Patents by Inventor John Edward Hodgson

John Edward Hodgson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SpoIIIe polynucleotides
    Patent number: 5891667
    Abstract: The invention provides spoIIIE polypeptides and DNA (RNA) encoding spIIIE polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing spoIIIE polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: April 6, 1999
    Assignee: SmithKline Beecham, p.l.c.
    Inventors: John Edward Hodgson, Alison Frances Chalker
  • Polynucleotides encoding GTP cyclohydrolase II (ribA)
    Patent number: 5891672
    Abstract: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: April 6, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Min Wang, Judith M Ward, Richard Lloyd Warren, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, David Justin Charles Knowles, Michael Arthur Lonetto, Jeffrey Mooney, Michael Terence Black, Martin Karl Russell Burnham, Christine Debouck, Jason Craig Fedon, John Edward Hodgson, Deborah Dee Jaworski, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Yi Yi Zhong
  • gbpA
    Patent number: 5885805
    Abstract: The invention provides gbpA polypeptides and DNA (RNA) encoding gbpA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gbpA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: March 23, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Arthur Lonetto, Patrick Vernon Warren, Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward
  • Ferrichrome transport ATP-binding protein
    Patent number: 5882891
    Abstract: The invention provides Ferrichrome transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Ferrichrome transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Ferrichrome transport ATP-Binding Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: March 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakly Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • yitJ
    Patent number: 5882897
    Abstract: The invention provides yitJ polypeptides and DNA (RNA) encoding yitJ polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yitJ polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: March 16, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham, p.l.c.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • PCR A
    Patent number: 5858718
    Abstract: The invention provides pcrA polypeptides and DNA (RNA) encoding pcrA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pcrA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Robert King Stodola, David J. Holmes
  • Fibronectin binding protein B compounds
    Patent number: 5858709
    Abstract: Novel fibronectin binding protein B polypeptides and DNA (RNA) encoding such novel fibronectin binding protein B and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such novel fibronectin binding protein B for the treatment of infection, particularly bacterial infections. Antagonists against such novel fibronectin binding protein B and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of novel fibronectin binding protein B nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding novel fibronectin binding protein B family and for detecting the polypeptide in a host.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Martin Karl Russell Burnham
  • TCSTS polynucleotides
    Patent number: 5854020
    Abstract: Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such the polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: December 29, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Nicola Gail Wallis
  • Two component signal transduction system response regulator polynucleotides of Staphylococcus aureus
    Patent number: 5846772
    Abstract: Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such the polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: December 8, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Nicola Gail Wallis
  • Glucose kinase from streptococcus pneumoniae
    Patent number: 5840560
    Abstract: The invention provides Glucose Kinase polypeptides and DNA (RNA) encoding Glucose Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Glucose Kinase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: November 24, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O. Nicholas, Robert King Stodola, Martin Karl Russel Burnham
  • Polynucleotide encoding saliva binding protein
    Patent number: 5801234
    Abstract: Saliva binding protein polypeptides and DNA (RNA) of Staphylococcus aureus encoding such saliva binding protein and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such saliva binding protein for the treatment of infection, particularly bacterial infections. Antagonists against such saliva binding protein and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of saliva binding protein nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding saliva binding protein family and for detecting the polypeptide in host.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: September 1, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Martin Karl Russell Burnham
  • DNA encoding threonyl tRNA synthetase from staphylococcus aureus
    Patent number: 5795757
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: August 18, 1998
    Assignee: SmithKline Beecham, p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoding asparaginyl tRNA synthetase from staphylococcus aureus
    Patent number: 5789217
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: August 4, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoding valyl tRNA synthetase from Staphylococcus aureus
    Patent number: 5789218
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: August 4, 1998
    Assignee: Smithkline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoding cysteinyl tRNA synthetase from Staphylococcus aureus
    Patent number: 5776749
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: July 7, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Alanyl tRNA synthetase polynucleoyides of staphlococcus
    Patent number: 5776750
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: July 7, 1998
    Assignee: Smithkline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoding arginyl tRNA synthetase from staphylococcus aureus
    Patent number: 5763246
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: June 9, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA molecules and vectors regarding clavulanic acid biosynthesis enzymes
    Patent number: 5759831
    Abstract: DNA sequences obtained from S. clavuligerus, recombinant vectors incorporating such sequences and hosts transformed with such vectors are disclosed. The DNA comprises one or more genes encoding one or more enzymes involved in the biosynthesis of clavulanic acid and may be used to improve the yield of clavulanic acid produced by clavulanic acid-producing organisms such as S. clavuligerus ATCC 27064.
    Type: Grant
    Filed: December 1, 1993
    Date of Patent: June 2, 1998
    Assignee: Beecham Group p.l.c.
    Inventors: John Edward Hodgson, Alison Jane Earl
  • DNA encoding phenylalanyl tRNA synthetase from Staphylococcus aureus
    Patent number: 5756329
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: May 26, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • DNA encoing leucyl TRNA synthetase from staphylococcus aureus
    Patent number: 5750387
    Abstract: The invention provides novel tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: May 12, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor