Patents by Inventor John Frederick Cavalla

John Frederick Cavalla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4061640
    Abstract: Compounds of the formula ##STR1## in which W is quinolyl or lower alkyl quinolyl;A is alkylene of 1 to 6 carbon atoms;R is phenyl, halophenyl, lower alkoxy phenyl or lower alkyl phenyl;Or a pharmaceutically acceptable acid addition salt thereof, are hypotensive and bradycardial agents.
    Type: Grant
    Filed: July 29, 1976
    Date of Patent: December 6, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald
  • Patent number: 4046767
    Abstract: Novel piperidine compounds and their use in treatment of disorders and diseases of the cardiovascular system and/or in the treatment of superficial and deep allergic phenomena is described. These compounds are piperidine compounds linked by the nitrogen atom to cycloalkyl or a substituted or unsubstituted phenyl radical through the intermediary of a lower-alkylene radical. The piperidine ring is further substituted by an acylamino residue.
    Type: Grant
    Filed: June 16, 1976
    Date of Patent: September 6, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald
  • Patent number: 4045444
    Abstract: A group of heterocyclic compounds useful in the treatment of disorders and diseases of the cardiovascular system is described. These compounds are piperidine compounds linked by the nitrogen atom to a methylenedioxyphenyl or an ethylenedioxyphenyl radical through the intermediary of a group selected from a mono-keto lower alkylene radical or a hydroxy-lower-alkylene radical or a bivalent radical of the formula ##STR1## or --O--(lower alkylene). The piperidine rings are further substituted by a benzamido residue.
    Type: Grant
    Filed: April 20, 1976
    Date of Patent: August 30, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald
  • Patent number: 4029801
    Abstract: Pharmaceutical compositions containing a group of heterocyclic compounds and their use in treatment of disorders and diseases of the cardiovascular system and/or in the treatment of superficial and deep allergic phenomena is described. These compounds used in the composition and/or methods are piperidine compounds linked by the nitrogen atom to a substituted or unsubstituted cycloalkyl, aryl or heterocyclic radical through the intermediary of a group selected from a lower-alkylene radical, a monoketo lower-alkylene radical or a hydroxy-lower-alkylene radical, or a bivalent radical of the formula --NH.CO.(CH.sub.2).sub.n -- where n is 1, 2 or 3, ##STR1## or --0-(lower-alkylene)--. The piperidine ring is further substituted by an acylamino residue.
    Type: Grant
    Filed: April 2, 1975
    Date of Patent: June 14, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald
  • Patent number: 4028365
    Abstract: A group of benz[g]indolyl compounds useful in the treatment of disorders and diseases of the cardiovascular system is described. These are piperidine compounds linked by the nitrogen atom to a substituted or unsubstituted benz[g]indolyl radical through the intermediary of a lower-alkylene radical. The piperidine rings are further substituted by an acylamino residue.
    Type: Grant
    Filed: November 15, 1974
    Date of Patent: June 7, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald
  • Patent number: 4028352
    Abstract: A group of heterocyclic compounds useful in the treatment of disorders and diseases of the cardiovascular system is described. These compounds are piperidine compounds linked by the nitrogen atom to a halogen-substituted or unsubstituted phenyl radical through the intermediary of a ##STR1## GROUP WHEREIN N IS AN INTEGER FROM 1 TO 4, AND Ar represents phenyl or halophenyl. The piperidine rings are further substituted by a benzamido residue.
    Type: Grant
    Filed: April 20, 1976
    Date of Patent: June 7, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald
  • Patent number: 3992389
    Abstract: A group of heterocyclic compounds useful in the treatment of disorders and diseases of the cardiovascular system and/or in the treatment of superficial and deep allergic phenomena is described. These compounds are piperidine compounds linked by the nitrogen atom to a substituted or unsubstituted phenyl radical through the intermediary of a group selected from a lower-alkylene radical, a mono-keto lower alkylene radical or a hydroxy-lower-alkylene radical, or a bivalent radical of the formula ##EQU1## or --O--(lower-alkylene)-. The piperidine rings are further substituted by a benzamido, substituted benzamido or cyclohexylcarboxamido residue.
    Type: Grant
    Filed: April 2, 1975
    Date of Patent: November 16, 1976
    Assignee: John Wyeth & Brother Limited
    Inventors: John Frederick Cavalla, John Leheup Archibald