Patents by Inventor John G. Geisler

John G. Geisler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND THEIR USES DIRECTED TO ACEYTL-COA CARBOXYLASES
    Publication number: 20130109849
    Abstract: Disclosed herein are compounds, compositions and methods for modulating the expression of ACC1 or ACC2 or both in a cell, tissue or animal. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 2, 2013
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Sanjay Bhanot, Brett P. Monia, John G. Geisler, Robert McKay, Kenneth W. Dobie
  • Compositions and their uses directed to acetyl-CoA carboxylases
    Patent number: 8299041
    Abstract: Disclosed herein are compounds, compositions and methods for modulating the expression of ACC1 or ACC2 or both in a cell, tissue or animal. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: October 30, 2012
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Sanjay Bhanot, Brett P. Monia, John G. Geisler, Robert McKay, Kenneth W. Dobie
  • ANTISENSE MODULATION OF STEAROYL-COA DESATURASE EXPRESSION
    Publication number: 20110213136
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Sanjay Bhanot, Kenneth W. Dobie, John G. Geisler, Mark J. Graham
  • Antisense modulation of stearoyl-CoA desaturase expression
    Patent number: 7960358
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: June 14, 2011
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Sanjay Bhanot, Kenneth W. Dobie, John G. Geisler, Mark J. Graham
  • Antisense modulation of stearoyl-CoA desaturase expression
    Publication number: 20080153766
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
    Type: Application
    Filed: December 19, 2006
    Publication date: June 26, 2008
    Inventors: Sanjay Bhanot, Kenneth W. Dobie, John G. Geisler, Mark J. Graham