Patents by Inventor John Fitzgerald Kokai-Kun

John Fitzgerald Kokai-Kun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria
    Patent number: 7169903
    Abstract: The present invention encompasses protective monoclonal antibodies that bind to peptidoglycan of Gram-positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro and block nasal colonization by Gram-positive bacteria in vivo. The invention also provides human, humanized and chimeric antibodies. The invention also sets forth the heavy chain and light chain variable regions of an antibody within the invention.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: January 30, 2007
    Assignee: Biosynexus Incorporated
    Inventors: Richard F. Schuman, John Fitzgerald Kokai-Kun, Simon J. Foster, Jeffrey R. Stinson, Gerald Walter Fischer
  • Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
    Publication number: 20040247605
    Abstract: This invention provides vaccines comprising staphylococcal wall teichoic acid (WTA); vaccines comprising antibodies that specifically bind WTA; staphylococcal organisms deficient in WTA; and methods of treating patients suspected of having a staphylococcal infection.
    Type: Application
    Filed: December 1, 2003
    Publication date: December 9, 2004
    Inventors: John Fitzgerald Kokai-Kun, Andreas Peschel, Christopher Weidenmaier, Sascha A. Kristian
  • Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria
    Publication number: 20030228322
    Abstract: The present invention encompasses protective monoclonal antibodies that bind to peptidoglycan of Gram-positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro and block nasal colonization by Gram-positive bacteria in vivo. The invention also provides human, humanized and chimeric antibodies. The invention also sets forth the heavy chain and light chain variable regions of an antibody within the invention.
    Type: Application
    Filed: December 20, 2002
    Publication date: December 11, 2003
    Inventors: Richard F. Schuman, John Fitzgerald Kokai-Kun, Simon J. Foster, Jeffrey R. Stinson, Gerald Walter Fischer
  • Methods for blocking or alleviating staphylococcal nasal colonization by intranasal application of monoclonal antibodies
    Publication number: 20030224000
    Abstract: This invention provides MAbs for blocking and alleviating nasal colonization by staphylococci and methods for their use in the anterior nares.
    Type: Application
    Filed: December 20, 2002
    Publication date: December 4, 2003
    Inventors: John Fitzgerald Kokai-Kun, Jeffrey Richard Stinson, Scott Michael Walsh, Andrew Lees, James J. Mond, Gerald Walter Fischer
  • Methods and formulations for eradicating or alleviating staphylococcal nasal colonization using lysostaphin
    Publication number: 20030211995
    Abstract: This invention provides lysostaphin intranasal compositions that can be administered to the anterior nares of those at risk for staphylococcal nasal colonization and subsequent infection and methods for their use.
    Type: Application
    Filed: December 20, 2002
    Publication date: November 13, 2003
    Inventors: John Fitzgerald Kokai-Kun, Scott Michael Walsh, James Jacob Mond, Tatyana Ivanovna Chanturiya