Patents by Inventor John Gerard Flanagan

John Gerard Flanagan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • siRNA useful to supress expression of EIF-5A1
    Patent number: 8242256
    Abstract: The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of factor 5A1. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines by inhibiting expression of apoptosis factor 5A.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: August 14, 2012
    Assignee: Senesco Technologies, Inc.
    Inventors: John E. Thompson, Bruce C. Galton, Catherine Taylor, Adrienne Boone, Elizabeth Heikkila, Dominic Cliche, Shelley Culp-Stewart, John Gerard Flanagan, Michelle Senchyna
  • SiRNA Useful to Suppress expression of eIF-5A1
    Publication number: 20110098460
    Abstract: The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of factor 5A1. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines by inhibiting expression of apoptosis factor 5A.
    Type: Application
    Filed: December 17, 2009
    Publication date: April 28, 2011
    Applicant: Senesco Technologies, Inc.
    Inventors: John E. Thompson, Bruce C. Galton, Catherine Taylor, Adrienne Boone, Elizabeth Heikkila, Dominic Cliche, Shelley Culp-Stewart, John Gerard Flanagan, Michelle Senchyna
  • Use of antisense oligonucleotides or siRNA to suppress expression of eIF-5A1
    Patent number: 7662796
    Abstract: The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of factor 5A1. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines by inhibiting expression of apoptosis factor 5A.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: February 16, 2010
    Assignee: Senesco Technologies, Inc.
    Inventors: John E. Thompson, Bruce C. Galton, Catherine Taylor, Adrienne Boone, Elizabeth Heikkila, Dominic Cliche, Shelley Culp-Stewart, John Gerard Flanagan, Michelle Senchyna
  • Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye
    Patent number: 7381708
    Abstract: The present invention provides methods for preventing retinal ganglion cell death in the glaucomatous eye and methods for suppressing apoptosis-specific eIF5A1 expression through the use of antisense oligonucleotides targeted to human apoptosis-specific eIF5A1.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: June 3, 2008
    Assignee: Sensco Technologies, Inc.
    Inventors: Catherine Taylor, Dominic Cliché, Elizabeth Margaret Heikkila, Diane Michelle Senchyna, John Gerard Flanagan, John E. Thompson
  • Suppression of eIF5A1 expression to prevent retinal ganglion cell death in the glaucomatous eye
    Publication number: 20030225022
    Abstract: The present invention provides methods for preventing retinal ganglion cell death in the glaucomatous eye and methods for suppressing apoptosis-specific eIF5A1 expression through the use of antisense oligonucleotides targeted to human apoptosis-specific eIfF5A1.
    Type: Application
    Filed: March 10, 2003
    Publication date: December 4, 2003
    Inventors: Catherine Taylor, Dominic Cliche, Elizabeth Margaret Heikkila, Diane Michelle Senchyna, John Gerard Flanagan, John E. Thompson