Patents by Inventor John F. O'Connor

John F. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190104639
    Abstract: A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.
    Type: Application
    Filed: December 3, 2018
    Publication date: April 4, 2019
    Inventors: John F. O'Connor, Roger B. Dickinson
  • Patent number: 9541563
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: January 10, 2017
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
  • Publication number: 20160309616
    Abstract: A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.
    Type: Application
    Filed: June 24, 2016
    Publication date: October 20, 2016
    Inventors: John F. O'Connor, Roger B. Dickinson
  • Publication number: 20140212897
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
  • Patent number: 8691585
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: April 8, 2014
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
  • Patent number: 8647051
    Abstract: An impeller for a centrifugal fan includes a hub, impeller blades, and struts for supporting the blades in a circumferential array spaced apart from the hub. The number of struts can equal the number of blades, each strut extended from the hub to support two blades while each blade is supported by one strut nearer to its leading edge and another strut nearer to its trailing edge. Another arrangement features two struts per blade, with one of the struts coupled to the hub and a given blade, and the other strut coupled between the given blade and an adjacent blade. The struts are recessed inwardly from the leading and trailing edges to promote smoother air flow. The blades and struts are provided with aerodynamic thickness profiles to further improve air flow.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: February 11, 2014
    Assignee: The Bergquist Torrington Company
    Inventors: John F. O'Connor, Jan Najman, Michael C. Brauer
  • Patent number: 8142147
    Abstract: A centrifugal blower having at least one radial plane dividing its scroll into sub-sections which may vary as to cut-off points and axial and radial dimensions as well as axial displacement to meet requirements of individual application system flow paths.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: March 27, 2012
    Assignee: The Bergquist Torrington Company
    Inventors: John F. O'Connor, Roger B. Dickinson
  • Publication number: 20110308777
    Abstract: A cooling fan module for motivating air flow through an electronics chassis includes an enclosure having an air inlet through which cooling air flow is motivated by at least two centrifugal blowers disposed within the enclosure. The centrifugal blowers operate in parallel to motivate the cooling air flow along a first direction vector, while the respective axes of rotation of the centrifugal blower impellers are in substantial axial alignment with one another, and parallel to the first direction vector.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 22, 2011
    Inventors: John F. O'Connor, Roger Dickinson
  • Publication number: 20110280748
    Abstract: A centrifugal blower having at least one radial plane dividing its scroll into sub-sections which may vary as to cut-off points and axial and radial dimensions as well as axial displacement to meet requirements of individual application system flow paths.
    Type: Application
    Filed: April 9, 2008
    Publication date: November 17, 2011
    Inventors: John F. O'Connor, JR., Roger B. Dickinson
  • Publication number: 20110262938
    Abstract: The present invention provides a method for predicting the likely timing of the onset of menopause for a perimenopausal female subject by determining the amount of hLH?cf in a sample from the subject comprising the steps of: (a) contacting a sample from the subject with an antibody which specifically binds to hLH?cf without substantially cross-reacting with hLH, hLH? or hLH?cf, under conditions permitting formation of a complex between the antibody and hLH?cf; (b) measuring the amount of complex formed, so as to thereby determine the amount of hLH?cf in the sample; and (c) comprising the amount of hLH?cf in the subject's sample determined in step (b) with either (i) the amount determined for known postmenopausal female subject or (ii) the amount determined for a sample from a known premenopausal female subject, wherein an amount of hLH?cf in the sample similar to the amount of hLH?cf in the known postmenopausal sample indicates temporal proximity to the onset of menopause, and an amount of hLH?cf in the sampl
    Type: Application
    Filed: February 1, 2010
    Publication date: October 27, 2011
    Inventors: Steven Birken, Yacov Maydelman, Galina I. Kovalevskaya, John F. O'Connor
  • Publication number: 20110256554
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Application
    Filed: June 1, 2011
    Publication date: October 20, 2011
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
  • Patent number: 7977104
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: July 12, 2011
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
  • Publication number: 20110064570
    Abstract: An impeller for a centrifugal fan includes a hub, impeller blades, and struts for supporting the blades in a circumferential array spaced apart from the hub. The number of struts can equal the number of blades, each strut extended from the hub to support two blades while each blade is supported by one strut nearer to its leading edge and another strut nearer to its trailing edge. Another arrangement features two struts per blade, with one of the struts coupled to the hub and a given blade, and the other strut coupled between the given blade and an adjacent blade. The struts are recessed inwardly from the leading and trailing edges to promote smoother air flow. The blades and struts are provided with aerodynamic thickness profiles to further improve air flow.
    Type: Application
    Filed: September 7, 2010
    Publication date: March 17, 2011
    Inventors: John F. O'Connor, Jan Najman, Michael C. Brauer
  • Patent number: 7655410
    Abstract: The present invention provides a method for predicting the likely timing of the onset of menopause for a perimenopausal female subject by determining the amount of hLH?cf in a sample from the subject comprising the steps of: (a) contacting a sample from the subject with an antibody which specifically binds to hLH?cf without substantially cross-reacting with hLH, hLH? or hLH?cf, under conditions permitting formation of a complex between the antibody and hLH?cf; (b) measuring the amount of complex formed, so as to thereby determine the amount of hLH?cf in the sample; and (c) comprising the amount of hLH?cf in the subject's sample determined in step (b) with either (i) the amount determined for known postmenopausal female subject or (ii) the amount determined for a sample from a known premenopausal female subject, wherein an amount of hLH?cf in the sample similar to the amount of hLH?cf in the known postmenopausal sample indicates temporal proximity to the onset of menopause, and an amount of hLH?cf in the sampl
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: February 2, 2010
    Assignee: The Trustees of Carolina University in the City of New York
    Inventors: Steven Birken, Yacov Maydelman, Galina I. Kovalevskaya, John F. O'Connor
  • Patent number: 7481108
    Abstract: A method is provided for balancing a rotating member having an annular balancing groove which is configured to receive and retain a balancing projectile. The method includes determining a circumaxial imbalance location, and firing a balancing projectile in timed relationship with the rotation of the member so that the balancing projectile enters the groove at the imbalance location. Such steps are repeated as required to cure additional points of imbalance.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: January 27, 2009
    Assignee: The Bergquist Torrington' Company
    Inventors: Drew M. Rocky, John F. O'Connor, Jr., Russel H. Marvin
  • Patent number: 7399636
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG is a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: July 15, 2008
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken
  • Patent number: 7347252
    Abstract: An improved centrifugal impeller having between 20 and 26 rearwardly curved blades blades, a ratio of blade annulus width to wheel radius between 0.31 and 0.37, and an inlet blade angle in the range 32° to 36° and a discharge blade angle in the range 36° to 40°.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: March 25, 2008
    Assignee: The Bergquist Torrington Company
    Inventor: John F. O'Connor, Jr.
  • Patent number: 7305905
    Abstract: A rotatable member is adapted for dynamic balancing by the addition of balancing weights in the form of high speed projectiles fired at the member during rotation in timed relationship with the rotation of the member so as to impact the member at specific circumaxial locations required for balancing the member. The member has an annular groove for receiving the projectiles and securing the same at the desired locations. The groove has a cross sectional configuration slightly smaller than that of the projectile in at least one direction of measurement so as to engage and capture the projectile in retention in the groove.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: December 11, 2007
    Assignee: The Bergquist Torrington Company
    Inventors: Drew M. Rocky, Russel H. Marvin, John F. O'Connor, Jr.
  • Patent number: 7229781
    Abstract: The present invention provides methods to quantitate the hLH? core fragment in a sample. The present invention now makes it possible to evaluate the metabolism of hLH in premenopausal, perimenopausal and postmenopausal women and to distinguish between normal and abnormal physiological states.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: June 12, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Steven Birken, Yacov Maydelman, Galina I. Kovalevskaya, John F. O'Connor
  • Patent number: 7198954
    Abstract: The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: April 3, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: John F. O'Connor, Galina I. Kovalevskaya, Steven Birken