Patents by Inventor John Friedewald

John Friedewald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE EXPRESSION PROFILES ASSOCIATED WITH SUB-CLINICAL KIDNEY TRANSPLANT REJECTION
    Publication number: 20240410007
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Application
    Filed: June 24, 2024
    Publication date: December 12, 2024
    Inventors: Daniel Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Todd Ordoukhanian
  • Gene expression profiles associated with sub-clinical kidney transplant rejection
    Patent number: 12060611
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: August 13, 2024
    Assignees: THE SCRIPPS RESEARCH INSTITUTE, NORTHWESTERN UNIVERSITY
    Inventors: Daniel Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Ordoukhanian
  • Methods, Systems, and Compositions for Diagnosing Transplant Rejection
    Publication number: 20240191301
    Abstract: Described herein are methods, compositions, and systems useful for detecting transplant rejection and associated abnormal conditions in solid organ transplant recipients, such as kidney transplant recipients. Methods described herein may involve combined assessment of blood gene expression profiles from an assessment of particular, related mRNA transcript levels and donor-derived cell-free nucleic acids (dd-cfDNA).
    Type: Application
    Filed: January 26, 2024
    Publication date: June 13, 2024
    Applicants: Northwestern University, Transplant Genomics, Inc., The Scripps Research Institute
    Inventors: John Friedewald, Michael M. Abecassis, Rohita Sinha, Sook Hyeon Park, Lihui Zhao, Juston Weems, Sunil M. Kurian, Steve Kleiboeker
  • GENE EXPRESSION PROFILES ASSOCIATED WITH SUB-CLINICAL KIDNEY TRANSPLANT REJECTION
    Publication number: 20200208217
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Application
    Filed: September 12, 2019
    Publication date: July 2, 2020
    Inventors: Daniel Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Ordoukhanian
  • Gene expression profiles associated with sub-clinical kidney transplant rejection
    Patent number: 10443100
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: October 15, 2019
    Assignee: The Scripps Research Institute
    Inventors: Daniel R. Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Ordoukhanian
  • GENE EXPRESSION PROFILES ASSOCIATED WITH SUB-CLINICAL KIDNEY TRANSPLANT REJECTION
    Publication number: 20170137885
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Application
    Filed: November 22, 2016
    Publication date: May 18, 2017
    Inventors: Daniel R. Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steven Head, Phillip Ordoukhanian