Patents by Inventor John Edwin Munroe

John Edwin Munroe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NRF2 PROTEIN DEGRADERS
    Publication number: 20260055097
    Abstract: The present disclosure provides compounds represented by Formula A-I: and the salts or solvates thereof, wherein R1, R2a, R2b, R2c, R3, R4a, R4b, R4c, R4d, L, X, Y, and B1 are as defined in the specification. Compounds having Formula A-I are nuclear factor erythroid 2-related factor 2 (Nrf2) degraders useful for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 23, 2024
    Publication date: February 26, 2026
    Inventors: John Edwin MUNROE, Robert Christian Wild
  • NRF2 PROTEIN DEGRADERS
    Publication number: 20250145611
    Abstract: The present disclosure provides compounds represented by Formula A-I: and the salts or solvates thereof, wherein R1, R2a, R2b, R2c, R3, R4a, R4b, R4c, R4d, L, X, Y, and B1 are as defined in the specification. Compounds having Formula A-I are nuclear factor erythroid 2-related factor 2 (Nrf2) degraders useful for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 23, 2024
    Publication date: May 8, 2025
    Inventors: John Edwin MUNROE, Robert Christian Wild
  • Inhibition of viral replication
    Patent number: 6037348
    Abstract: The present invention provides a method of inhibiting influenza and flaviviral replication based on a mechanism of action in which HA-mediated fusion or E protein mediated fusion is inhibited by a fusion inhibiting agent which binds, complexes or otherwise becomes associated with HA or E protein during the translation of the target protein and/or its vesicular transport.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: March 14, 2000
    Assignee: Eli Lilly and Company
    Inventors: Joseph Matthew Colacino, Steven Duane Hatch, William Joseph Hornback, Mark Ayer Muesing, John Edwin Munroe, Kirk Alan Staschke, Joseph Chiou-Chung Tang