Patents by Inventor John Francis McElroy

John Francis McElroy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers
    Patent number: 8680131
    Abstract: The present invention provides novel, diastereomeric pyrazolines that are useful as cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, inflammatory disorders, cardiometabolic disorders, hepatic disorders, and/or cancers.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: March 25, 2014
    Assignee: Jenrin Discovery, Inc.
    Inventors: John Francis McElroy, Robert John Chorvat
  • MAO-B inhibitors useful for treating obesity
    Patent number: 8541475
    Abstract: The invention provides novel compounds of formulae I and II: that are monoamine oxidase-B inhibitors, which can be useful in treating obesity, diabetes, and/or cardiometabolic disorders (e.g., hypertension, dyslipidemias, high blood pressure, and insulin resistance).
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: September 24, 2013
    Assignee: Jenrin Discovery, Inc.
    Inventors: John Francis McElroy, Robert J. Chorvat, Parthasarathi Rajagopalan
  • Substituted picolinamides as MAO-B inhibitors useful for treating obesity
    Patent number: 8138209
    Abstract: The invention provides novel compounds of formula I: that are monoamine oxidase-B inhibitors, which can be useful in treating obesity, diabetes, and/or cardiometabolic disorders (e.g., hypertension, dyslipidemias, high blood pressure, and insulin resistance).
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: March 20, 2012
    Assignee: Jenrin Discovery, Inc.
    Inventors: John Francis McElroy, Robert J. Chorvat, Rajagopalan Parthasarathi
  • MAO-B INHIBITORS USEFUL FOR TREATING OBESITY
    Publication number: 20120015909
    Abstract: The invention provides novel compounds of formulae I and II: that are monoamine oxidase-B inhibitors, which can be useful in treating obesity, diabetes, and/or cardiometabolic disorders (e.g., hypertension, dyslipidemias, high blood pressure, and insulin resistance).
    Type: Application
    Filed: March 30, 2011
    Publication date: January 19, 2012
    Applicant: JENRIN DISCOVERY
    Inventors: John Francis McElroy, Robert J. Chorvat, Parthasarathi Rajagopalan
  • Cannabinoid receptor antagonists/inverse agonists useful for treating obesity
    Patent number: 8088798
    Abstract: The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, and/or cardiometabolic disorders.
    Type: Grant
    Filed: February 6, 2010
    Date of Patent: January 3, 2012
    Assignee: Jensen Discovery, Inc.
    Inventors: John Francis McElroy, Robert J. Chorvat
  • MAO-B inhibitors useful for treating obesity
    Patent number: 7956220
    Abstract: The invention provides novel compounds of formulae I and II: that are monoamine oxidase-B inhibitors, which can be useful in treating obesity, diabetes, and/or cardiometabolic disorders (e.g., hypertension, dyslipidemias, high blood pressure, and insulin resistance).
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: June 7, 2011
    Assignee: Jenrin Discovery
    Inventors: John Francis McElroy, Robert J. Chorvat, Rajagopalan Parthasarathi
  • MAO-B INHIBITORS USEFUL FOR TREATING OBESITY
    Publication number: 20100168068
    Abstract: The invention provides novel compounds of formulae I and II: that are monoamine oxidase-B inhibitors, which can be useful in treating obesity, diabetes, and/or cardiometabolic disorders (e.g., hypertension, dyslipidemias, high blood pressure, and insulin resistance).
    Type: Application
    Filed: December 31, 2009
    Publication date: July 1, 2010
    Applicant: JENRIN DISCOVERY
    Inventors: John Francis McElroy, Robert J. Chorvat, Parthasarathi Rajagopalan
  • CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY
    Publication number: 20100144791
    Abstract: The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, and/or cardiometabolic disorders.
    Type: Application
    Filed: February 6, 2010
    Publication date: June 10, 2010
    Applicant: JENRIN DISCOVERY
    Inventors: John Francis McElroy, Robert J. Chorvat
  • Cannabinoid receptor antagonists/inverse agonists useful for treating obesity
    Patent number: 7687481
    Abstract: The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, and/or cardiometabolic disorders.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: March 30, 2010
    Assignee: Jenrin Discovery, Inc.
    Inventors: John Francis McElroy, Robert J. Chorvat
  • MAO-B inhibitors useful for treating obesity
    Patent number: 7649115
    Abstract: The invention provides novel compounds of formulae I and II: that are monoamine oxidase-B inhibitors, which can be useful in treating obesity, diabetes, and/or cardiometabolic disorders (e.g., hypertension, dyslipidemias, high blood pressure, and insulin resistance).
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: January 19, 2010
    Assignee: Jenrin Discovery, Inc.
    Inventors: John Francis McElroy, Robert J. Chorvat, Parthasarathi Rajagopalan
  • Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes
    Patent number: 7482470
    Abstract: The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, and/or cardiometabolic disorders.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: January 27, 2009
    Assignee: Jenrin Discovery, Inc.
    Inventors: John Francis McElroy, Robert John Chorvat
  • CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES
    Publication number: 20070259934
    Abstract: The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, and/or cardiometabolic disorders.
    Type: Application
    Filed: May 7, 2007
    Publication date: November 8, 2007
    Applicant: JENRIN DISCOVERY
    Inventors: John Francis McElroy, Robert John Chorvat
  • CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY
    Publication number: 20070213302
    Abstract: The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, and/or cardiometabolic disorders.
    Type: Application
    Filed: March 9, 2007
    Publication date: September 13, 2007
    Applicant: JENRIN DISCOVERY
    Inventors: John Francis McElroy, Robert J. Chorvat
  • 5-HT7 receptor antagonists
    Patent number: 6486173
    Abstract: The present invention relates to compounds having pharmacological activity toward the 5-HT7 receptor. Pharmaceutical compositions and methods for their use in the treatment of CNS disorders are described.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: November 26, 2002
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Gary Avonn Cain, John Francis McElroy
  • 5-HT7 receptor antagonists
    Patent number: 6239143
    Abstract: The present invention relates to compounds having pharmacological activity toward the 5-HT7 receptor. Pharmaceutical compositions and methods for their use in the treatment of CNS disorders are described.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: May 29, 2001
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Gary Avonn Cain, John Francis McElroy