Patents by Inventor John Geigert
John Geigert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4937191Abstract: A method producing a non-heme haloperoxidase which is substantially resistant to inactivation, at room temperature, in up to 0.3M H.sub.2 O.sub.2 for up to 25 hours, and up to 0.5mM HOCl for up to two minutes. One such haloperoxidase, isolated from Curvularia inaequalis, contains about 2 gram atoms of zinc per molecule. A halogenation reaction employing the enzyme can be performed at H.sub.2 O.sub.2 and hypohalous acid concentrations which produce rapid inactivation of heme-containing haloperoxidases.Type: GrantFiled: November 12, 1987Date of Patent: June 26, 1990Assignee: Cetus CorporationInventors: John Geigert, Te-Ning E. Liu, Thabiso N'timkulu
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Patent number: 4707446Abstract: A method of producing a non-heme haloperoxidase which is substantially resistant to inactivation, at room temperature, in up to 0.3M H.sub.2 O.sub.2 for up to 25 hours, and up to 0.5 mM HOCl for up to two minutes. One such haloperoxidase, isolated from Curvularia inaequalis, contains about 2 gram atoms of zinc per molecule. A halogenation reaction employing the enzyme can be performed at H.sub.2 O.sub.2 and hypohalous acid concentrations which produce rapid inactivation of heme-containing haloperoxidases.Type: GrantFiled: May 24, 1983Date of Patent: November 17, 1987Assignee: Cetus CorporationInventors: John Geigert, Te-Ning E. Liu, Thabiso N'timkulu
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Patent number: 4587217Abstract: A method is provided for the production of vicinal heterogeneous dihalogenated products from alkenes and alkynes. The alkene or alkyne is reacted in an aqueous solution of salts of two different halides, an oxidizing agent and an halogenating enzyme. Products provided by the method include novel 2,3-heterogeneously dihalogenated-1,4-butanediols.Type: GrantFiled: May 7, 1984Date of Patent: May 6, 1986Assignee: Cetus CorporationInventors: John Geigert, Saul L. Neidleman
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Patent number: 4546080Abstract: A method is described for the manufacture of commercially useful alpha-halo and alpha-dihalo ketones and aldehydes from alkynes by enzymatic reaction. The alkyne is acted upon in a reaction mixture comprising a halogenating enzyme, an oxidizing agent, and a halide ion source.Type: GrantFiled: January 29, 1981Date of Patent: October 8, 1985Assignee: Cetus CorporationInventors: Saul L. Neidleman, John Geigert
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Patent number: 4503153Abstract: A method is described for the manufacture of aldehydes from primary alcohols by enzymatic reaction. The aldehydes are produced by contacting a primary alcohol with a reaction mixture consisting of chloroperoxidase and hydrogen peroxide.Type: GrantFiled: January 16, 1984Date of Patent: March 5, 1985Assignee: Cetus CorporationInventors: John Geigert, Saul L. Neidleman
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Patent number: 4426449Abstract: A method is described for the manufacture of vicinal dihalogenated products from alkenes and alkynes by enzymatic reaction. The respective alkene or alkyne is contacted with a reaction mixture consisting of halogenating enzyme, an oxidizing agent and a halide ion source.Type: GrantFiled: December 14, 1981Date of Patent: January 17, 1984Assignee: Cetus CorporationInventors: John Geigert, Saul L. Neidleman
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Patent number: 4423149Abstract: A process is described for the production of D-glucosone from glucose. An aqueous solution of glucose is converted substantially completely to D-glucosone by an enzymatic oxidation while removing or utilizing co-produced hydrogen peroxide. D-glucosone is a useful intermediate product which may then be converted to a desired end product.Type: GrantFiled: October 15, 1981Date of Patent: December 27, 1983Assignee: Cetus CorporationInventors: William F. Amon, Jr., John Geigert, Saul L. Neidleman
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Patent number: 4404283Abstract: A method is described for the manufacture of wax esters from saturated hydrocarbons by the metabolic action of microorganisms. These wax esters contain either 0, 1 or 2 internally located carbon-carbon double bonds, with no more than 1 carbon-carbon double bond being in the fatty acid or the fatty alcohol segments. These wax esters are chemically similar to the wax esters of sperm whale oil and jojoba oil, and are useful as lubricants and lubricant additives, for example. They also are a ready source of industrially important mono-ene fatty acids and fatty alcohols, when saponified.Type: GrantFiled: October 10, 1980Date of Patent: September 13, 1983Assignee: Standard Oil Company (Ind.)Inventors: Saul L. Neidleman, John Geigert
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Patent number: 4351902Abstract: A process is described which is useful as a co-process in combination with a process which employs hydrogen peroxide. The process of the invention provides a source of hydrogen peroxide along with a useful co-product, that co-product being 2-keto-D-gluconic acid or products derived therefrom. One of the first and second carbons of D-glucose is oxidized enzymatically to produce hydrogen peroxide and an intermediate product. The other of the first and second carbons of the intermediate product is then oxidized enzymatically to produce hydrogen peroxide and 2-keto-D-gluconic acid. In one form of the invention, the intermediate product is D-glucosone; the final product is 2-keto-D-gluconic acid. In the other form of the invention, the intermediate product is D-glucono-.delta.-lactone; the final product is a mixture of 2-keto-D-gluconic acid and D-isoascorbic acid.Type: GrantFiled: June 16, 1980Date of Patent: September 28, 1982Assignee: Cetus CorporationInventors: Saul L. Neidleman, William F. Amon, Jr., John Geigert
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Patent number: 4284723Abstract: Epoxides or glycols are produced by passing a gaseous olefin through a reaction mixture containing a halogenating enzyme, an oxidizing agent and a halide ion source whereby the olefin is converted to a halohydrin. The halohydrin is converted to an epoxide which may be converted by hydration to a glycol. Conversion of the halohydrin to an epoxide may be carried out enzymatically.Type: GrantFiled: May 16, 1979Date of Patent: August 18, 1981Assignee: Cetus CorporationInventors: Saul L. Neidleman, William F. Amon, Jr., John Geigert
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Patent number: 4282324Abstract: This invention relates to the production of iodine. More particularly, the invention relates to the enzymatic oxidation of iodide to iodine and the recovery of said formed iodine.Type: GrantFiled: June 25, 1979Date of Patent: August 4, 1981Assignee: Cetus CorporationInventors: Saul L. Neidleman, John Geigert
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Patent number: 4247641Abstract: A method is described for the manufacture of epoxides or glycols from olefins. An olefin is contacted with a reaction mixture of a halogenating enzyme, an oxydizing agent and a halide ion source, for a sufficient period to convert the olefin to a halohydrin. The halohydrin is then converted to an epoxide or glycol.Type: GrantFiled: May 29, 1979Date of Patent: January 27, 1981Assignee: Cetus CorporationInventors: Saul L. Neidleman, William F. Amon, Jr., John Geigert
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Patent number: 4246347Abstract: A process is described for the production of fructose from glucose. An aqueous solution of glucose is converted to D-glucosone by an enzymatic process. D-glucosone is then converted to substantially pure fructose by chemical hydrogenation. Fructose may be recovered in crystalline form.Type: GrantFiled: October 24, 1979Date of Patent: January 20, 1981Assignee: Cetus CorporationInventors: Saul L. Neidleman, William F. Amon, Jr., John Geigert