6989255
    Abstract: The invention provides methionyl tRNA synthetase (tRS) enzymes from Staphylococcus aureus and methods of producing such tRS by recombinant techniques. Also provided are methods for utilizing tRS for the protection against infection, particularly bacterial infection, most particularly Staphylococcus aureus infection.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: January 24, 2006
    Assignee: Replidyne, Inc.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Host cells comprising Streptomyces clavuligerus chromosomal DNA fragments encoding enzymes for ?-lactam antibiotic biosynthesis
    Patent number: 6964865
    Abstract: DNA sequences obtained from S. clavuligerus ATCC 27064, recombinant vectors incorporating such sequences and hosts transformed with such vectors are disclosed. The DNA comprises one or more genes coding for one or more enzymes involved in the biosynthesis of penicillin and cephalosporin ?-lactams and such enzymes are expressed by hosts into which the recombinant vectors are transformed. The DNA and the enzymes encoded thereby have utility in the preparation of penicillins and cephalosporins, both known and novel, possessing pharmacological, especially antimicrobial, activity.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: November 15, 2005
    Assignee: Beecham Group plc
    Inventors: Martin Karl Russel Burnham, Ian David Normansell, John Edward Hodgson
  • Polynucleotides encoding methionyl tRNA synthetase from Staphylococcus aureus, related products and methods
    Patent number: 6903204
    Abstract: The invention provides Staphylococcus aureus methionyl tRNA synthetase polypeptides and DNA (RNA) encoding Staphylococcus aureus methionyl tRNA synthetase polypeptides and methods for producing such poypeptides by recombinant techniques. Also provided are methods for utilizing Staphylococcus aureus methionyl tRNA synthetase polypeptides for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: June 7, 2005
    Assignee: Replidyne, Inc.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • ribG
    Publication number: 20040265872
    Abstract: The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: April 14, 2004
    Publication date: December 30, 2004
    Applicant: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M. Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M. Ward, Richard Lloyd Warren
  • Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression
    Patent number: 6709859
    Abstract: DNA sequences obtained from S. clavuligerus ATCC 27064, recombinant vectors incorporating such sequences and hosts transformed with such vectors are disclosed. The DNA comprises one or more genes coding for one or more enzymes involved in the biosynthesis of penicillin and cephalosporin &bgr;-lactams and such enzymes are expressed by hosts into which the recombinant vectors are transformed. The DNA and the enzymes encoded thereby have utility in the preparation of penicillins and cephalosporins, both known and novel, possessing pharmacological, especially antimicrobial, activity.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: March 23, 2004
    Assignee: Beecham Group p.l.c.
    Inventors: Martin Karl Rossel Burnham, Ian David Normansell, John Edward Hodgson
  • Novel compounds
    Publication number: 20040014037
    Abstract: The invention provides RF-1 polypeptides and DNA (RNA) encoding RF-1 polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing RF-1 polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: September 14, 2001
    Publication date: January 22, 2004
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Richard O. Nicholas, Robert King Stodola
  • Novel compounds
    Publication number: 20040002133
    Abstract: DNA sequences obtained from S. clavuligerus ATCC 27064, recombinant vectors incorporating such sequences and hosts transformed with such vectors are disclosed.
    Type: Application
    Filed: March 31, 2003
    Publication date: January 1, 2004
    Applicant: Beecham Group plc
    Inventors: Martin Karl Russel Burnham, Ian David Normansell, John Edward Hodgson
  • Novel compounds
    Publication number: 20030180834
    Abstract: DNA sequences obtained from S. clavuligerus ATCC 27064, recombinant vectors incorporating such sequences and hosts transformed with such vectors are disclosed.
    Type: Application
    Filed: March 21, 2003
    Publication date: September 25, 2003
    Applicant: Beecham Group plc
    Inventors: Martin Karl Russel Burnham, Ian David Normansell, John Edward Hodgson
  • FtsH from Staphylococcus aureus
    Patent number: 6573066
    Abstract: The invention provides ftsH polypeptides, polynucleotides encoding ftsH polypeptides and related polynucleotides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic methods for detecting Staphylococcus aureus.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: June 3, 2003
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: John Edward Hodgson, Owen Jenkins, Gillian Sarginson
  • Novel tig
    Publication number: 20020150956
    Abstract: The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: April 6, 2001
    Publication date: October 17, 2002
    Inventors: Martin Karl Russel Burnham, Andrew Fosberry, John Edward Hodgson, Deborah Dee Jaworski, Elizabeth J. Lawlor, Martin Rosenberg, Christopher Michael Traini, Min Wang, Judith Ward, Richard Warren
  • Compounds
    Patent number: 6465621
    Abstract: The invention provides ERA polypeptides and DNA (RNA) encoding ERA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ERA polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: October 15, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward
  • Fibronectin binding proteins
    Patent number: 6461614
    Abstract: The invention provides Fibronectin Binding Protein polypeptides and DNA (RNA) encoding Fibronectin Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Fibronectin Binding Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: October 8, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC
    Inventors: John Edward Hodgson, Martin Karl Russel Burnham
  • Member of ATP dependent protease family, clpL
    Patent number: 6447773
    Abstract: The invention provides clpL polypeptides and DNA (RNA) encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: September 10, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Andrew Fosberry, Elizabeth J Lawlor
  • ribB
    Patent number: 6448036
    Abstract: The invention provides ribB polypeptides and polynucleotides encoding ribB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: September 10, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M Ward, Richard Lloyd Warren
  • Novel ribB
    Publication number: 20020091236
    Abstract: The invention provides ribB polypeptides and polynucleotides encoding ribB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribB polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 18, 2001
    Publication date: July 11, 2002
    Inventors: Michael Terence Black, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Anna Lisa Kosmatka, Richard Oakley Nicholas, Leslie Marie Palmer, Lisa Kathleen Shilling, Robert King Stodola, Richard Lloyd Warren
  • Novel era
    Publication number: 20020086385
    Abstract: The invention provides era polypeptides and DNA (RNA) encoding era polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing era polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: March 29, 2001
    Publication date: July 4, 2002
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Robert Reid, Martin Rosenberg, Phillip Zarfos