Patents by Inventor John Emmerson CAMPBELL

John Emmerson CAMPBELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED BENZENE COMPOUNDS
    Publication number: 20210060027
    Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: July 9, 2020
    Publication date: March 4, 2021
    Inventors: Kevin Wayne Kuntz, John Emmerson Campbell, Masashi Seki, Syuji Shirotori, Wataru Itano, Wanjun Zheng
  • Multicyclic compounds and methods of use thereof
    Patent number: 10894033
    Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: January 19, 2021
    Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Liming Shao, John Emmerson Campbell, Michael Charles Hewitt, Una Campbell, Taleen G. Hanania
  • SUBSTITUTED BENZENE AND 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS
    Publication number: 20200361914
    Abstract: The present invention relates to substituted benzene compounds and bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: March 24, 2020
    Publication date: November 19, 2020
    Inventor: John Emmerson CAMPBELL
  • MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20200323819
    Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
    Type: Application
    Filed: February 14, 2020
    Publication date: October 15, 2020
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Liming SHAO, John Emmerson CAMPBELL, Michael Charles HEWITT, Una CAMPBELL, Taleen G. HANANIA
  • AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND DERIVATIVES THEREOF
    Publication number: 20200317642
    Abstract: The present disclosure relates to amine-substituted heterocyclic compounds and derivatives thereof. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) by administering an amine-substituted heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: October 17, 2018
    Publication date: October 8, 2020
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN, James Edward John MILLS, Michael John MUNCHHOF
  • HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20200277286
    Abstract: Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
    Type: Application
    Filed: December 20, 2019
    Publication date: September 3, 2020
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: John Emmerson CAMPBELL, Una CAMPBELL, Taleen G. HANANIA, Liming SHAO
  • AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS, SALTS THEREOF, AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20200247790
    Abstract: The present disclosure relates to amine-substituted heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) by administering an amine-substituted heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: October 18, 2018
    Publication date: August 6, 2020
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN, James Edward John MILLS, Michael John MUNCHHOF
  • METHODS OF USING EHMT2 INHIBITORS
    Publication number: 20200113901
    Abstract: The present disclosure relates to a method of preventing or treating an imprinting disorder via administering an EHMT2 inhibitor compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: March 30, 2018
    Publication date: April 16, 2020
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN, Elayne PENEBRE, Kat COSMOPOULOS, Christine KLAUS
  • Substituted cyclopropanes as PDE-10 inhibitors
    Patent number: 10604536
    Abstract: Provided herein are substituted cyclopropane compounds, and pharmaceutical compositions thereof, useful for the treatment of, for example, central nervous system and metabolic diseases and disorders.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: March 31, 2020
    Assignee: Sunovion Pharamaceuticals Inc.
    Inventors: John Emmerson Campbell, Philip G. Jones, Scott Malcolm
  • Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors
    Patent number: 10570156
    Abstract: Provided herein are cyclic nucleotide phosphodiesterase inhibitors of Formula (I) of claim 1, and pharmaceutical compositions thereof, useful for the treatment of, for example, central nervous system and metabolic diseases and disorder.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: February 25, 2020
    Assignee: SUNOVION PHARMACEUTICALS INC.
    Inventors: John Emmerson Campbell, Philip Wendell Jones, Michael Charles Hewitt
  • COMBINATION THERAPIES WITH EHMT2 INHIBITORS
    Publication number: 20200054635
    Abstract: The present disclosure relates to a method of preventing or treating a cancer via administering an EHMT2 inhibitor or a combination comprising an EHMT2 inhibitor compound and one or more additional therapeutic agent disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds or combinations for research or other non-therapeutic purposes.
    Type: Application
    Filed: April 20, 2018
    Publication date: February 20, 2020
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN, Maria Alejandra RAIMONDI, Christine KLAUS, Elayne PENEBRE
  • Substituted quinoxalines as PDE-10 inhibitors
    Patent number: 10562916
    Abstract: Provided herein are cyclic nucleotide phosphodiesterase inhibitors, and pharmaceutical compositions thereof, useful for the treatment of, for example, central nervous system and metabolic diseases and disorder.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: February 18, 2020
    Assignee: Sunovion Pharmaceuticals, Inc.
    Inventors: John Emmerson Campbell, Michael Charles Hewitt, Philip Xinhe Jones, Linghong Xie
  • Heteroaryl compounds and methods of use thereof
    Patent number: 10556890
    Abstract: Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: February 11, 2020
    Assignees: Sunovion Pharmaceuticals Inc., PGI DRUG DISCOVERY LLC
    Inventors: John Emmerson Campbell, Una Campbell, Taleen G. Hanania, Liming Shao
  • AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20200039998
    Abstract: The present disclosure relates to amine-substituted heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering an amine-substituted heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: December 19, 2017
    Publication date: February 6, 2020
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN
  • SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS
    Publication number: 20200039961
    Abstract: The present disclosure relates to substituted fused bi- or tri-heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell anemia) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering a substituted fused bi- or tri-heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 6, 2020
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN
  • MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20190125722
    Abstract: Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
    Type: Application
    Filed: August 30, 2018
    Publication date: May 2, 2019
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Liming SHAO, John Emmerson CAMPBELL, Michael Charles HEWITT, Una CAMPBELL, Taleen G. HANANIA
  • SUBSTITUTED BENZENE COMPOUNDS
    Publication number: 20190060322
    Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: September 4, 2018
    Publication date: February 28, 2019
    Inventors: Kevin Wayne KUNTZ, John Emmerson CAMPBELL, Masashi SEKI, Syuji SHIROTORI, Wataru ITANO, Wanjun ZHENG
  • Heteroaryl compounds and methods of use thereof
    Patent number: 10189825
    Abstract: Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: January 29, 2019
    Assignees: SUNOVION PHARMACEUTICALS INC., PGI DRUG DISCOVERY LLC
    Inventors: John Emmerson Campbell, Una Campbell, Taleen G. Hanania, Liming Shao
  • Substituted 6,5-fused bicyclic heteroaryl compounds
    Patent number: 10174019
    Abstract: The present invention relates to azole bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: January 8, 2019
    Assignee: Epizyme, Inc.
    Inventors: John Emmerson Campbell, Kevin Wayne Kuntz
  • Substituted benzene compounds
    Patent number: 10150764
    Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: December 11, 2018
    Assignee: Epizyme, Inc.
    Inventor: John Emmerson Campbell