Patents by Inventor John F. O'Connor
John F. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190104639Abstract: A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.Type: ApplicationFiled: December 3, 2018Publication date: April 4, 2019Inventors: John F. O'Connor, Roger B. Dickinson
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Patent number: 9541563Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: GrantFiled: March 28, 2014Date of Patent: January 10, 2017Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
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Publication number: 20160309616Abstract: A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.Type: ApplicationFiled: June 24, 2016Publication date: October 20, 2016Inventors: John F. O'Connor, Roger B. Dickinson
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Publication number: 20140212897Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: ApplicationFiled: March 28, 2014Publication date: July 31, 2014Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
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Patent number: 8691585Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: GrantFiled: June 1, 2011Date of Patent: April 8, 2014Assignee: The Trustees of Columbia University in the City of New YorkInventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
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Patent number: 8647051Abstract: An impeller for a centrifugal fan includes a hub, impeller blades, and struts for supporting the blades in a circumferential array spaced apart from the hub. The number of struts can equal the number of blades, each strut extended from the hub to support two blades while each blade is supported by one strut nearer to its leading edge and another strut nearer to its trailing edge. Another arrangement features two struts per blade, with one of the struts coupled to the hub and a given blade, and the other strut coupled between the given blade and an adjacent blade. The struts are recessed inwardly from the leading and trailing edges to promote smoother air flow. The blades and struts are provided with aerodynamic thickness profiles to further improve air flow.Type: GrantFiled: September 7, 2010Date of Patent: February 11, 2014Assignee: The Bergquist Torrington CompanyInventors: John F. O'Connor, Jan Najman, Michael C. Brauer
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Patent number: 8142147Abstract: A centrifugal blower having at least one radial plane dividing its scroll into sub-sections which may vary as to cut-off points and axial and radial dimensions as well as axial displacement to meet requirements of individual application system flow paths.Type: GrantFiled: April 9, 2008Date of Patent: March 27, 2012Assignee: The Bergquist Torrington CompanyInventors: John F. O'Connor, Roger B. Dickinson
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Publication number: 20110308777Abstract: A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.Type: ApplicationFiled: June 17, 2011Publication date: December 22, 2011Inventors: John F. O'Connor, Roger Dickinson
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Publication number: 20110280748Abstract: A centrifugal blower having at least one radial plane dividing its scroll into sub-sections which may vary as to cut-off points and axial and radial dimensions as well as axial displacement to meet requirements of individual application system flow paths.Type: ApplicationFiled: April 9, 2008Publication date: November 17, 2011Inventors: John F. O'Connor, JR., Roger B. Dickinson
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Publication number: 20110262938Abstract: The present invention provides a method for predicting the likely timing of the onset of menopause for a perimenopausal female subject by determining the amount of hLH?cf in a sample from the subject comprising the steps of: (a) contacting a sample from the subject with an antibody which specifically binds to hLH?cf without substantially cross-reacting with hLH, hLH? or hLH?cf, under conditions permitting formation of a complex between the antibody and hLH?cf; (b) measuring the amount of complex formed, so as to thereby determine the amount of hLH?cf in the sample; and (c) comprising the amount of hLH?cf in the subject's sample determined in step (b) with either (i) the amount determined for known postmenopausal female subject or (ii) the amount determined for a sample from a known premenopausal female subject, wherein an amount of hLH?cf in the sample similar to the amount of hLH?cf in the known postmenopausal sample indicates temporal proximity to the onset of menopause, and an amount of hLH?cf in the samplType: ApplicationFiled: February 1, 2010Publication date: October 27, 2011Inventors: Steven Birken, Yacov Maydelman, Galina I. Kovalevskaya, John F. O'Connor
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Publication number: 20110256554Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: ApplicationFiled: June 1, 2011Publication date: October 20, 2011Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
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Patent number: 7977104Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: GrantFiled: September 27, 2006Date of Patent: July 12, 2011Assignee: The Trustees of Columbia University in the City of New YorkInventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
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Publication number: 20110064570Abstract: An impeller for a centrifugal fan includes a hub, impeller blades, and struts for supporting the blades in a circumferential array spaced apart from the hub. The number of struts can equal the number of blades, each strut extended from the hub to support two blades while each blade is supported by one strut nearer to its leading edge and another strut nearer to its trailing edge. Another arrangement features two struts per blade, with one of the struts coupled to the hub and a given blade, and the other strut coupled between the given blade and an adjacent blade. The struts are recessed inwardly from the leading and trailing edges to promote smoother air flow. The blades and struts are provided with aerodynamic thickness profiles to further improve air flow.Type: ApplicationFiled: September 7, 2010Publication date: March 17, 2011Inventors: John F. O'Connor, Jan Najman, Michael C. Brauer
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Patent number: 7655410Abstract: The present invention provides a method for predicting the likely timing of the onset of menopause for a perimenopausal female subject by determining the amount of hLH?cf in a sample from the subject comprising the steps of: (a) contacting a sample from the subject with an antibody which specifically binds to hLH?cf without substantially cross-reacting with hLH, hLH? or hLH?cf, under conditions permitting formation of a complex between the antibody and hLH?cf; (b) measuring the amount of complex formed, so as to thereby determine the amount of hLH?cf in the sample; and (c) comprising the amount of hLH?cf in the subject's sample determined in step (b) with either (i) the amount determined for known postmenopausal female subject or (ii) the amount determined for a sample from a known premenopausal female subject, wherein an amount of hLH?cf in the sample similar to the amount of hLH?cf in the known postmenopausal sample indicates temporal proximity to the onset of menopause, and an amount of hLH?cf in the samplType: GrantFiled: February 10, 2003Date of Patent: February 2, 2010Assignee: The Trustees of Carolina University in the City of New YorkInventors: Steven Birken, Yacov Maydelman, Galina I. Kovalevskaya, John F. O'Connor
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Patent number: 7481108Abstract: A method is provided for balancing a rotating member having an annular balancing groove which is configured to receive and retain a balancing projectile. The method includes determining a circumaxial imbalance location, and firing a balancing projectile in timed relationship with the rotation of the member so that the balancing projectile enters the groove at the imbalance location. Such steps are repeated as required to cure additional points of imbalance.Type: GrantFiled: October 24, 2007Date of Patent: January 27, 2009Assignee: The Bergquist Torrington' CompanyInventors: Drew M. Rocky, John F. O'Connor, Jr., Russel H. Marvin
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Patent number: 7399636Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG is a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: GrantFiled: December 31, 2002Date of Patent: July 15, 2008Assignee: The Trustees of Columbia University in the City of New YorkInventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
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Patent number: 7347252Abstract: An improved centrifugal impeller having between 20 and 26 rearwardly curved blades blades, a ratio of blade annulus width to wheel radius between 0.31 and 0.37, and an inlet blade angle in the range 32° to 36° and a discharge blade angle in the range 36° to 40°.Type: GrantFiled: October 28, 2004Date of Patent: March 25, 2008Assignee: The Bergquist Torrington CompanyInventor: John F. O'Connor, Jr.
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Patent number: 7305905Abstract: A rotatable member is adapted for dynamic balancing by the addition of balancing weights in the form of high speed projectiles fired at the member during rotation in timed relationship with the rotation of the member so as to impact the member at specific circumaxial locations required for balancing the member. The member has an annular groove for receiving the projectiles and securing the same at the desired locations. The groove has a cross sectional configuration slightly smaller than that of the projectile in at least one direction of measurement so as to engage and capture the projectile in retention in the groove.Type: GrantFiled: January 9, 2004Date of Patent: December 11, 2007Assignee: The Bergquist Torrington CompanyInventors: Drew M. Rocky, Russel H. Marvin, John F. O'Connor, Jr.
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Patent number: 7229781Abstract: The present invention provides methods to quantitate the hLH? core fragment in a sample. The present invention now makes it possible to evaluate the metabolism of hLH in premenopausal, perimenopausal and postmenopausal women and to distinguish between normal and abnormal physiological states.Type: GrantFiled: May 31, 2002Date of Patent: June 12, 2007Assignee: The Trustees of Columbia University in the City of New YorkInventors: Steven Birken, Yacov Maydelman, Galina I. Kovalevskaya, John F. O'Connor
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Patent number: 7198954Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.Type: GrantFiled: August 1, 2000Date of Patent: April 3, 2007Assignee: The Trustees of Columbia University in the City of New YorkInventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken