Patents by Inventor John F. Mehlmann

John F. Mehlmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11377440
    Abstract: Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: July 5, 2022
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: David T. Fosbenner, Todd L. Graybill, Jianxing Kang, Bryan W. King, Yunfeng Lan, Lara Kathryn Leister, Mukesh K. Mahajan, John F. Mehlmann, Angel I. Morales-Ramos, George Scott Pesiridis, Joshi M. Ramanjulu, Joseph J. Romano, Stuart Paul Romeril, Mark J. Schulz, Huiqiang Zhou, Junya Qu
  • Publication number: 20210238172
    Abstract: The invention relates to combinations comprising a compound of the formula: or a salt thereof; and one or more additional pharmaceutically agents active against HIV, and methods of using the same.
    Type: Application
    Filed: October 4, 2018
    Publication date: August 5, 2021
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Adam Kenneth CHARNLEY, Michael Gerard DARCY, Jason W. DODSON, Xiaoyang DONG, David FAVRE, Terry Vincent HUGHES, Jianxing KANG, Lara Kathryn LEISTER, Yuehu LI, Yiqian LIAN, John F. MEHLMANN, Neysa NEVINS, Joshi M. RAMANJULU, Joseph J. ROMANO, Gren Z. WANG, Guosen YE, Daohua ZHANG
  • Publication number: 20200291001
    Abstract: Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Application
    Filed: October 4, 2018
    Publication date: September 17, 2020
    Inventors: David T. FOSBENNER, Todd L. GRAYBILL, Jianxing KANG, Bryan W. KING, Yunfeng LAN, Lara Kathryn LEISTER, Mukesh K. MAHAJAN, John F. MEHLMANN, Angel I. MORALES-RAMOS, George Scott PESIRIDIS, Joshi M. RAMANJULU, Joseph J. ROMANO, Stuart Paul ROMERIL, Mark J. SCHULZ, Huiqiang ZHOU, Junya QU
  • Patent number: 10220030
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: March 5, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Pamela A. Haile, Robert W. Marquis, Jr., John F. Mehlmann, Joseph J. Romano, Robert R. Singhaus, Jr., Gren Z. Wang
  • Patent number: 10189820
    Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: January 29, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: John F. Mehlmann, Joseph J. Romano
  • Publication number: 20180105514
    Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
    Type: Application
    Filed: January 3, 2018
    Publication date: April 19, 2018
    Inventors: John F. MEHLMANN, Joseph J. ROMANO
  • Publication number: 20180085365
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 29, 2018
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Pamela A. HAILE, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Robert R. SINGHAUS, JR., Gren Z. WANG
  • Patent number: 9650364
    Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: May 16, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limted
    Inventors: Linda N. Casillas, Adam Kenneth Charnley, Xiaoyang Dong, Pamela A. Haile, Michael P. Demartino, John F. Mehlmann
  • Publication number: 20170128437
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 11, 2017
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Pamela A. HAILE, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Robert R. SINGHAUS, JR., Gren Z. WANG
  • Patent number: 9604963
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: March 28, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Pamela A. Haile, Robert W. Marquis, Jr., John F. Mehlmann, Joseph J. Romano, Robert R. Singhaus, Jr., Gren Z. Wang
  • Publication number: 20160060222
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Michael P. DeMARTINO, Xiaoyang DONG, Patrick EIDAM, Pamela A. HAILE, Philip Anthony HARRIS, Ami Lakdawala SHAH, Bryan W. KING, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Clark A. SEHON
  • Publication number: 20160060249
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 5, 2015
    Publication date: March 3, 2016
    Inventors: Linda N. CASILLAS, Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes, Robert W. Marquis, JR., John F. Mehlmann, Michael Reilly, Joseph J. Romano, Robert R. Singhaus, JR.
  • Patent number: 9216965
    Abstract: Disclosed are compounds having the formula: wherein R1, R2R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: December 22, 2015
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Linda N. Casillas, Michael P. Demartino, Pamela A. Haile, John F. Mehlmann, Joshi M. Ramanjulu, Robert Singhaus, Jr.
  • Publication number: 20150361069
    Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 17, 2015
    Inventors: Linda N. CASILLAS, Adam Kenneth CHARNLEY, Xiaoyang DONG, Pamela A. HAILE, Michael P. DEMARTINO, John F. MEHLMANN
  • Publication number: 20150094333
    Abstract: Disclosed are compounds having the formula: wherein R1, R2R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: September 13, 2013
    Publication date: April 2, 2015
    Inventors: Linda N. Casillas, Michael P. Demartino, Pamela A. Haile, John F. Mehlmann, Joshi M. Ramanjulu, Robert Singhaus, JR.
  • Publication number: 20140256949
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 11, 2014
    Applicant: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Linda N. CASILLAS, Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes, Robert W. Marquis, JR., John F. Mehlmann, Michael Reilly, Joseph J. Romano, Robert R. Singhaus, JR.
  • Publication number: 20130345258
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 2, 2012
    Publication date: December 26, 2013
    Applicant: Glaxosmithline LLC
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Pamela A. Haile, Robert W. Marquis, JR., John F. Mehlmann, Joseph J. Romano, Robert R. Singhaus, JR., Gren Z. Wang
  • Publication number: 20130053375
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 6, 2011
    Publication date: February 28, 2013
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Michael P. DeMartino, Xiaoyang Dong, Patrick Eidam, Pamela A. Haile, Philip Anthony Harris, Ami Lakdawala Shah, Bryan W. King, Robert W. Marquis, JR., John F. Mehlmann, Joseph J. Romano, Clark A. Sehon