Abstract: An automation apparatus and method includes a first unit rotationally moving objects from one area to another, and a second unit connected to the first unit and holding the objects, moving through or offset from the body of the first unit from a first side of the first unit to the other side the first unit in a direction other than the rotational movement by the first unit. Moreover, the apparatus and method provides moving the objects through a vertical axis of the body of the first unit.

Abstract: A superalloy composition comprising, in weight percent: about 6.2-6.6 Al, about 6.5-7.0 Ta, about 6.0-7.0 Cr, about 6.25-7.0 W, about 1.5-2.5 Mo, about 0.15-0.60 Hf, 0.0-1.0 Re, 6.5-9.0 Co, optionally, 0.03-0.06 C, optionally, up to about 0.004 B, optionally up to about 0.03 total of one or more rare earth elements selected from yttrium (Y), lanthanum (La), or cerium (Ce), balance nickel, such that the superalloy composition exhibits a stress rupture capability improvement of at least 15% over a base stress rupture capability of a base composition nominally comprising, in weight percent: 6.5 Al, 6.6 Ta, 6.0 Cr, 6.25 W, 1.5 Mo, 0.15 Hf, 0.0 Re, 7.5 Co. Articles incorporating the superalloy composition include a gas turbine engine component such as a high pressure turbine nozzle or nozzle segment.

Abstract: An automation apparatus and method includes a first unit rotationally moving objects from one area to another, and a second unit connected to the first unit and holding the objects, moving through or offset from the body of the first unit from a first side of the first unit to the other side the first unit in a direction other than the rotational movement by the first unit. Moreover, the apparatus and method provides moving the objects through a vertical axis of the body of the first unit.

Abstract: The present invention relates to novel substrates, to methods of making them and to uses therefor. The substrates of the invention comprise a base portion and a surface layer covering at least part of the base portion, with a binding layer provided therebetween. The surface layer provides, on at least a part of the substrate, topographical features having at least one nano scale dimension. These topographical features are adapted to facilitate, influence, control or inhibit cell or tissue growth thereon and/or therebetween and the substrate may be used for the study, manipulation or modification of at least one cellular or tissue behavior or response.

Abstract: The present invention relates to novel substrates, to methods of making them and to uses therefor. The substrates of the invention comprise a base portion and a surface layer covering at least part of the base portion, with a binding layer provided therebetween. The surface layer provides, on at least a part of the substrate, topographical features having at least one nano scale dimension. These topographical features are adapted to inhibit cell or tissue growth thereon and/or therebetween.

Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.

Abstract: The present invention relates to the NTE proteins and nucleic acids encoding the NTE proteins. The present invention further provides assays for the detection of NTE polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NTE proteins.

Abstract: A rebond polyurethane foam structure is formed by mixing shredded particles of polyurethane foam wherein at least 20% by weight of such particles comprise particles of viscoelastic polyurethane foam. The foam particles are wetted with a liquid prepolymer binder that is cured when the wetted admixture is compressed at a compression ratio of at least about 3. Despite the small viscoelastic foam particle size and the effects of compression and binder curing, the resulting polyurethane foam structure surprisingly has a viscoelastic (slow recovery) character.

Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.

Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.

Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.

Abstract: The present invention relates to novel substrates, to methods of making them and to uses therefor. The substrates of the invention comprise a base portion and a surface layer covering at least part of the base portion, with a binding layer provided therebetween. The surface layer provides, on at least a part of the substrate, topographical features having at least one nano scale dimension. These topographical features are adapted to facilitate, influence, control or inhibit cell or tissue growth thereon and/or therebetween and the substrate may be used for the study, manipulation or modification of at least one cellular or tissue behaviour or response.

Abstract: The invention concerns the use of a biomaterial substrate to orient cell or tissue growth. The substrate comprises a base portion and a surface layer covering at least part of the base portion. The surface layer provides the substrate with topographical features having at least one nanoscale dimension of from about 1 to about 200 nm. The topographical features having the capacity to orient cell or tissue growth thereon and/or therebetween.

Abstract: A gas turbine engine includes a blade including a leading edge, a trailing edge, a first sidewall extending in radial span between a blade root and blade tip, and a second sidewall connected to the first sidewall at the leading edge and at the trailing edge. The first and second sidewalls each include an outer surface and an inner surface. A cooling cavity is defined by the first sidewall inner surface and the second sidewall inner surface. At least a portion of the cooling cavity is coated with an oxidation resistant environmental coating that has a thickness less than 0.0015 inches.

Abstract: A gas turbine engine includes a blade including a leading edge, a trailing edge, a first sidewall extending in radial span between a blade root and blade tip, and a second sidewall connected to the first sidewall at the leading edge and at the trailing edge. The first and second sidewalls each include an outer surface and an inner surface. A cooling cavity is defined by the first sidewall inner surface and the second sidewall inner surface. At least a portion of the cooling cavity is coated with an oxidation resistant environmental coating that has a thickness less than 0.0015 inches.

Abstract: A safety lock device including a clover mechanism mounted on a rotating shaft to be used with an unbalanced free-fall dog that precludes rotation of the rotating shaft upon rapid acceleration or excessive speed of the rotation of the shaft. The free-fall dog is pivotally mounted on a fulcrum upon which the free-fall dog may teeter in an unbalanced seesaw motion. At opposite ends of the fulcrum are a locking finger and an arm. The free-fall dog is unbalanced such that the arm contacts the clover mechanism as it rotates while the locking finger does not contact the clover mechanism at slow rotating speed. At a slow rotative speed, the arm is only slightly deflected. With great acceleration, the arm is deflected farther from the clover mechanism thereby causing the locking finger on the opposite side of the fulcrum to be pivoted into the clover mechanism.

Abstract: A battery operated, rotatable platform display device for use in retail establishments. The display device employs a friction clutch provided between the base of the rotatable platform and an underlying drive plate upon which the rotatable platform is supported via a rotatable drive shaft.

Abstract: A heel support for supporting an person's extremity includes an inflatable air bag having three panels, a middle panel and two side panels. An upper surface of the middle panel has a smaller radius of curvature than upper surfaces of the side panels. The panels are connected together in a manner which allows the two side panels to collapse inwardly toward the bottom panel. The side panels fold inwardly toward one another and are secured by an attachment means, preferably hook-and-loop strips.