Abstract: A system for patient imaging is provided. The system includes an imaging system and a parameter generator to determine parameters of at least a first phase of an injection procedure. The imaging system includes a scanner that has at least one x-ray tube. The parameter generator is programmed to determine at least one of the parameters on the basis of a voltage to be applied to the at least one x-ray tube during an imaging procedure. A method of controlling an injector system is also provided, and the method includes determining injection parameters, at least one of which is determined on the basis of a voltage to be applied to an x-ray tube during the imaging procedure, as well as controlling the injector system at least in part on the basis of the determined injection parameters.

Abstract: A system has a parameter generation system that includes a processor, an input system and a memory system in which an algorithm is stored. Upon execution by the processor, the algorithm is used to determine parameters of at least one phase of an injection procedure to be performed on a patient based at least in part upon the type of injection procedure selected via the input system. The volume of a pharmaceutical to be delivered to the patient during the injection procedure is determined at least in part on the basis of the concentration of a contrast enhancing agent contained in the pharmaceutical and at least in part on the basis of a function that depends upon and varies with a parameter of the patient such as the weight, the body mass index, the body surface area or the cardiac output of the patient.

Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.

Abstract: A system for enabling delivery of fluid in an injection procedure to be performed on a patient in connection with a diagnostic imaging procedure is disclosed. The system includes a controller operably associated with at least one pressurizing mechanism though which at least one of a first and a second fluid contained within at least one fluid container is injectable into the patient. The first fluid includes a contrast enhancing agent while the second fluid does not. The controller includes a programming system for programming an injection protocol having a plurality of phases to effect enhancement of at least one region of interest of the patient over a scan duration of the diagnostic imaging procedure. The programming system includes an algorithm that enables computation of a ratio of the first and second fluids based on at least a peak enhancement that occurs in at least one region of interest.

Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.

Abstract: A system for patient imaging is provided. The system includes an imaging system and a parameter generator to determine parameters of at least a first phase of an injection procedure. The imaging system includes a scanner that has at least one x-ray tube. The parameter generator is programmed to determine at least one of the parameters on the basis of a voltage to be applied to the at least one x-ray tube during an imaging procedure. A method of controlling an injector system is also provided, and the method includes determining injection parameters, at least one of which is determined on the basis of a voltage to be applied to an x-ray tube during the imaging procedure, as well as controlling the injector system at least in part on the basis of the determined injection parameters.

Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

Abstract: A system includes a parameter generation system to determine at least one parameter for an injection procedure (for example, a parameter of an injection protocol or an imaging system parameter), the parameter generator system includes a physiologically based pharmacokinetic model to model propagation of a contrast medium injected into a patient including at least one of a non-linear saturation term in a peripheral venous compartment, at least one configurable transport delay term through at least one compartment, or an adaptation to model volumetric flow rate of blood and an effect thereof on the propagation of contrast medium after injection of contrast medium ceases. The physiologically based pharmacokinetic model can, for example, be discretizable.

Abstract: A system for patient imaging is provided. The system includes an imaging system and a parameter generator to determine parameters of at least a first phase of an injection procedure. The imaging system includes a scanner that has at least one x-ray tube. The parameter generator is programmed to determine at least one of the parameters on the basis of a voltage to be applied to the at least one x-ray tube during an imaging procedure. A method of controlling an injector system is also provided, and the method includes determining injection parameters, at least one of which is determined on the basis of a voltage to be applied to an x-ray tube during the imaging procedure, as well as controlling the injector system at least in part on the basis of the determined injection parameters.

Abstract: A system and method of managing workflow for a variety of injection procedures preferably includes a display that provides a graphical representation of the steps required to initiate an injection procedure. The system can, for example, set forth a suggested order or sequence for the steps to be completed, and display the suggested sequence of steps graphically. Various steps may optionally require completion of ancillary operations as a requirement for completion of the selected step.

Abstract: Systems and methods for delivering a medical fluid are disclosed. The system includes a fluid flow path, a fluid administration device adapted to deliver the medical fluid through the fluid flow path, and a controller in communication with the fluid administration device. The method includes using the system to determine a desired flow rate of the medical fluid at a distal end of the fluid flow path based upon at least a desired flow profile of the medical fluid at the distal end. The method further includes initiating a fluid delivery operation by delivering the medical fluid through the fluid flow path according to fluid delivery parameters provided to the fluid administration device by the controller. Information about the fluid delivery operation may be received at the controller which executes a control function to adjust the fluid delivery parameters based on the received information.

Abstract: A method and system for tailoring an injection protocol to an individual patient, wherein the injection protocol is administered in connection with a diagnostic imaging procedure. The method includes: administering a test injection of a fluid including a contrast enhancing fluid into the patient at an administration site; performing a test scan of one or more regions of interest of the patient as the fluid propagates through the patient to obtain scan data; determining from the scan data an enhancement output from each of the one or more regions of interest at a plurality of points in time as a result of the propagation of the fluid through the patient; and determining the injection protocol for the patient based at least in part upon the enhancement output from each of the one or more regions of interest at each of the plurality of points in time.

Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

Abstract: A system includes a parameter generation system to determine parameters of at least one phase of an injection procedure based at least in part upon a type of the injection procedure. The parameter generator system determines the amount of a pharmaceutical that is to be delivered to a patient at least in part on the basis of the concentration of an agent in the pharmaceutical and at least on part on the basis of a function that depends upon and varies with a patient parameter. The patient parameter can, for example, be weight, body mass index, body surface area or cardiac output. The pharmaceutical can, for example, include a contrast enhancing agent for use in an imaging procedure.

Abstract: A method for injection of an imaging contrast into a patient, includes: a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time; and b. in a second phase, injecting a fluid having a second concentration of contrast agent for a second period of time. The osmolarity of the second phase is higher than the osmolarity of the first phase. In several embodiments in which the contrast agent of the first phase is of the same composition as the contrast agent of the second phase, the second concentration can be higher than the first concentration. The first phase can, for example, precede the second phase. The method can further include: c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time. The osmolarity of the third phase is lower than the osmolarity of the second phase.

Abstract: A system which includes a pressurizing mechanism to pressurize a fluid including a contrast enhancement agent for delivery to a patient and a control system in operative connection with the pressurizing mechanism. The control system includes a system to adjust control of fluid injection based upon a measurement of renal function of the patient.

Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.

Abstract: A method for injection of an imaging contrast into a patient, includes: a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time; and b. in a second phase, injecting a fluid having a second concentration of contrast agent for a second period of time. The osmolarity of the second phase is higher than the osmolarity of the first phase. The method can further include: c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time. The osmolarity of the third phase is lower than the osmolarity of the second phase. In embodiments in which the composition of the contrast agent of the third phase is the same as the composition of the contrast agent of the second phase, the third concentration can be lower than the second concentration.

Abstract: A fluid delivery system includes a fluid container, two or more pressurizing chambers in fluid connection with the fluid container, a drive mechanism in operative connection with the two or more pressurizing chambers to pump fluid from the fluid container and an outlet in fluid connection with the two or more pressurizing chambers. Each of the two or more pressurizing chambers is formed from a flexible, resilient material that is adapted to be compressed to pressurize fluid therewithin.

Abstract: A system and method for mixing and delivering fluids such as contrast media and saline is disclosed including at least two fluid sources, a pump, a joining fluid path for connecting the at least two fluid sources to an inlet to of the pump, and a valve device in the fluid path upstream of the pump. The valve device includes an actuator adapted to restrict flow in at least one of the respective fluid lines connecting the at least two fluid sources to the pump inlet. A patient interface device may be associated with an outlet of the pump. The valve device actuator is generally adapted to restrict the flow in at least one of the respective fluid lines such that a positional change in valve device actuator position provides a change in fluid mixture ratio of the fluids from the at least two fluid sources to the pump inlet.