Patents by Inventor John Faulkner

John Faulkner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kinesin motor modulators derived from the marine sponge Adocia
    Patent number: 6207403
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: March 27, 2001
    Assignee: The Regents of the University of California
    Inventors: Lawrence S. B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann
  • Manoalide analogs
    Patent number: 4952605
    Abstract: Analogs of the marine natural product manoalide are useful in treating mammals, including humans, in need of a drug having analgesic/anti-inflammatory, immunosuppressive, and/or antiproliferative activity.
    Type: Grant
    Filed: November 18, 1988
    Date of Patent: August 28, 1990
    Assignee: The Regents of the University of California
    Inventors: Robert S. Jacobs, D. John Faulkner
  • Manoalide analogs
    Patent number: 4789749
    Abstract: Analogs of the marine natural product manoalide are useful in treating mammals, including humans, in need of a drug having analgesic/anti-inflammatory, immunosuppressive, and/or antiproliferative activity.
    Type: Grant
    Filed: February 19, 1986
    Date of Patent: December 6, 1988
    Assignee: The Regents of the University of California
    Inventors: Robert S. Jacobs, D. John Faulkner
  • Synthetic anti-inflammatory derivatives of manoalide
    Patent number: 4616089
    Abstract: Synthetic analogs of the marine natural product manoalide include 3,7-Bis(hydroxymethyl)-4-hydroxy-11-methyl-13-(2',6',6'-trimethylcyclohexe nyl)-2,6,10-tridecatrienoic acid .gamma.-lactone, manoalide .delta.-lactone, manoalide .delta.-lactone acetate and dehydro-seco-manoalide.The method of treating mammals including humans in need of a drug having analgesic and/or anti-inflammatory activity comprising the administration of a therapeutically effective amount of a synthetic analog of manoalide.
    Type: Grant
    Filed: June 18, 1984
    Date of Patent: October 7, 1986
    Assignee: University of California
    Inventors: Robert S. Jacobs, D. John Faulkner
  • Manoalide, an anti-inflammatory analgesic marine natural product
    Patent number: 4447445
    Abstract: The method of treating mammals including humans in need of a drug having analgesic and/or anti-inflammatory activity comprising the administration of a therapeutically effective amount of manoalide, seco-manoalide or dehydro-seco-manoalide. The anti-inflammatory utility includes acute, chronic and delayed sensitization inflammatory processes.
    Type: Grant
    Filed: August 3, 1983
    Date of Patent: May 8, 1984
    Assignee: The Regents of the University of Calif.
    Inventors: Robert S. Jacobs, D. John Faulkner
  • Sceptrin an antimicrobial agent from Agelas sceptrum
    Patent number: 4370484
    Abstract: A novel antimicrobial agent having the formula: ##STR1## The new antimicrobial agent may exist as the dihydrochloride salt, as shown or as tautomers of the structure, or in the form of other salts and derivatives such as amides and is normally associated with water of crystallization.The novel antimicrobial agent is obtained from Agelas sceptrum, Agelas conifera, Agelas schmidti, an unknown sponge species from Canton atoll and an unknown sponge Axinella sp., from Belize.
    Type: Grant
    Filed: March 12, 1981
    Date of Patent: January 25, 1983
    Assignee: The Regents of the University of California
    Inventor: D. John Faulkner