Abstract: The invention provides an indazole derivative of formula (1), or a pharmaceutically acceptable salt or N-oxide thereof, wherein R1, R2, R3 and R4 are as defined herein. The indazole derivatives are capable of blockading voltage dependent sodium channels and they are useful in the treatment or prevention of normal tension glaucoma, multiple sclerosis, a motorneurone disease, stroke, spinal cord injury, Alzheimer's disease, Parkinson's disease or pain.

Abstract: A fluid level switch for a machine having a fluid reservoir adapted to contain a fluid at an acceptable level. The fluid level switch includes a mounting plate, a float housing, and a float assembly positioned within the float housing. The mounting plate retains first and second contacts. The float housing is configured to receive fluid from the fluid reservoir and the float assembly is movable in response to the level of fluid in the float housing. The float assembly includes a contact member electrically connecting the first and second contacts when the level of the fluid is below the acceptable level. The contact member is coupled to the float for movement with the float and for movement relative to the float.

Abstract: A tube for directing fluid along a path that includes a bend. The tube comprising a conduit having a first aperture, a second aperture, and a bend portion adjacent the second aperture. An outer bend surface is integrally formed as part of the conduit to at least partially define the second aperture. An insert includes at least a portion of an inner bend surface and is disposed at least partially within the second aperture such that the outer bend surface and the inner bend surface cooperate to at least partially define the bend.

Abstract: A fluid level switch for a machine having a fluid reservoir adapted to contain a fluid at an acceptable level. The fluid level switch includes a mounting plate, a float housing, and a float assembly positioned within the float housing. The mounting plate retains first and second contacts. The float housing is configured to receive fluid from the fluid reservoir and the float assembly is movable in response to the level of fluid in the float housing. The float assembly includes a contact member electrically connecting the first and second contacts when the level of the fluid is below the acceptable level. The contact member is coupled to the float for movement with the float and for movement relative to the float.

Abstract: A tube for directing fluid along a path that includes a bend. The tube comprising a conduit having a first aperture, a second aperture, and a bend portion adjacent the second aperture. An outer bend surface is integrally formed as part of the conduit to at least partially define the second aperture. An insert includes at least a portion of an inner bend surface and is disposed at least partially within the second aperture such that the outer bend surface and the inner bend surface cooperate to at least partially define the bend.