Patents by Inventor John F. Lang

John F. Lang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF 2-DEOXY-2-FLUORO-2-METHYL-D-RIBOFURANOSYL NUCLEOSIDE COMPOUNDS
    Publication number: 20130324709
    Abstract: An improved process for the preparation of (2?R)-2?-deoxy-2?-fluoro-2?-methylcytidine derivatives of formula I wherein R1 is selected from C1-4-alkyl is described. The (2?R)-2?-deoxy-2?-fluoro-2?-methylcytidine derivatives of formula I have the potential to be useful as prodrugs for potent inhibitors of the Hepatitis C Virus (HCV) NS5B polymerase.
    Type: Application
    Filed: May 28, 2013
    Publication date: December 5, 2013
    Inventors: Robert Carr, Stefan Hildbrand, Mark L. Hodges, Michael Kammerer, John F. Lang, William J. Lawrimore, III, Dieu Nguyen
  • Synthesis of bromobiphenyls
    Patent number: 5254776
    Abstract: Bromobiphenyls (such as 2-fluoro-4-bromobiphenyl) are synthesized by reacting together a phenylboronic acid (such as phenylboronic acid) and a bromoiodobenzene (such as 2-fluoro-4-bromoiodobenzene). The reaction generally takes place with the aid of a catalyst (such as palladium in a zero valance state) and an inert solvent (such as fluorobenzene). Control of temperature is very important to obtain both an acceptable reaction rate and an acceptable level of terphenyl byproduct.
    Type: Grant
    Filed: July 17, 1992
    Date of Patent: October 19, 1993
    Assignee: Mallinckrodt Specialty Chemicals Company
    Inventors: John F. Lang, Narayanasamy Gurusamy
  • Synthesis of fluorobenzaldehydes
    Patent number: 5138099
    Abstract: 4-fluorobenzaldehydes are formed from compounds of the formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different, and represent H, halogen, or an alkyl group of from 1 to about 10 carbon atoms, wherein, when at least one of R.sub.1, R.sub.2, R.sub.3 or R.sub.4 is halogen, at least one of remaining R.sub.1, R.sub.2, R.sub.3 or R.sub.4 is alkyl. the compound of formula of (I) is reacted with a formylating agent in the presence of FeCl.sub.3 in a reaction mixture, from which is separated a compound of the formula (II) ##STR2## wherein R.sub.1, R.sub.2 , R.sub.3 and R.sub.4 are as defined above.
    Type: Grant
    Filed: July 31, 1991
    Date of Patent: August 11, 1992
    Assignee: Mallinckrodt Specialty Chemicals Company
    Inventor: John F. Lang
  • Method and apparatus for permanent marking of metal
    Patent number: 4090599
    Abstract: A method and apparatus are disclosed for permanently marking a metal workpiece. The apparatus comprises a support for supporting the apparatus in contact with the workpiece. A stamp holding means adapted to receive a predetermined number of stamps engages the support and carries the stamps.The method comprises the steps of engaging the stamp holder with the support. Placing the support on the workpiece. Striking the stamps until the characters are at the desired depth and then removing the stamp holder from the workpiece.
    Type: Grant
    Filed: September 22, 1975
    Date of Patent: May 23, 1978
    Inventors: Calvin E. Kelly, John F. Lang
  • System for making cutouts and angular cuts in stepped siding
    Patent number: 3986418
    Abstract: A system for making cutouts and angular cuts in stepped siding uses a punch to remove, at the desired cut location, a rectangular section including the step and a small portion of both faces adjacent the step. The punch operates in a shearing manner with cutting surfaces progressively contacting the siding as the punch is moved into the die. Final cuts of the siding are made with cutters which do not require support of the stepped portion of the siding.
    Type: Grant
    Filed: March 12, 1975
    Date of Patent: October 19, 1976
    Assignee: United States Steel Corporation
    Inventors: John F. Lang, Robert A. Wilshire, Jr.